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GENETICS VIA SESAME STREET CHARACTERS adapted by W. Marble Essential Question: Why do we “look like we do”? Engage: Using the “Mendelian Inheritance In Humans” handout, students will take a look at the traits they have and don’t have. Terminology is gone over as the terms and questions about the terms come up while the students look/ go through the recording sheet and the handout. Once they go through what each trait looks like, determine if it is dominant or recessive, and record their own phenotype, class needs to combine their info to come up with some sort of “explanation”. Students commit to what they think about the data and what it means to them writing in their lab notebook. Discussion then continues at home and comes back into the classroom the next day. Explore: A 15 minute video “How Do Your Genes Fit” goes into some info about just how a person ends up with, in this case, a genetic disorder. Punnett Squares are introduced along with “Gregor Mendel”. To practice using Punnett squares, students will draw one bean from each of two bags prepared (50 white in one and 25 white and 25 red in the other) to determine the “sex” of their offspring. “Probability” is discussed (and discussed...!) and is related to their math class work, gaming, lottery... Explain: Reference back to the unit just finished over Reproductive Systems/Sexual reproduction. Students are reminded that each child received one set of info from their mother via the egg and one set of info from their father via the sperm and they all started as a single cell that rapidly multiplied. Using Sesame Street Character Dolls, the question is “What if Zoe and Elmo fell in love, got married, and had a child? What would their offspring look like?” As a group, students discuss possibilities and come up with which traits they think should be dominant and which should be recessive traits for each character including a list of codes for each trait. Since there are several body colors, co-dominance traits are created and “new colors” form. Terms are reviewed from the Mendelian work done prior and new terms are added. The practice making Punnet Squares in class to see the possible “outcomes” for their new Sesame Street baby. Elaborate: Students will choose their “Parents” and create Punnett Squares from these two to create possible offspring. They are then to choose a mate for their child and create a new offspring.... this will continue until they have four generations. They MUST NOT mate with a relative (I encourage students to get their codes from other classes other than just theirs). Their end product is some sort of “Photo Album” that they create which MUST have pictures of their “family” and the Punnett Squares with the chosen codes circled. I share examples from the year before in case anyone needs inspiration! Extend: Lastly, they have to choose a genetic disorder that they will research and present their findings to the class. I encourage them to choose something that they have in their family or that they just found very interesting from their general search and want to find out more. The final product is strictly their choice but the criteria are mine. Students are given time in class to do the research using their computers and the library (which seems like they use this resource less and less) Again, I show examples from the past years which range from videos to reports, slide shows to posters. All students must present in front of the class. (And of course I still allow those few who just “can’t” GENETICS via SESAME STREET CHARACTERS present in front of the class present to me during recess...this is only a last resort after MUCH coaxing!) Evaluate: All along the way, evaluation goes on. FINAL evaluations include their paragraph on the Mendelian traits and % work; the Family Album, Genetic Disorder presentation, and final reflection piece. Students can redo any of these final evaluations after they have been graded if they so desire! NOTES: This unit originated from an article in Science Scope, February 2001 entitled: “Genetics of Sesame Street Characters” by Susan Raye. Over the years I have revamped and added to this. Bringing it full circle has been the addition of the genetics disorder and that was spurned from the video “How do your genes fit?”