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A domain-specific usherin/collagen IV interaction may be required
A domain-specific usherin/collagen IV interaction may be required

... 100 amino acids, are shared with at least 45 different families of molecules ranging from cytokine receptors to cell surface binding proteins. Different type III domains may be almost completely dissimilar at the amino acid level and as much as 90% structurally similar (Sharma et al., 1999). Like th ...
Article - Andrej Sali
Article - Andrej Sali

... (C) The model of a canine ribosome is shown in a reverse view within the electron microscopy (EM) density map. The position of the ER membrane is indicated by ...
Utilization of iron/organic ligand complexes by marine
Utilization of iron/organic ligand complexes by marine

... siderophores and porphyrins have very high conditional stability constants for iron binding which are nearly identical to those of the natural ligands in seawater (Rue & Bruland 1995, Witter et al. 2000). The goal of this study was to determine the role that organic ligand structure plays in the acq ...
A conserved N-‐terminal domain of Rif2 regulates telomere length in
A conserved N-‐terminal domain of Rif2 regulates telomere length in

... essential  functions;  first  to  protect  the  ends  from  degradation,  recombination,  and   initiation  of  a  damage  response,  and  second  to  regulate  telomere  elongation  by   telomerase.  Telomerase  adds  telomere  repeats  to   ...
Microsoft Word
Microsoft Word

... from ADP and inorganic phosphate using the energy of the electrochemical proton gradient established by the mitochondrial electron transport chain. Pronounced defects in the ATP synthase can cause various disorders, especially in the highly energy-demanding neuromuscular system (Schon et al., 2001, ...
Internal expression of Yarrowia NDH2
Internal expression of Yarrowia NDH2

... 1×10–5 (Barth and Gaillardin, 1996). In our experiment, 5′FOA resistant colonies appeared with approximately 10 times lower frequency. Southern blot analysis of ten colonies demonstrated that, although the URA3 marker had been lost or damaged by spontaneous mutations in all of these strains, the pla ...
Sugar Signaling and Proteolysis in Higher Plants
Sugar Signaling and Proteolysis in Higher Plants

... transduction (Halford et al. 1999). Such an effect has been shown to occur in developing barley seeds, where higher ATP levels were found in tissues in which storage starch is beginning to form (Rolletschek et al. 2004). Inorganic phosphate was also reported to inhibit the expression of sugar-induci ...
Intraflagellar transport molecules in ciliary and nonciliary cells of the
Intraflagellar transport molecules in ciliary and nonciliary cells of the

... 2003; Follit et al., 2006). These experiments verified the expression of all five IFT proteins in the murine retina (Fig. S1, A and B). The antibodies to four IFT proteins each recognized a single band of expected size in retinal protein extracts, which implied that these antibodies are monospecific ...
12 Insights into the mechanisms underlying CFTR channel activity
12 Insights into the mechanisms underlying CFTR channel activity

... ABC proteins and homology models of the CFTR protein in enhancing our understanding of ion permeation and gating by the CFTR channel. We also discuss the potential value of small‑molecule ligands as new tools for identify‑ ing the molecular defects caused by disease‑causing mutations. ...
Physical and chemical interactions between aphids and plants
Physical and chemical interactions between aphids and plants

... plates in case of damage. This suspicion has been confirmed by CLSM studies in which SEs of Vicia faba were damaged. In response to injury inflicted by a microcapillary tip, thick protein deposits readily appeared on the sieve plates and mass flow stopped immediately (Knoblauch and van Bel, 1998). T ...
PPT - Portland State University
PPT - Portland State University

... below. A metastable, dynamic equilibrium between two conformational states of photoexcited rhodopsin, designated MI and MII, is established within a few milliseconds of photon absorption. MII is the conformation which binds and activates the visual G protein, transducin (Gt), as shown in step 1, bel ...
The tumor suppressor Scrib interacts with the zyxin
The tumor suppressor Scrib interacts with the zyxin

... assay, this means that bait- and prey-proteins should be localized in the nucleus. In contrast to the yeast assays, where we used partial bait-proteins, we wanted to use full length bait-proteins in the mammalian assay. However, since LPP contains a nuclear export signal (NES) (amino acids 117–128) ...
Physical and chemical interactions between
Physical and chemical interactions between

... plates in case of damage. This suspicion has been confirmed by CLSM studies in which SEs of Vicia faba were damaged. In response to injury inflicted by a microcapillary tip, thick protein deposits readily appeared on the sieve plates and mass flow stopped immediately (Knoblauch and van Bel, 1998). T ...
Genetic Dissection of Chloroplast Biogenesis and
Genetic Dissection of Chloroplast Biogenesis and

... that first serve as storage organs but become photosynthetically active, to the hypogaeic seedlings, where the cotyledons only serve as a storage organ and are not photosynthetic. Herein, we only refer to chloroplast biogenesis and development in epigaeic seedlings. That chloroplast development proc ...
AtAMT1 gene expression and NH uptake in roots of glutamine levels
AtAMT1 gene expression and NH uptake in roots of glutamine levels

