In vitro and in vivo evaluation of a new sublingual tablet system for
... Oromucosal delivery of drugs promotes rapid absorption and high bioavailability, with subsequent almost immediate onset of pharmacological effect. However, many oromucosal delivery systems are compromised by the possibility of the patient swallowing the active substance before it has been released a ...
... Oromucosal delivery of drugs promotes rapid absorption and high bioavailability, with subsequent almost immediate onset of pharmacological effect. However, many oromucosal delivery systems are compromised by the possibility of the patient swallowing the active substance before it has been released a ...
Safe Handling of Hazardous Drugs
... Health (NIOSH) on the basis of at least one of the following six criteria: carcinogenicity, teratogenicity or developmental toxicity, reproductive toxicity in humans, organ toxicity at low doses in humans or animals, genotoxicity, and new drugs that mimic existing hazardous drugs in structure or tox ...
... Health (NIOSH) on the basis of at least one of the following six criteria: carcinogenicity, teratogenicity or developmental toxicity, reproductive toxicity in humans, organ toxicity at low doses in humans or animals, genotoxicity, and new drugs that mimic existing hazardous drugs in structure or tox ...
Thomas Geller, Laura Loftis and David S. Brink 2004;113;e365 Pediatrics
... presence of major metabolites of drugs of abuse including 11-nor-␦-9-THC-9-carboxylic acid (11-carboxy-THC), a marijuana metabolite. Although the urinary elimination half-life of 11-nor-␦-9-THC-9carboxylic acid averages 3.0 days, with a range of 0.8 to 9.8 days in heavy smokers of marijuana,7 the ur ...
... presence of major metabolites of drugs of abuse including 11-nor-␦-9-THC-9-carboxylic acid (11-carboxy-THC), a marijuana metabolite. Although the urinary elimination half-life of 11-nor-␦-9-THC-9carboxylic acid averages 3.0 days, with a range of 0.8 to 9.8 days in heavy smokers of marijuana,7 the ur ...
PRACTICAL THERAPEUTICS Drugs 45 (6): 918
... or discomfort centred in the upper abdomen) in the general population approaches 25%. By definition, patients with functional dyspepsia do not have a structural'or biochemical explanation for their symptoms. Disorders of function (e.g. delayed gastric emptying) are detectable in a proportion of pati ...
... or discomfort centred in the upper abdomen) in the general population approaches 25%. By definition, patients with functional dyspepsia do not have a structural'or biochemical explanation for their symptoms. Disorders of function (e.g. delayed gastric emptying) are detectable in a proportion of pati ...
Phebra Benztropine 2 mg in 2 mL Injection
... Mental confusion and excitement may occur with large doses, or in susceptible patients. Visual hallucinations have been reported occasionally. Furthermore, in the treatment of extrapyramidal symptoms due to central nervous system drugs, such as phenothiazines and reserpine, in patients with mental d ...
... Mental confusion and excitement may occur with large doses, or in susceptible patients. Visual hallucinations have been reported occasionally. Furthermore, in the treatment of extrapyramidal symptoms due to central nervous system drugs, such as phenothiazines and reserpine, in patients with mental d ...
CURRICULUM VITAE Stacey C. Sigmon, Ph.D. February 2014
... Higgins, S.T., Sigmon, S.C., & Heil, S.H. (2011). Contingency management in the treatment of substance use disorders: Trends in the literature. In P. Ruiz & E. Strain (Eds.), Lowinson & Ruiz’s Substance Abuse: A Comprehensive Textbook, Fifth Edition. Maryland: Lippincott Williams & Wilkins, pp. 603- ...
... Higgins, S.T., Sigmon, S.C., & Heil, S.H. (2011). Contingency management in the treatment of substance use disorders: Trends in the literature. In P. Ruiz & E. Strain (Eds.), Lowinson & Ruiz’s Substance Abuse: A Comprehensive Textbook, Fifth Edition. Maryland: Lippincott Williams & Wilkins, pp. 603- ...
Teratogenicity as a Consequence of Drug-Induced
... Sköld, A.-C. 2000. Teratogenicity as a consequence of drug-induced embryonic cardiac arrhythmia. Common mechanism for almokalant, sotalol, cisapride, and phenytoin via inhibition of IKr. Acta Universitatis Upsaliensis. Comprehensive Summaries of Uppsala Dissertations from the Faculty of Pharmacy 235 ...
... Sköld, A.-C. 2000. Teratogenicity as a consequence of drug-induced embryonic cardiac arrhythmia. Common mechanism for almokalant, sotalol, cisapride, and phenytoin via inhibition of IKr. Acta Universitatis Upsaliensis. Comprehensive Summaries of Uppsala Dissertations from the Faculty of Pharmacy 235 ...
