Download LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034

LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034
M.Sc. DEGREE EXAMINATION – BIOMEDICAL INSTRUMENTATION
THIRD SEMESTER – NOV 2006
AG 11
BI 3951 - IMMUNOTECHNOLOGY
Date & Time : 30-10-2006/9.00-12.00
Dept. No.
Max. : 100 Marks
PART A
Answer all the questions
10X2=20
1. List out the steps involved in transplant rejection.
2. What is meant by Fruend’s Adjuvant?
3. Define Haptens.
4. Comment on the properties of c1 serum Protein.
5. State the principle of nephelometry.
6. Define subunit vaccines. Give examples.
7. List out the different tests adopted for tissue typing.
8. Comment on the characteristic features of Ig M.
9. What is meant by ADCC?
10. List out the applications of monoclonal antibodies.
PART B
Answer any four of the following
4X10=40
11. Explain the different types of antibody classes.
12. Describe cytosolic pathway involved in antigen presentation.
13. Define allograft. Describe the different types of transplantation rejection.
14. Bring out the role of tumour antigens in tumour immunology.
15. Explain the characteristic features of B-cell and T-cell Epitopes.
16. Explain the differentiation of immune cells from haematopoetic stem cells.
PART-C
Answer any two of the following
2X20=40
17. What are Anaphylatoxins? Explain in detail the different types of
hypersensitive reactions.
18. Explain in detail any two autoimmune disorders.
19. Describe the different immunochemical methods adopted in antigen and
antibody estimation.
20. Write in detail B-cell mediated immunodeficiency disorders.
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