Download Yougang Mao Page 1 Yougang Mao 502 Cato St., Pittsburgh, PA

Yougang Mao
502 Cato St., Pittsburgh, PA 15213
Tel: 626-943-0883(Cell), e-mail: [email protected]
OBJECTIVE
A research and development position that requires my interdisciplinary experiences in chemistry,
biophysics, biochemistry and chemical engineering and my expertise in inter- and intra-molecular
interaction and molecular dynamics to help design of new materials and drugs, and my expertise
in NMR, ESR UV instrumentation.
ACCOMPLISHMENT
Crucial contributions include two new formulas which can be used to study inter- and intramolecular interaction by NMR spin lattice relaxation time and REDOR experiments., the icesurface adsorption enhanced colligative model that can be used to detect the protein
concentration on ice surface, a new process for making ice that burns in NMR tube in a week,, an
ESR method to study Arrhenius parameters of radical and their change with medium environment,
received three research grants when I was in China as an associate professor, more than 20 peer
reviewed articles and a news note that the science writer of American Chemical Society
distributed to journalists as a news.
PROFESSIONAL EXPERIENCE
University of Pittsburgh, Pittsburgh, Pennsylvania
Visiting Research Associate
November 2012 to present
Study the interactions between cation and anion in ionic liquid with NMR diffusion and conductivity
measurements
 Study the correlated motion of cation and anion and its effect on ionic liquid conductivities and
gas absorptions
 Identify the driving force of correlated motion of cation and anion to help molecular design
 Develop a method that makes the NMR diffusion measurements be used to study chemical
reaction process
California State University Los Angeles, Los Angeles, California
Research Associate
January 2003 to July 2012
Antifreeze protein, anti cancer drug delivery and gas hydrate studies
 Study the interaction between protein and ice surface and its relation to antifreeze function of
the protein
 Develop the NMR experimental and theoretical methods that can be used to study the
interaction between protein and ice surface
 Propose ice-surface adsorption enhanced colligative model to detect the protein concentration
on ice surface
 Study the interaction between drug and hydrogel by ESR method and its relation to drug
Loading capacity
 Produced gas hydrate in a sealed NMR tube in one week. Conventional technology requires
one year to produce this hydrate in NMR tube.
Jilin University, Changchun, P.R. China.
Associate Professor and Principal Investigate
October 1996 to January 2003
Yougang Mao
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Lecturer
October 1987 to October 1996
 The study of the relation between bulk polymerization kinetics and molecular weight
distribution.
 Molecular recognition in vesicles.
 Dynamic NMR study of polyaminocarboxylic acid metal complexes
 Taught NMR, ESR and polymer reaction statistics
Jilin Agricultural University, Changchun, P.R. China.
Assistant Professor
September 1982 to October 1984
 Synthesis and property of some sieve zeolites.
 Taught general chemistry and laboratory classes.
SKILLS
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NMR (Bruker Avance DRX 400 and 600WB) and ESR (Bruker EMX X Band)
routine operation and maintenance of magnets and spectrometers. pulse program.
1D/2D and micro image NMR experimental design and spectral analysis
Insight II in a linux computer to calculate the interaction between protein and ligand
Protein expression, site directed spin labeling and purification
Knowledge of HPLC FTIR,UV/VIS and MS
RESEARCH Grants AWARDED AS A PRINCIPAL INVESTIGATOR (PI)
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The Special Funds for Major State Basic Research Project (G1999064803) 1999-2003, China.
Grants of National Natural Science Foundation of China (29674011) 1997-1999,.
Grants of National Natural Science Foundation of China (29734130) 1998-2002,.
EDUCATION/TRAINING
PhD. in Chemistry, Jilin University, P. R. China.
M.S. in Chemistry, Jilin University, P. R. China.
B.S. in Chemistry, Jilin University, P. R. China.
PUBLICATIONS IN REFERED JOURNAL AND PRESENTATION
Yougang Mao
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SECLECTED PUBLICATIONS
1. Yong Ba*, Yougang Mao, Luiz Galdino, Zorigoo Gunsen; Effects of a Type I Antifreeze Protein
(AFP) on the Melting of Frozen AFP and AFP+Solute Aqueous Solutions Studied by NMR MicroImaging Experiment
Journal of Biological Physics, 2013 39 131–144.
2. Yougang Mao, Myongho Jeong, Tieli Wang, Yong Ba*, Threonine side chain conformational
population distribution of a type I antifreeze protein on interacting with ice surface studied via 13C–
15N dynamic REDOR NMR
Solid State Nuclear Magnetic Resonance, 2011, 39, 7–13.
3. Yougang Mao, Wei Lin, Yong Ba*
Antifreeze Protein NMR Sensor to Detect Water Molecular Reorientation In the Surface of Ice
Journal of Chemical Physics, 2009, 131, 101102.
4. Xiangli Liu, Yougang Mao, Errol V. Mathias, Collin Ma, Osmundo Franco, Yong Ba*,
Julia A. Kornfield, Tieli Wang, Lijun Xue, Bing-Sen Zhou, Yun Yen; Study the Property of Doubleended Fluoroalkyl Poly(ethylene glycol) Hydrogel as a Depot for Hydrophobic Drug Delivery Using
Electron Paramagnetic Resonance Technique and cell proliferation assay
Journal of Sol-Gel Science and Technology 2008, 45, 260-278.
5. Yougang Mao, Yong Ba*; Insight into the Binding of Antifreeze Proteins to Ice Surface via 13C Spin
Lattice Relaxation Solid State NMR
Biophysical Journal, 2006, 91, 1059-1068.
6. Yougang Mao, Yong Ba*
Ice-Surface Adsorption Enhanced Colligative Effect of Antifreeze Proteins in Ice Growth Inhibition
Journal of Chemical Physics, 2006, 125, 911021-5.
7. Raffie Avakian, Yougang Mao, Danny Chagolla, and Yong Ba*;Temperature-Gradient Assisted
Gas-Dissolved Liquid-Phase Synthesis of Clathrate Hydrates
Energy & Fuels 2006, 20, 1197-1200.
8. Yougang Mao*, Min Wang, Bai Yang, Bogeng Li, Fei Li, and Jiacong Shen
Effect of Medium Environment on the propagating Step in Free radical Polymerization
J. Phys. Chem. B, 2002, 106(18), 4602-4607.
9. Min Wang, Yougang Mao*, Yanying Lu , Renfei Yang, Fei Li, Jiacong Shen.
The effect of Chain Length on MMA Free Radical Polymerization
Chinese Chemical Letter, 2001, 12(11), 1041-1042.
10. Yougang Mao*, Ruifang Song, Yingguang Zheng, Jiacong Shen,
The Identification of ESR Spectra and Conformation of Propagating Radical of
PolyStyrene and Their Change with Medium Environment
Macromolecules, 1994, 27(23), 6746.
11. Yougang Mao*, Ruifang Song, Yingguang Zheng, Jiacong Shen,
The Study of ESR Spectra in solid state and high viscosity solution for Propagating Radical
of Polystyrene
Chinese Chemical Letters, 1994 5(8) 695.
12. Rui Fang SONG*, You Gang MAO, Fei LI, Song Yan QIN
NMR Study of Zn2TTHA and Other Complexes with TTHA
Gaodeng Xuexiao Huaxue Xuebao,(Chemical Journal of Chinese University) 1995, 16(9), 1436.