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Biochemistry: Unit 3 Plan Test Date: _______________ Essential Concepts and Skills Reading 1. Atomic Structure a. The structure of an atom and its properties: protons: positive part of the atom found in the nucleus. It is the atomic number and it is most of the mass of the atom. neutrons: neutral part of the atom found in the nucleus. It is important for isotopes. electron: the negative part of the atom (found orbiting the nucleus). It is important for bonding. b. Periodic properties: what it means to be organic (contains carbon). c. Bonding – there are three main types of bonds: ionic: the giving and taking of electrons covalent: the sharing of electrons (most organic compounds are this type). Hydrogen bonds: weak forces between hydrogen and other elements (see below). pp 35-39 2. Diagram the structure of a water molecule and describe hydrogen bonding between water molecules. a. A water molecule contains two hydrogen atoms bonded to an oxygen forming a molecule that looks like Mickey Mouse ears. b. The partially positive hydrogen atoms on one water molecule are attracted to the partially negative oxygen atom or another water molecule. This attraction is called a hydrogen bond. c. Hydrogen bonding causes water molecules to be attracted to one another. pp 40-41 diagram p 41 3. Describe three ways that life on Earth depends on hydrogen bonding between water molecules. a. Water will move upwards in the small tubes found in the roots and shoots of plants, so plants can get water and nutrients through their roots (capillary action). b. Water is able to absorb large amounts of heat so lakes and oceans stabilize air and land temperatures (high heat capacity). c. Water is able to dissolve many substances so the water inside and outside of cells can carry nutrients into and around cells and waste away from cells. d. Water absorbs heat when it evaporates allowing organisms to get rid of excess heat. e. In the solid from, ice floats. This prevents lakes and oceans from freezing solid. f. Most of the water in our body is absorbed through our large intestine. p. 41 4. Explain the importance of pH to organisms. a. The pH scale goes from 0 to 14; 7 is neutral, below 7 is acidic and above 7 is basic. b. Every cell has a particular pH at which it functions best and maintains homeostasis. c. Living organisms can only tolerate small changes of pH in their environment. pp 42-43 5. Explain how cells make a variety of macromolecules from a small set of monomers. a. A polymer is a large molecule (macromolecule) that is formed from smaller molecules (monomer) bonding together in a long chain. b. Proteins are macromolecules. Ribosomes make proteins by joining amino acids together in a chain. p. 45 6. Give the function of these groups of macromolecules: carbohydrates, lipids, proteins and nucleic acids. a. Substances such as carbohydrates, lipids, proteins and nucleic acids are called organic compounds because they contain carbon. b. Carbohydrates provide organisms (cells) with energy. c. Lipids store energy and do not dissolve in water; lipids make up cell membranes. d. Nucleic acids store the cell’s information in the form of a code. DNA forms the genetic code. e. Some proteins are structural (hair, nails - skeletal system) while other function in transport (hemoglobin – circulatory system), movement (muscle fibers – muscular system), defense (antibodies – immune system), and regulation of cell functions (hormones and enzymes – endocrine system). pp 44-48 pp 972-973 7. Use the example of enzymes to describe how a protein’s function depends on its specific conformation. a. Enzymes are proteins with a specific shape. b. Enzyme’s function to speed up chemical reactions. c. Enzymes can be used over and over again. d. The substrate is the substance the enzyme is working on. e. The active site is the place on the enzyme where the substrate attaches to the enzyme. f. Each enzyme has a definite three-dimensional shape which allows it to recognize and bind with the substrate (like 2 puzzle pieces). g. Enzymes in our digestive system break down polymers (starch) to monomers (sugar). pp 51-53