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AP Biology
Chapter 15 Guided Reading Assignment
Name _________________________
1. What is the chromosomal basis of inheritance?
2. What does wild type mean?
3. Explain the chromosomal basis of sex determination in the following organism:
a. Mammals
b. Grasshoppers
c. Birds and some fish
d. Bees and ants
4. What is the SRY gene and why is it important?
5. What is a sex-linked gene?
6. What is X inactivation?
7. Why are most Calico cats female?
8. What are linked genes?
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9. In Morgan’s second experiment involving the seemingly linked traits of body color and
wing size, he noticed that some unexpected, non-parental-type offspring were
produced. What did he attribute this result to? Explain.
10. In what step of meiosis, would recombinants form and why?
11. Compare and contrast a genetic map, a linkage map, and a cytogenetic map.
12. On this linkage map, which two genes would be most likely to cross over?
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13. What is nondisjunction and when in meiosis can it occur?
14. Define the following terms:
a. Aneuploidy
b. Monosomic
c. Trisomic
d. Polyploidy
15. Label the following alterations in chromosomal structure. Define the term alongside
the diagram. These terms will be used in the coming chapters.
16. What is a nonreciprocal crossover and what can it result in?
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17. Explain the following human disorders that result from chromosomal alterations.
a. Down Syndrome
b. Klinefelter Syndrome
c. Turner Syndrome
18. What is genomic imprinting?
19. What are extranuclear genes? Why are they only passed down maternally?
20. What are two human diseases carried in maternal mitochondria?
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