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(NSAIDs) classification, diagnosis and management
(NSAIDs) classification, diagnosis and management

... hypersensitivity may reach 25.6% (9). Cutaneous manifestations to NSAIDs may affect 0.3% of general population (5), and the prevalence of aspirin hypersensitivity may be as high as 27–35% in patients with chronic urticaria (10). NSAIDs have been reported to be the major (11) or the second group of d ...
POWERPOINT SPECIALS
POWERPOINT SPECIALS

Patient Information Sheet YOUR PRESCRIPTION FOR BALACET
Patient Information Sheet YOUR PRESCRIPTION FOR BALACET

... Symptoms of Propoxyphene Overdosage The manifestations of acute overdosage with propoxyphene are those of narcotic overdosage. The patient is usually somnolent but may be stuporous or comatose and convulsing. Respiratory depression is characteristic. The ventilatory rate and/or tidal volume is decre ...
Sample
Sample

... 10. In response to criticism related to the time lag for drug approval, which act was passed in 1997? a. Compassionate Use IND Incorrect Feedback: The Compassionate Use IND is an application that is filed with the FDA to prescribe a drug for a life-threatening disease; it does not deal with the time ...
What single drug is the most efficacious for oral conscious minimal
What single drug is the most efficacious for oral conscious minimal

... One way of managing patients with mild to moderate levels of dental anxiety is through the use of oral conscious sedation. Unfortunately most systematic reviews on this subject have focused on children rather than adults. The objective of this literature review was therefore to evaluate the existing ...
sound asleep: medications and behavioral strategies for older adults
sound asleep: medications and behavioral strategies for older adults

... ___________________________________ ___________________________________ ___________________________________ ___________________________________ ___________________________________ ___________________________________ ___________________________________ ...
Hypersensitivity to nonsteroidal antiinflammatory drugs (NSAIDs
Hypersensitivity to nonsteroidal antiinflammatory drugs (NSAIDs

... hypersensitivity may reach 25.6% (9). Cutaneous manifestations to NSAIDs may affect 0.3% of general population (5), and the prevalence of aspirin hypersensitivity may be as high as 27–35% in patients with chronic urticaria (10). NSAIDs have been reported to be the major (11) or the second group of d ...
Clinical Implications of Dihydropyrimidine
Clinical Implications of Dihydropyrimidine

... The importance of DPD to the clinical pharmacology of 5-FU has been further established by several recent observations (Table 1) that demonstrate that DPD can account for much of the variability that has been noted in clinical studies with 5-FU. This includes both intrapatient differences (circadian ...
Expert Opin. Ther. Pat. 2016, 27, 179–189
Expert Opin. Ther. Pat. 2016, 27, 179–189

... poly(alkylene oxides) in order to increase its circulating halflife and thus, treat or prevent staphylococcal infection at less frequent dosages than the unmodified compound. The inventors study thoroughly the effects of this PEGylation on decreased antibody binding and increased bacterial killing, ...
- International Journal of Advanced Biological and
- International Journal of Advanced Biological and

... world. Its roots possess some nutritive value and medicinal properties. They are widely used as a cold beverage, in preparing some pharmaceutical preparations such as haematinic pills and to disguise the bitter taste of other remedies (Fenwick et al., 1990). Glycyrrhiza glabra Linn is one of the mos ...
Multidrug resistance in epilepsy: rats with drug
Multidrug resistance in epilepsy: rats with drug

... of pharmacoresistant epilepsy, but rather points to nonspecific and possibly adaptive mechanisms, such as decreased drug uptake into the brain by intrinsic or acquired overexpression of multidrug transporters in the blood–brain barrier (BBB) (Sisodiya, 2003). There is now a body of evidence that mul ...
Telfast 180mg
Telfast 180mg

... Interaction with other medicinal products and other forms of interaction Fexofenadine does not undergo hepatic biotransformation and therefore will not interact with other drugs through hepatic mechanisms. Coadministration of fexofenadine hydrochloride with erythromycin or ketoconazole has been foun ...
Anti-Nicotine Vaccine: An Insight
Anti-Nicotine Vaccine: An Insight

... The history of anti-addiction vaccines dates back to 1972 when Berkovitz et al. at the University of Chicago immunized a rhesus monkey against morphine. The animal showed protection against heroin and thus they concluded “That this blockade has been shown to be dose-dependent, and it could be overco ...
Interactions between the cytochrome P450 system and
Interactions between the cytochrome P450 system and