Natural Flavonoids Isolated From the Leaves of Enhydra
... In this study, the flavonoid isolated from the leaves of Enhydra fluctuans shows anti inflammatory activity by inhibiting COX-2 and 5-LOX. LOX. Moreover, flavonoid isolated from the leaves of Enhydra fluctuans exhibits in in-vitro on key enzymes of arachidonic acid cascade involved in the mediation ...
... In this study, the flavonoid isolated from the leaves of Enhydra fluctuans shows anti inflammatory activity by inhibiting COX-2 and 5-LOX. LOX. Moreover, flavonoid isolated from the leaves of Enhydra fluctuans exhibits in in-vitro on key enzymes of arachidonic acid cascade involved in the mediation ...
sanofi-aventis Canada Inc. Date of Revision: 2150 St. Elzear Blvd. West
... Blood and lymphatic system disorders: Thrombocytopenia, purpura, leukopenia, hemolytic anaemia (may be related to hypersensitivity reactions) and decreased hemoglobin have been observed. Thrombocytopenia with or without purpura has occurred when RIFADIN and ethambutol were administered concomitantly ...
... Blood and lymphatic system disorders: Thrombocytopenia, purpura, leukopenia, hemolytic anaemia (may be related to hypersensitivity reactions) and decreased hemoglobin have been observed. Thrombocytopenia with or without purpura has occurred when RIFADIN and ethambutol were administered concomitantly ...
Review on clinical studies with cannabis and cannabinoids 2010-2014
... tetrahydrocannabinol, THC, CBD, dronabinol, Marinol, nabilone, Cannador, nabiximols and Sativex. For the final selection, only properly controlled clinical trials were retained. Open-label studies were excluded, except if they were a direct continuation of a study discussed here. Thirty-two controll ...
... tetrahydrocannabinol, THC, CBD, dronabinol, Marinol, nabilone, Cannador, nabiximols and Sativex. For the final selection, only properly controlled clinical trials were retained. Open-label studies were excluded, except if they were a direct continuation of a study discussed here. Thirty-two controll ...
hydrogels: a review - Global Research Online
... Drug or drug polymer conjugates are mixed with polymer precursor solution and hydrogel network formation and drug encapsulation are achieved simultaneously. Here release of drugs occurs through diffusion, hydrogel swelling, reversible drug-polymer interaction, degradation of labile covalent bonds. D ...
... Drug or drug polymer conjugates are mixed with polymer precursor solution and hydrogel network formation and drug encapsulation are achieved simultaneously. Here release of drugs occurs through diffusion, hydrogel swelling, reversible drug-polymer interaction, degradation of labile covalent bonds. D ...
MODERN TASTE CONCEALING TECHNIQUES IN
... and the core material in the manufacturing vehicle. Deposition of the liquid polymer coating around the core material occurs if the polymer is absorbed at the interface formed between the core material and the liquid vehicle phase, and this adsorption phenomenon is a prerequisite to the effective co ...
... and the core material in the manufacturing vehicle. Deposition of the liquid polymer coating around the core material occurs if the polymer is absorbed at the interface formed between the core material and the liquid vehicle phase, and this adsorption phenomenon is a prerequisite to the effective co ...
Solid Lipid Nanoparticles as Efficient Drug and Gene Delivery
... Solid lipid nanoparticles (SLNs) as example of lipid based drug delivery system have distinctive property such as high drug loading, large surface area and can protect the drug from the environment, while increasing its bioavailability. Consequently, two noticeable advantages can be attained; first, ...
... Solid lipid nanoparticles (SLNs) as example of lipid based drug delivery system have distinctive property such as high drug loading, large surface area and can protect the drug from the environment, while increasing its bioavailability. Consequently, two noticeable advantages can be attained; first, ...
Prescriptions Pain Medications FAQs
... source of harm or abuse. We all must ensure that accurate information about both the legitimate use and the abuse of prescription pain medications is made available. The roles of both health professionals and law enforcement personnel in maintaining this essential balance between patient care and di ...
... source of harm or abuse. We all must ensure that accurate information about both the legitimate use and the abuse of prescription pain medications is made available. The roles of both health professionals and law enforcement personnel in maintaining this essential balance between patient care and di ...
FAQ in Word format - Help for Headaches
... professionals in the law enforcement and regulatory communities about the medical treatment of pain. The goal is to achieve a better balance in addressing the treatment of pain while preventing abuse and diversion of pain medications. The authors of this document stand committed to the core principl ...
