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PSYC327 Neuropsychology Dr. Carolyn Wilshire EA314, ext. 6036 Email [email protected] Course website: http://pavlov.psyc.vuw.ac.nz/327 Don’t Forget: • Fill in lab preference sheet, and hand to me or Psyc 327 box (outside EA402) by Wed 5pm Class lists avail. Thurs 2pm on Third year notice board and website. • Textbooks have arrived at Book Centre! • Lab manual: Available tomorrow morning Today’s Lecture 1. What is Neuropsychology? - Scientific discipline vs. clinical profession - Relation to biological psychology 2. The Neuron - Basic structure - Transmission within and between neurons • Weds and Thurs: gross anatomy of the brain What is Neuropsychology? Ref: Banich Ch. 1 pp. 4-6 1. A scientific discipline 2. A clinical profession 1. A scientific discipline: • What functions are supported by frontal lobes? • Do the left and right hemispheres support different abilities? • How does temporal lobe damage affect human function? -> relating anatomy to function 1. A scientific discipline: • Which parts of the brain are involved in visual processing? • Memory impairments - which memories are most/least affected? • What types of language problems can occur? What can these tell us about language? -> relating function to anatomy Relationship to Other Fields Biological Psyc /Brain and Behaviour: – All aspects of behaviour(sex, hunger, learning, attention, motivation, sensation, etc.) – Animal and human models Neuropsychology: – Emphasis on higher level functions high-level perception, memory, language – Largely human models : brain damage & imaging e.g. 2. A Clinical Profession: • Patient with problems recognizing objects - which region is damaged? • Scans show damage to left frontal lobe - which abilities should be assessed? • P can't recognize faces- what can his/her family expect? • P has difficulties finding words - use cognitive models of word retrieval to plan therapy The Neuron Ref: Banich Ch. 1 pp. 41-46 Demonstration: 1.1.1 Transmission within Neurons Transmission is Electrical: • When sufficiently stimulated, cell "fires“ • Positive charge transmitted down axon Demonstration: 1.1.1, 1.2.4 The Synapse Transmission between Neurons Transmission is Chemical: • Charge releases neurotransmitters (NT's) Demonstration: 1.4.1, 1.4.2 • NT's bind to receptors Neurotransmitters • Types: acetylcholine serotonin noradrenalin (norepinephrine) dopamine • Receptors are specific for certain NT's e.g. dopamine binds to dopamine receptors • NT's can have excitatory or inhibitory effects - > increase or decrease likelihood of firing Neuron Parts are Colour-coded: • Axons are white • Cell bodies are grey • Grey Matter = areas with many cell bodies e.g. cerebral cortex (outside layer of the brain) • White matter = areas with many axons e.g. connecting fibres between areas of cortex Neuron Parts are colour coded: