Download Chapter 12 Review

Chapter 12 Review
Name________________
Who did what?
Who proposed that heredity factors carried on chromosomes?______________________
Who hypothesized chromosomes responsible for heredity?________________________
Who called these small parts “genes”?___________________________________________
Who’s work was rediscovered?_________________________________________________
Who was the first to see chromosomes?__________________________________________
Who proposed the chromosome theory?_________________________________________
Genetic Disorders: (match)
Turners syndrome
- occurs mostly in African Americans
Klinefelter’s syndrome
- contains an extra 21st chromosomes
Huntington’s disease
- degeneration of muscles
PKU
- excessive mucous produced in the lungs
Hemophilia
- only one X chromosome
Sickle Cell Anemia
- contains an XXY
Cystic fibrosis
- failure of brain to develop in infancy
Tay Sachs
- sex-linked blood clotting disorder
Down syndrome
- destroys the central nervous system
Muscular Dystrophy
- deterioration of brain tissue
Problems:
A man who is not bald marries a women who is heterozygous for baldness. What is the chance of having a
bald child?
A mother with Type AB blood marries a man with Type B blood. What are the genotypes of the parents if
one child has Type AB and the other with Type A?
In humans the gene from normal blood clotting, H, is dominate to the gene for hemophilia, h. This is a sexlinked trait found on the X chromosome. A woman with normal blood clotting has four children. They are a
normal son, a hemophiliac son, and two normal daughters. The father has normal blood clotting. What is
the probable genotype for each member of the family?
This is a sex-linked trait. A normal clotting female whose father was a hemophiliac, marries a man who
has normal clotting blood. What are the expected genotypic and phenotypic ratios?
Windows peak (W) is dominant to the No widows peak (w). A science class wanted to find the frequency of
the 2 alleles in their school’s population. A survey showed the following results: 388 non widows peak
and 812 who had a widows peak. Find the following information, show the math you have to do - you
may use a calculator to actually do the math.
Use these equations: p2 + 2pq + q2 = 1 and p + q = 1 (answers to nearest .001)
frequency of homozygous recessive ___________
frequency of gene (w) __________
frequency of gene (W) __________
frequency of heterozygous genotype ___________
number of students that are heterozygous _________ (nearest whole student)
A.
B.
----------------------C.
________________________ What is the name of the area marked C?
________________________ What is the name of the area marked B?
________________________ What is the name of the area marked A?
____________________ Name a trait found in humans that the gene for it would be located in area C?
____________________ Name a trait found in humans that the gene for it would be located in area B?
____________________ Name a trait found in humans that the gene for it would be located in area A?
The chromosome on the right is called the ________________ chromosome.
The chromosome on the left is called the ________________ chromosome.
A scientist wishes to find out how many people in the United States have attached earlobes. Will the
scientist check the ears of every person in the country? Explain what he would do.
_______________________________________________________________________
_______________________________________________________________________
A set of fraternal twins separated at birth and reared in different environments was studied to determine
to what extent environmental factors shape development. What problem do you see in the reliability of
such a study?
_______________________________________________________________________
Define multiple alleles. What alleles are present for blood types? Name the blood types.
_______________________________________________________________________
_______________________________________________________________________
Explain why skin color is considered a polygenic trait?
_______________________________________________________________________
Explain why baldness is a sex-influenced trait and describe the inheritance pattern.
_______________________________________________________________________
_______________________________________________________________________
_______________________________________________________________________
Define nondisjunction
_______________________________________________________________________
Give the name of the following disorders:
XXY = ________________________
trisomy #21 = ________________________
XXX = ________________________
XO = _______________________________
What are the following:

amniocentesis ___________________________________________________________
_________________________________________________________________________

chorionic villi biopsy _______________________________________________________
_________________________________________________________________________
ultra sound ______________________________________________________________
___________ ______________________________________________________________
genetic screening _________________________________________________________
_________________________________________________________________________
genetic counseling ________________________________________________________
_________________________________________________________________________
erythroblastosis fetalis _____________________________________________________
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

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
_________________________________________________________________________
Rhogam shot ____________________________________________________________
_________________________________________________________________________
Classify each of these genetic disorders under its proper heading.
PKU
Down syndrome
hemophilia
sickle-cell anemia
Klinefelter’s syndrome
baldness
Genetic Disorders on autosomes
Nondisjunction
polydactaly
Turner’s syndrome
color blindness
Sex linked or Sex influenced traits
Explain fully why type A blood cannot be transfused into a type B person.
_________________________________________________________________________
_________________________________________________________________________
_________________________________________________________________________
For erythroblastosis fetalis to occur, what is the Rh factor for the mom, dad and baby?
Mom __________
Dad __________
Baby ___________
Can Rh positive blood be transfused into an Rh negative person? _______