. This workshop series reminded me how important it is to makes kids commit to why they think what they do, to be aware of how much informal assessment I do in the classroom every day, to make sure models (many models) are available to help students “see” what they are learning about. So, although this unit is not “new”, I have made sure to incorporate things into the lessons that help students look at their learning and think about their thinking! This unit takes about 4 weeks. GENETICS via SESAME STREET CHARACTERS Genetic Disorder Research You have just come from “The Genetic Center” and found out that in fact you have___________________________, a genetic disorder. You now need to find out the following information about it: 1. How bad is it? 2. Does it have a cure? 3. Will I die? 4. Do I have to do anything to make it better? 5. Do I have to take medication for this? (6. It is contagious?) 7. Does it make you look different? 8. Can I be around other people?> 9. Am I going to lose any body parts? 10. Does it affect any vital organs? 11. What is it? 12. Will it cause me any pain? 13. What should or shouldn’t I do? 14. Will I have to be hospitalized? 15. How can I treat it? 16. Will I be able to do everyday things? 17. How long will I live with this? GENETICS via SESAME STREET CHARACTERS Research checklist: Genetic disorder December 2008 NAME: Topic: Genetic disorder:_____________________________________ (Common name:________________________________________) Remember cite EVERY source you use.... and place all on a separate card, Card No. 8! Also, I want you to use at least TWO different sources; so you need to go beyond the Internet and find a book, article, person, or???? , to gather information from. Here’s a new one for you (I think): I want the citations annotated.... what that means is you put a little blurb after the citation telling me how you used this source. You might use the source for how you are making the presentation not info FOR the presentation! (I’ll get you an example!) Subtopics: (What you need to know about your topic) (card 1)Specific info on what the disorder is _____looks like? _____symptoms or visual signs of the disorder _____ other info? (card 2) Specific info on “how” you get this disorder (like do both parents have to have it, is it sex linked, etc.) _____The chromosome it is found on? _____sex linked? _____mutation caused by???what?? _____how is it diagnosed? _____other causes? (list here) (card 3) What it might be like to have this disorder _____specific limitations you have to live with (remember the students with Marfans Syndrome) _____life expectancy? GENETICS via SESAME STREET CHARACTERS Sites related to freak shows and circus history http://euchronia.net/sotc/ Circus music http://www.disabilityhistory.org/freak1.html http://www.bannerqueen.com/gallery.htm Side show art--- have students research a genetic disease and create a side show character based on the disease. http://www.atomicbooks.com/results.php?ep=22&cat=22 side show art http://www.newsoftheodd.com/article1006.html Tambo Tambo “cannibal” http://www.channel4.com/life/microsites/B/bornfreak/show1.html Freak show stars http://www.texasonline.net/langley/columns/freaks.htm article about modern freak shows http://www.disabilityworld.org/09-10_02/arts/freakshow.shtml disablity rights group on freak shows http://www.centralmaine.com/news/stories/030813last_fre.shtml modern freak show http://www.knddesign.com/sc/tgodgreatomi.html zebra man http://www.knddesign.com/sc/home.html sideshow central-with links to historical sideshow personality info. http://www.gibtown.com/ where side show performers live http://www.barnum-museum.org/orig/html/cast.html Barnum museum http://brightbytes.com/collection/special_people.html classic photos and info. http://rarediseases.about.com/cs/proteussyndrome/a/031301.htm elephant man Facts about genetics and albinism http://www.albinism.org/faq/children.html#Anchor-What-30408 myths about albinism http://www.genome.gov/page.cfm?pageID=10001191 FAQs about genetics and disorders http://en.wikipedia.org/wiki/List_of_genetic_disorders genetic disorders by type http://dir.yahoo.com/Health/Diseases_and_Conditions/Genetic_Disorders/ long list of disorders http://gslc.genetics.utah.edu/teachers/tindex/ online lesson plans for genetics labs http://www.noah-health.org/english/illness/genetic_diseases/geneticdis.html links to genetics sites and specific diseases will organized http://www.accessexcellence.org/RC/genetics.html access excellence genetics sites http://www.dnai.org/index.htm DNA interactive site very cool http://www.ygyh.org/ your genes your health cover genetic disease in a way that is not so complicated- good class site http://genethics.ca/topics.html genetics and ethics http://ehrweb.aaas.org/ehr/books/ genetic testing scenarios and a very concise explanation of how genetics works http://www.ornl.gov/sci/techresources/Human_Genome/posters/chromosome/ online book with a chromosome viewer that includes all the traits found on the chromosome- in color http://www.ornl.gov/sci/techresources/Human_Genome/posters/chromosome/faqs.shtml cool chart that shows how many http://www.pbs.org/wgbh/nova/baby/divide.html# mitosis and meiosis animation http://www.genetics.gsk.com/kids/index_kids.htm http://www.genecrc.org/site/ko/ko5c.htm# make a karyoptype http://www.biotechinstitute.org/pdf/Vol_10_1_2pg.pdf article on genetically engineered food http://www.boston.com/news/globe/editorial_opinion/oped/articles/2005/03/27/albino_like_me/ current event http://www.rednova.com/news/stories/5/2003/11/24/story002.html Ethics http://www.pawsweb.org/ snowflake albino gorilla GENETICS via SESAME STREET CHARACTERS http://gslc.genetics.utah.edu/- good kids discussions and activities good transcription online game http://www.childrensmuseum.org/biotech/kids.htm othe rlinks http://www.dnaftb.org/dnaftb/1/concept/index.html dna powerpoint section http://www.childrensmuseum.org/biotech/glossary.htm#biotechnology glossary http://www.childrensmuseum.org/biotech/worldofyeast.htm yeast growing in pop bottle expirement http://www.geocities.com/gm_crops/linksfor.html sites in favor of genetic engineering http://www.newscientist.com/weblinks/categories/biotech1.jsp web links http://chroma.mbt.washington.edu/outreach/genetics/classact.html http://chroma.mbt.washington.edu/outreach/genetics/download/toothpickfish.pdf toothpick fish genetics activity http://www.kumc.edu/gec/ links http://www.gig.org.uk/education.htm living with genetic disroders http://bmc.ub.uni-potsdam.de/1471-2350-2-5/ genetic disorders in Roma gypsies Links for albinism http://www.albinism.org/publications/index.html http://members.optusnet.com.au/~msafier/albinism/c19albinos.html http://kidshealth.org/kid/health_problems/skin/albinism.html good kid site http://news.bbc.co.uk/cbbcnews/hi/pictures/galleries/newsid_1764000/1764125.stm animals http://news.bbc.co.uk/cbbcnews/hi/animals/newsid_1764000/1764157.stm story with above site http://www.pantheon.org/articles/a/albino_spirit_animals.html http://www.lairweb.org.nz/tiger/albinos.html site for Tony http://www.zetatalk.com/theword/tworx339.htm animals http://news.google.com/news?hl=en&lr=&ie=ISO-8859-1&edition=us&q=albino+animals&sa=N&tab=wn google news sites http://www.altonstreet.org.uk/PILS/Albinism.htm albinism issues http://www.lunaeterna.net/popcult/scifi.htm the invisible man http://www.lunaeterna.net/popcult/classic.htm Moby Dick http://www.rickguidotti.com/sprdintr.htm positive images of people with albinism http://www.rickguidotti.com/sprd2intr.htm more images http://www.albinism.org.uk/frameset.html albinism society http://princesspale.20megsfree.com/index.html online journal of girl who has albinism http://angelblonde.20megsfree.com/frameset.html poem about being albino http://angelblonde.20megsfree.com/frameset.html poem about being albino http://members.optusnet.com.au/~msafier/albinism/c19albinos.html albinism images from 1890s Folklore http://www.earthbow.com/native/chickasaw/ghost.htm http://www.findarticles.com/cf_dls/m2386/1_113/86063329/p1/article.jhtml lab activities http://www.life.uiuc.edu/hughes/footlocker/Activities/Cheek_DNA.pdf http://whyfiles.org/teach/view.html?id=1 Why files Site links for genetics http://www.pbs.org/wgbh/harvest/ GENETICS via SESAME STREET CHARACTERS Genetic Disorder Research Evaluation Name:__________________________ Group:_________________________ Date Presented:________________ 1. Research Used class time to complete work 0 - 10 (daily reflection sheets have been turned in) _____ Cards presented to teacher at time of presentation: 8 cards (may be more) possible points 0 - 10 Used two DIFFERENT kinds of sources 0 - 10 2. Project Visual: Appealing to the eye/viewer; shows effort _____ _____ 0 - 10 _____ All necessary information is present:( 0 - 20 ) Name of disorder 5 Info on how obtained _____ 5 _____ Specifics on what it is like to “have” 5 _____ Possibilities of passing on to your children 5 _____ Extras: _____ 3. Oral Presentation: Demonstrates knowledge of subject 0 - 10 _____ Keeps eye contact with the audience 0 - 5 _____ Speaks clearly with appropriate volume 0 - 5 _____ Show enthusiasm for subject/project 0 - 5 _____ 4. Final Reflection (written) What is the best thing about your project, convince me! 0 - 15 Possible points out of 100 _____ _____