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Transcript
RNA Structure and Function,
Transcription and Translation
RNA (RIBONUCLEIC ACID)
Function:
• All traits you have due to proteins of amino acids
• Genes contain “blueprints” to make protein
• Ribosomes are site of protein synthesis
• RNA reads blueprints & makes protein
Structure:
• Single Strand
• Sugar = ribose
• Phosphate group
• Bases = adenine, guanine, cytosine, URACIL (replaces T)
Types:
• mRNA: messenger (carries info to ribosome)
• tRNA: transfer (moves amino acids to ribosome)
• rRNA: ribosomal (makes up ribosomes)
Gene Expression:
• Transcription: RNA copy of gene made from DNA molecule
• Translation: Proteins made
DNA
RNA
Transcription
PROTEIN
Translation
PRACTICE
DNA = ATCGATACG
Complementary DNA =
mRNA =
TAGCTATGC
AUCGAUACG
DNA = TCCGTACGA
Complementary DNA =
AGGCATGCT
mRNA =
UCCGUACGA
PROTEIN SYNTHESIS
(TRANSLATION)
The Genetic Code
• Every 3 nucleotides in mRNA code for specific amino acid; triplet or
codon
• Genetic code is universal; same in all organisms
• tRNA anticodon is complementary to mRNA codon; picks up amino
acids
THE GENETIC CODE
mRNA CODONS
Exon – gene that is expressed;
coding portion of dna
Intron – gene that is not expressed;
non-coding portion of dna
PRACTICE
What amino acids are coded for by the following mRNA codons?
GUC
Val
CCG
Pro
UAC
Tyr
UCG
Ser
AAA
Lys
GCA
Ala
What are the possible codons for the following series of amino
Phe – Tyr - Met
UUU UAU AUG
UUC UAC
acids?
What are the complementary mRNA codons to the tRNA
UUU
AAA
UGC
ACG
AGA
UCU
anticodons?