Download C. African American

NAME _____________________________ f12
Chapter 14 -GENETIC DISORDERS TEST MODIFIED
(2 points each)
MATCHING:
Match the genetic disorder with its description.
________
Change in hemoglobin gene causes red blood cells to
change shape causing circulatory problems
A.
B.
C.
D.
E.
F.
PHENYLKETONURIA
CYSTIC FIBROSIS
HUNTINGTON’s
COLORBLINDNESS
HEMOPHILIA
SICKLE CELL DISEASE
________
Degenerative brain disorder caused by extra CAG repeats
in the gene code whose symptoms appear around middle age
which results in nursing home care and eventually death
________
Inability to distinguish between certain colors
(especially red and green)
_______
Mutation in a blood clotting protein so individuals can’t stop
bleeding if injured
_______
Mutation in gene that breaks down the amino acid phenylalanine
which accumulates in their brain and persons become retarded if
they eat foods containing phenylalanine.
_______
Defect in ion channels which transport Cl- ions causing mucous to build up
in lungs and digestive organs
*
*
*
_______
*
*
*
*
*
*
*
*
Mutation in muscle proteins that gradually weakens and
destroys muscle tissue
_______
Enzyme defect that causes lipids to build up in the brain;
Results in blindness, retardation, and death by age 5
_______
Defect in bone formation resulting in a person with a
normal size head and torso, but short arms and legs
_______
Syndrome in which a person has an extra #21 chromosome
causing mental retardation and often heart defects
_______
Females with only one X chromosome (XO)
_______
Males with extra X chromosomes (XXy, XXXy, XXXXy)
*
*
*
*
A. TURNER SYNDROME
B. DOWN SYNDROME
C. TAY-SACHS
D.KLINEFELTER SYNDROME
E. ACHONDROPLASIA
F. DUCHENNE MUSCULAR
DYSTROPHY
MULTIPLE CHOICE:
Tell how each of the following disorders is inherited:
_______
Achondroplasia
A. autosomal dominant
B. autosomal recessive
C. autosomal COdominant
D. X-linked recessive
E. nondisjunction
________
Sickle Cell Disease
A. autosomal dominant
B. autosomal recessive
C. autosomal COdominant
D. X-linked recessive
E. nondisjunction
_______
Hemophilia
A. autosomal dominant
B. autosomal recessive
C. autosomal COdominant
D. X-linked recessive
E. nondisjunction
________
Tay-Sachs disease
A. autosomal dominant
B. autosomal recessive
C. autosomal COdominant
D. X-linked recessive
E. nondisjunction
_______
Down syndrome
A. autosomal dominant
B. autosomal recessive
C. autosomal COdominant
D. X-linked recessive
E. nondisjunction
________
Colorblindness
A. autosomal dominant
B. autosomal recessive
C. autosomal COdominant
D. X-linked recessive
E. nondisjunction
_______
Duchenne Muscular Dystrophy
A. autosomal dominant
B. autosomal recessive
C. autosomal COdominant
D. X-linked recessive
E. nondisjunction
________
Phenylketonuria (PKU)
A. autosomal dominant
B. autosomal recessive
C. autosomal COdominant
D. X-linked recessive
E. nondisjunction
_______
Cystic Fibrosis
A. autosomal dominant
B. autosomal recessive
C. autosomal COdominant
D. X-linked recessive
E. nondisjunction
________
Turner syndrome
A. autosomal dominant
B. autosomal recessive
C. autosomal COdominant
D. X-linked recessive
E. nondisjunction
_______
Klinefelter syndrome
A. autosomal dominant
B. autosomal recessive
C. autosomal COdominant
D. X-linked recessive
E. nondisjunction
________
Huntington’s disease
A. autosomal dominant
B. autosomal recessive
C. autosomal COdominant
D. X-linked recessive
E. nondisjunction
MULTIPLE CHOICE:
Put the letter of the answer that best completes the statement on the blank at the left.
_______ In humans an XX genotype makes you a ___________________
A. male
B. female
C.
D. carrier
________
________
________
__________________ cell mutations happen in sperm or eggs and can be passed on to the
offspring.
A.
B. somatic
C. germ
D. allele
____________________ mutations cause death, often before birth.
A.
B. X-linked
C. Germ cell
D. Lethal
__________________ cell mutations happen in body cells so they affect the organism itself,
but are NOT passed on to offspring.
A. Gamete
B. Somatic
C. Germ
D.
_______ In humans an Xy genotype makes you a ____________________.
A. male
B. female
C.
D. carrier
________
A gene that is carried on an X or Y chromosome is called ______________________.
A.
B. sex linked
C. autosomal
D. lethal
________
The failure of homologous chromosomes to separate during meiosis is called ______________
A. nondisjunction
B.
C. crossing over
D. synapsis
________ A family record that shows how a trait is inherited
over several generations is called a _____________
A. karyotype
B. Punnett square
C. pedigree
D.
________ A person that has one copy of a recessive autosomal allele and does not express the trait but can
pass it on to his/her offspring is called a __________________.
A.
B. carrier
C. hemophiliac
D. gene marker
________
_______________________ can be carriers for AUTOSOMAL RECESSIVE disorders.
A. Only males
B. Only females
C. Both males and females
________
_______________________ can be carriers for X-LINKED RECESSIVE disorders.
A. Only females
B. Only males
C. Both males and females
________
A human cell with 3 copies of a chromosome would have 47 chromosomes instead of 46.
This condition is called ____________________.
A. monosomy
B.
C. tetrads
D. trisomy
________
_____________________________ twins have identical DNA.
A. monozygotic
B. dizygotic
C. fraternal
D.
________
This picture of an organism’s chromosomes is called a
______________________
A. pedigree
B. Punnett square
C. karyotype
________
The chromosomes that DO NOT determine sex are called ____________________
A. sex chromosomes
B. autosomes
C.
D. pedigree partners
________
Which parent determines the sex of the baby?
A. father
B. mother
________
The dense region in the nucleus of female cells that forms when one of the X chromosomes is
randomly inactivated is called a _____________________ body.
A. autosomal
B.
C. nucleolus
D. Barr
________
Turner syndrome is an example of a _____________________ disorder.
A. trisomy
B. monosomy
C. somatic cell mutation
________
X-linked recessive disorders show up more frequently in ____________________.
A. females
B. males
________
Sickle cell disease is found more frequently in __________________________ populations.
A. Jewish
B. Caucasians
C. African American
________
Tay-Sachs disease is found more frequently in_________________________ populations.
A.
B. Caucasion
C. African American
D. Jewish or Middle Eastern
________
Cystic fibrosis is found more frequently in _______________________ populations.
A.
B. Caucasion
C. African American
D. Jewish or Middle Eastern
Match the symbol letter with the correct description
Which member of this family shows the trait?
A
B
C
D
E
F
Which represents a male is a carrier for this trait?
A
B
C
D
E
F
A and E in the diagram above are __________________
A. normal females
B. normal males
C. diseased males
D. diseased females
B and D in the diagram above are __________________
A. normal males
B. carrier males
C. diseased females
D. carrier females
*
*
*
*
*
*
*
*
*
*
*
*
*
BONUS
Which genetic disorder can be found in a pedigree showing the royal families of Europe?
A. Huntington’s disease
B. hemophilia
C. colorblindness
D. Achondroplasia
What trait changes in female cats as a result of the production of Barr bodies?
A. length of whiskers
B. length of tail
C. length of hair
D. spot color
*
*