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Biology B – Fetsco Name: _____________________________________ Chapter 10 – Cell Growth and Division Limits to Cell Size Cells can grow by increasing in ______________, but eventually a cell needs to divide. Why do you think a cells needs to divide after is reaches a certain size? A cell needs to divide as it grows larger because ….. 1. 2. Cell Division – the process by which one cell divides to form two new ________________________________________________. _________________________ reproduction: o Growth of an organism o _________________ ___________________ __________________ Repair of an organism Replacement of lost or damaged cells o Ex. ________________________________________________ Reproduction of an entirely new organism A single cell or a group of cells each duplicates their genetic information, and splits into _______________________________________________________. Offspring are ________________________________ to their parents. Ex. paramecium, amoeba, sea stars Plants can reproduce asexually. Can you think of an example of this? Biology B – Fetsco Name: _____________________________________ __________________________ reproduction: o Occurs for one reason - ___________________________________________ o ____________ parents are involved in the production of offspring. Genetic material (DNA) from each parent combines to form the offspring. o Involves the union of sex cells called ____________________________. o These sex cells are formed in a ___________________________________ than the cells formed by asexual reproduction. Plants can also reproduce sexually. Can you think of an example of this? The Process of Cell Division About ________________________________ cells are dividing in your body right now. Around ______________________________________ aren’t dividing, but are carrying out all the other activities your body needs to survive. The most important aspect of any type of cell division is the reproduction of the ________________. o Most of the time, DNA exists as a long mass of fibers that are too small to see under a light microscope. These long fibers are called _______________________, which is a combination of DNA and protein molecules. When the cell is ready to divide, the chromatin condenses, and is now called a ___________________________________. The DNA in this condensed form is now visible with a light microscope. Biology B – Fetsco Name: _____________________________________ DNA condenses into chromosomes because chromosomes ________________________________ ________________________________________________________________________________. Humans have ______________________ chromosomes. Other organisms have different numbers of chromosomes. For instance, some types of raspberries have 98 chromosomes, a pea plant only has 14, and a rat has 42. Before a cell can divide, it has to _____________________________________________. Why would a cell need to duplicate chromosomes before it divides? Label the parts of the diagram below as we talk about them in class. Biology B – Fetsco Name: _____________________________________ The ____________________________________ controls how often a cell divides. The length of the cell cycle varies depending on the _______________________________________. o Some human cells go through the cell cycle around _____________________________. o Ex. Some human cells, like ____________________________, don’t divide at all. The cell cycle has 2 major stages: 1. Interphase Interphase is composed of three phases: 2. Mitosis Interphase G1 S G2 Mitosis _____________________________________________________ _____________________________________________________ _____________________________________________________ Biology B – Fetsco Name: _____________________________________ Mitosis is when the _____________________________________________. The purpose is to provide two cells that are __________________________ identical. • To achieve this, the chromosomes must go through a series of movements, known as the ________________________ of mitosis. • These movements are guided by ______________________________________, or spindles. • Spindle fibers extend from two structures called ____________________________. Although it is a continuous process, scientists divide mitosis into _______________ main phases. Human skin cell -- Total cycle takes around ________________ to complete. Interphase G1 S G2 M 9.9 hours 6.2 hours 3.3 hours 1.9 hours 9.7 hours 5.8 hours 3.9 hours 2.3 hours 10.1 hours 5.5 hours 3.5 hour 2.1 hours 10.1 hours 4.9 hours 3.1 hours 1.8 hours 10.3 hours 5.4 hours 3.6 hours 2.0 hours 9.9 hours 6.1 hours 3.7 hours 1.9 hours Average = Average = Average = Average = %= %= %= %= Biology B – Fetsco Name: _____________________________________ Cytokinesis: _____________________________________________________________________ Plants vs. Animals Regulating the Cell Cycle Cells grown in the lab will divide until they come into contact with _____________________________. They do this in our bodies as well. When you have a cut, your skin cells at the edge of the injury will begin to divide rapidly until the cut is healed, at which time cell division ________________________ and everything returns to normal. Proteins called ____________________________ help to regulate the cell cycle. Cells also end their life cycle in one of two ways: 1. They die due to ______________________________________________. 