... pool(s) responsible for initiating this control. A coordinated regulation of all forms of nitrogen transport by feedback from downstream metabolites of inorganic N was proposed by Lee and Rudge (1986). The operation of a carbon/nitrogen sensor in microorganisms, the so-called PII protein, that regul ...
Structure of L‑Serine Dehydratase from Legionella
Structure of L‑Serine Dehydratase from Legionella

... At least four types of Fe−S L-serine dehydratases that differ in their domain content and arrangement have been identified.17 They all contain a catalytic or α domain that harbors the binding site for the Fe−S cluster as well as a β domain whose function has not yet been completely defined. In the type ...
A Calcium-Regulated Gatekeeper in Phloem Sieve Tubes
A Calcium-Regulated Gatekeeper in Phloem Sieve Tubes

... (Nakamura et al., 1993). Volk and Franceschi (2000) showed evidence of a calcium channel in the sieve element plasma membrane of tobacco and of the aquatic plant Pistia stratiotes using immunolabeling with antibodies to a calcium channel protein. These authors proposed that calcium channels become a ...
Structural Basis for Bivalent Smac-Mimetics Recognition in the IAP
Structural Basis for Bivalent Smac-Mimetics Recognition in the IAP

Efficiency and Diversity of Protein Localization by Random Signal Sequences.
Efficiency and Diversity of Protein Localization by Random Signal Sequences.

... sequence of the maltose-binding protein of Escherichia coli, there appear to be two amino acid positions that can be mutated to block maltose-binding protein export and give rise to a pronounced maltose growth defect (6). The absolutely defective mutations almost always introduce charged residues in ...
Characterisation of Plasmodium falciparum proteins expressed on
Characterisation of Plasmodium falciparum proteins expressed on

A Stable Serine Protease, Wrightin, from the Latex of the Plant
A Stable Serine Protease, Wrightin, from the Latex of the Plant

... proper activity and, thus, are not so economical and handy. In contrast, serine proteases from plant sources are both stable and active under harsh conditions (at temperatures of 70–80 °C and high pH), in the presence of surfactants or oxidizing agents; thus, they are more useful and economical for ...
Proteolytic Degradation of Hemoglobin in the Intestine of the Human
Proteolytic Degradation of Hemoglobin in the Intestine of the Human

... specific primers were designed for 5' and 3' rapid amplification of cDNA ends (RACE) using adult N. americanus RNA (GeneRacer; Invitrogen), as described elsewhere [19]. The full-length cDNA sequence of Na-mep-1 was obtained by creating a consensus consisting of the 5' and 3' RACE products and the BG ...
Adaptation of Microorganisms to Cold Temperatures, Weak Acid
Adaptation of Microorganisms to Cold Temperatures, Weak Acid

... ABSTRACT: The application of physical stress to microorganisms is the most widely used method to induce cell inactivation and promote food stability. To survive, microorganisms have evolved both physiological and genetic mechanisms to tolerate some extreme physical conditions. This is clearly of sig ...
A Lipid Transfer–like Protein Is Necessary for Lily
A Lipid Transfer–like Protein Is Necessary for Lily

... large amount of material (10 mg) was loaded, as shown in Figure 5B. When this 9-kD protein was eluted from the SDS gel and combined with the petal homogenate or a citratesoluble stylar extract, each fraction of which had no adhesion activity alone, the mixtures showed adhesion activity (Tables 1 and ...
Trans-chalcone and quercetin down-regulate fatty acid synthase
Trans-chalcone and quercetin down-regulate fatty acid synthase

... described in the scientific literature as FAS inhibitors (quercetin, trans-chalcone, ellagic acid, luteolin, galangin, and genistein) against the dermatophyte Trichophyton rubrum and their effects on fatty acid and ergosterol synthesis. Methods: The antifungal activity of the natural products was te ...
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Magnesium transporter

This page links directly from the magnesium in biological systems page.Magnesium transporters are proteins that transport magnesium across the cell membrane. All forms of life require magnesium, yet the molecular mechanisms of Mg2+ uptake from the environment and the distribution of this vital element within the organism are only slowly being elucidated.In bacteria, Mg2+ is probably mainly supplied by the CorA protein and, where the CorA protein is absent, by the MgtE protein. In yeast the initial uptake is via the Alr1p and Alr2p proteins, but at this stage the only internal Mg2+ distributing protein identified is Mrs2p. Within the protozoa only one Mg2+ transporter (XntAp) has been identified. In metazoa, Mrs2p and MgtE homologues have been identified, along with two novel Mg2+ transport systems TRPM6/TRPM7 and PCLN-1. Finally, in plants, a family of Mrs2p homologues has been identified along with another novel protein, AtMHX.
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