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Transcript
THE IMMUNE SYSTEM Bone marrow Stem cells B-cells Challenge & Response Infection = Challenge Reaction of immune system = Response Self & Non-self Molecules which belong to the body = Self Antigens which are foreign = Non-self T-Cells Antigen presented independently Thymus gland B-cell primed Helper TH-cells Stimulate specific B-cell to develop Macrophages Phagocytose pathogens and present antigen to Tcell along with Class II MHC protein. Suppressor TS-cells Cytotoxic TE-cells Switch off immune response Lyse cancer cells and cells infected by viruses Plasma cell clone Memory cells Specific antibody produced • • • Agglutination of toxins and pathogens. Attraction of macrophages. Activation of complement enzymes in the plasma. Phagocytosis Humeral response Cell-mediated response For pathogens in the blood stream, lungs, skin and gut. For pathogens inside cells (eg viruses) and cancerous cells. The lymphocyte must recognise both SELF (MHC) proteins and NONSELF antigen. © Paul Billiet 2007 The Open Door Web Site