2. Apoptosis: _________________________________________________________________________ ____________________________________________________________________________________ • A __________________________ is an abnormal growth of cells. • This happens when cells are ________________________ out of control. Proteins in our body are supposed to control the cell cycle, telling cells _____________________________________________________, but when something with this system goes wrong, a cell may reproduce at the wrong time, or the wrong place. • Tumors can be ________________________ or they can be _________________________. • Malignant tumors are a mass of abnormal cells that can ______________________ ______________________________ to the surrounding tissue. • These tumors are considered _____________________________. • Benign tumors are an abnormal mass relatively ________________________ cells. • Generally, they do not cause harm to the body, but sometimes they are ____________________________ as a precaution. Biology B – Fetsco Name: _____________________________________ • __________________________ is defined as a collection of cells that are dividing out of control and interfere with the functioning of the ________________________ _________________________. • These cells compete with ________________________________________ for food, oxygen, and blood supply. • One of the most dangerous characterisitics of cancer cells is called _______________________________. This is when cancerous cells can break of the tumor and travel to other parts of the ___________________________. • This is very dangerous because then ____________________________ can form in other parts of the body. • Cancer is caused by defects in the genes that regulate cell growth and division. Sources of these defects include: • _____________________________ - changes in DNA that are inherited • _____________________________-cancer-causing chemicals • Examples: cigarette smoke, UV light exposure • _____________________________ - some types are associated with cancer. • Examples: Human Papilloma virus (HPV) associated with cervical cancer Biology B – Fetsco Name: _____________________________________ Cancer Treatments: • ______________________________ of the tumor and/or structures and organs associated with the tumor. • _______________________________ - exposure of areas with tumors to hight energy radiation. • ________________________________- kills rapidly dividing cells with prescription drugs Cancer cells are rapidly dividing, but so are other cells in the human body. What might be some side effects of using radiation or chemotherapy? Cell Differentiation Living things go through several stages of development, from zygote to embryo to adult. Differentiation: ________________________________________________________________________ The process of differentiation determines what type a cell becomes. Ex. Read pages 294 -297 in your book and fill in the following information: Definitions: Totipotent: Blastocyst: Pluripotent: Stem Cell: Multipotent: Fill in the chart below: Potential Benefits Ethical Issue Biology B – Fetsco Name: _____________________________________ Chapter 11.4 - Meiosis Humans have __________ chromosomes, or 23 ___________________________________________(n). -_______________________________-matching chromosome pairs, same shape and size but not genetically identical -One homologous chromosome from each _______________________. -These are not the same as ________________________________________= not identical copies -Homologous chromosomes control the _______________________, but one might have the gene for blue eyes while another might have a gene for green eyes. A _____________________________ displays all of an organism’s chromosomes, arranged by size. Chromosome pair 23 are ____________________________________________________. XX= XY= The X and Y chromosomes each contain different genetic information. Biology B – Fetsco Name: _____________________________________ Diploid(2n)___________________________________________________________________________ Ex. Humans = 46 Haploid(1n)___________________________________________________________________________ Ex. Humans have 23 chromosomes in their sex cells, or __________________ (sperm/egg) -Haploid cells are produced through ____________________________ egg + sperm=zygote + = Phases of Meiosis Meiosis has _____________ main parts: 1. ___________________________________ - homologous chromosomes are separated from each other 2. ___________________________________- sister chromatids are separated from each other to form 4 haploid daughter cellss Meiosis ________________________________________________ in two ways: 1. The way in which ______________________________________________ in metaphase I is completely up to chance 2. _____________________________________ - exchange of genetic material between homologous chromosomes during prophase I -in tetrads -this produces chromosomes with _____________________________________ __________________________ which is called genetic recombination -One chromosome can contain hundreds of genes so one crossing over even can transfer _________________________________________________ Biology B – Fetsco Name: _____________________________________ Mitosis Meiosis Asexual reproduction – to ___________________ _______________________ _____- to reproduce _________________________________________ new, genetically different organisms _________________________________________ 1 cell _____________________________ to make 1 cell divides twice to produce ______________ two identical cells with a full set of ________________________, each with ½ the ______________________________ number of chromosomes Occurs in sex organ cells (___________________ Occurs in ________________________________ and _______________________)