... professionals in the law enforcement and regulatory communities about the medical treatment of pain. The goal is to achieve a better balance in addressing the treatment of pain while preventing abuse and diversion of pain medications. The authors of this document stand committed to the core principl ...
Guideline on the investigation of drug interactions - EMA
... of hospital admissions as a result of medically important, sometimes serious or even fatal adverse events. Drug-drug interactions can also cause partial or complete abolishment of treatment efficacy. The ageing European population, where polypharmacy is more frequent, increases the likelihood of suc ...
... of hospital admissions as a result of medically important, sometimes serious or even fatal adverse events. Drug-drug interactions can also cause partial or complete abolishment of treatment efficacy. The ageing European population, where polypharmacy is more frequent, increases the likelihood of suc ...
draft report - Canadian Ophthalmological Society
... medicinal product is frequently associated with a dearth of clinical evidence regarding the effects of the product in populations that are not covered by the regulatory approval, this is not the case for bevacizumab, for which there is a relatively substantive evidence base available across several ...
... medicinal product is frequently associated with a dearth of clinical evidence regarding the effects of the product in populations that are not covered by the regulatory approval, this is not the case for bevacizumab, for which there is a relatively substantive evidence base available across several ...
Traditional Indian spices and their health significance
... to provide science-based evidence for the traditional uses and to develop either functional foods or nutraceuticals. The Indian traditional medical systems use turmeric for wound healing, rheumatic disorders, gastrointestinal symptoms, deworming, rhinitis and as a cosmetic. Studies in India have exp ...
... to provide science-based evidence for the traditional uses and to develop either functional foods or nutraceuticals. The Indian traditional medical systems use turmeric for wound healing, rheumatic disorders, gastrointestinal symptoms, deworming, rhinitis and as a cosmetic. Studies in India have exp ...
Drugs and Thyroid - Journal of the Association of Physicians of India
... esting of thyroid function is becoming common in clinical practice. Many patients tested, are on multiple medications for various medical conditions. This is particularly true of elderly patients. It is widely recognized that certain drugs can alter thyroid hormone measurements and can cause confusi ...
... esting of thyroid function is becoming common in clinical practice. Many patients tested, are on multiple medications for various medical conditions. This is particularly true of elderly patients. It is widely recognized that certain drugs can alter thyroid hormone measurements and can cause confusi ...
Sorting Through the Science on Marijuana: Facts, Fallacies,
... anandamide. The consequence of this receptor stimulation is the experience of mild euphoria, altered perception of time, relaxation, difficulty with memory and concentration, and intensification of sensory experiences. Regular users of marijuana typically find these effects pleasurable or reinforcin ...
... anandamide. The consequence of this receptor stimulation is the experience of mild euphoria, altered perception of time, relaxation, difficulty with memory and concentration, and intensification of sensory experiences. Regular users of marijuana typically find these effects pleasurable or reinforcin ...
Chapter 18 - The RedZone
... Mosby items and derived items © 2011, 2007, 2004 by Mosby, Inc., an affiliate of Elsevier Inc. ...
... Mosby items and derived items © 2011, 2007, 2004 by Mosby, Inc., an affiliate of Elsevier Inc. ...
William Llewellyn`s ANABOLICS
... The photographic database has been extensively expanded, and includes approximately 3,000 pictures of anabolic/androgenic steroids and other drugs. Legitimate pharmaceuticals are labeled and grouped by their country of manufacture. The following terms are used to identify the origin of individual dr ...
... The photographic database has been extensively expanded, and includes approximately 3,000 pictures of anabolic/androgenic steroids and other drugs. Legitimate pharmaceuticals are labeled and grouped by their country of manufacture. The following terms are used to identify the origin of individual dr ...
Psychopharmacology
Psychopharmacology (from Greek ψῡχή, psȳkhē, ""breath, life, soul""; φάρμακον, pharmakon, ""drug""; and -λογία, -logia) is the scientific study of the effects drugs have on mood, sensation, thinking, and behavior. It is distinguished from neuropsychopharmacology, which emphasizes the correlation between drug-induced changes in the functioning of cells in the nervous system and changes in consciousness and behavior.The field of psychopharmacology studies a wide range of substances with various types of psychoactive properties, focusing primarily on the chemical interactions with the brain.Psychoactive drugs interact with particular target sites or receptors found in the nervous system to induce widespread changes in physiological or psychological functions. The specific interaction between drugs and their receptors is referred to as ""drug action"", and the widespread changes in physiological or psychological function is referred to as ""drug effect"". These drugs may originate from natural sources such as plants and animals, or from artificial sources such as chemical synthesis in the laboratory.