... the phase I reactions. They are mediated by the family of enzymes that constitute the CYP system. At least 17 mammalian CYP gene families have been defined, and more than 30 human gene products have been identified.11,12 CYPs with 40% or greater DNA sequence homology are classified in the same famil ...
4. concern in the use of naltrexone
4. concern in the use of naltrexone

... They are probably best observed in an emergency department unless the condition is mild. See fax sheet 6: Heroin withdrawal precipitated by naltrexone. Naltrexone and liver disease Naltrexone in higher doses than usually prescribed can cause a reversible rise in transaminases. Check LFTs before star ...
Review Article Amla (Emblica officinalis) – Medicinal Food and
Review Article Amla (Emblica officinalis) – Medicinal Food and

... suggest that it has anti-viral properties and also functions as an anti-bacterial and anti-fungal agent. The gelatinous plum-sized Amla fruit contains naturally occurring vitamin, heat stable vitamin C. A clinical study on patients with pulmonary tuberculosis showed that the vitamin C contained in E ...
Actonel 75mg and 150mg.pub
Actonel 75mg and 150mg.pub

... improve patient compliance, but has not provided any published data to support this contention. The submitted evidence demonstrates similar efficacy and side-effect profile as risedronate sodium 5mg taken once daily. Improvements in gastrointestinal tolerance and compliance have not been proven. In ...
Parkinson`s and Tremor - Parkinson`s New Zealand
Parkinson`s and Tremor - Parkinson`s New Zealand

... released by the nerve cells to send messages to other nerve cells. This degeneration of the dopamine system produces a loss of inhibition of certain brain structures. This causes parts of the nervous system to fire rhythmically causing a tremor. ...
Migraine — Current Understanding and Treatment
Migraine — Current Understanding and Treatment

... loss, fetal abnormalities, hematologic and liver abnormalities 5–15 mg daily Tiredness, weight gain, depression, ...
Salvinorin A, an Active Component of the Hallucinogenic Sage
Salvinorin A, an Active Component of the Hallucinogenic Sage

... cRNA synthesis, and the mMESSAGE MACHINE kit (Ambion, Austin, TX) was used to generate capped cRNA. Cell Lines and Maintenance. A stable line expressing the human KOR (hKOR-293) was obtained by transfecting an hKOR expression vector (hKOR-pIRESNEO) into human embryonic kidney293 cells (maintained an ...
PrSOLU-MEDROL
PrSOLU-MEDROL

... situation of stress occurring during that period, hormone therapy should be reinstituted. Since methylprednisolone, like prednisolone, suppresses endogenous adrenocortical activity, it is highly important that the patient receiving SOLU-MEDROL be under careful observation, not only during the course ...
Suggestion from clinicians
Suggestion from clinicians

... LDL-cholesterol. There was no dose-related effect of rosuvastatin on blood HDL-cholesterol, but overall, rosuvastatin increased HDL by 7%. There is a high risk of bias for the trials in this review, which would affect WDAEs, but unlikely to affect the lipid measurements. WDAEs were not statistically ...
Therapeutic and systemic side effects of ocular beta
Therapeutic and systemic side effects of ocular beta

... isoproterenol blocking activity at this dose (Table 2). However, higher doses (>316 Mg/kg) produce a complete antagonism of isoproterenol induced cardiac responses with little effect on blood pressure responses.5 Discussion The systemic absorption and resultant side effects of ocularly applied agent ...
Effects of Acute and Repeated Administration of Oxycodone and
Effects of Acute and Repeated Administration of Oxycodone and

... Department of Pharmacology and Toxicology, School of Medicine, Virginia Commonwealth University, Richmond, Virginia Received August 24, 2015; accepted October 20, 2015 ...
end of life medicines information pack
end of life medicines information pack

... for breathlessness or anxiety/agitation whilst waiting for professional support ...
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Psychopharmacology



Psychopharmacology (from Greek ψῡχή, psȳkhē, ""breath, life, soul""; φάρμακον, pharmakon, ""drug""; and -λογία, -logia) is the scientific study of the effects drugs have on mood, sensation, thinking, and behavior. It is distinguished from neuropsychopharmacology, which emphasizes the correlation between drug-induced changes in the functioning of cells in the nervous system and changes in consciousness and behavior.The field of psychopharmacology studies a wide range of substances with various types of psychoactive properties, focusing primarily on the chemical interactions with the brain.Psychoactive drugs interact with particular target sites or receptors found in the nervous system to induce widespread changes in physiological or psychological functions. The specific interaction between drugs and their receptors is referred to as ""drug action"", and the widespread changes in physiological or psychological function is referred to as ""drug effect"". These drugs may originate from natural sources such as plants and animals, or from artificial sources such as chemical synthesis in the laboratory.
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