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AS PE for OCR Teacher Resource File 2nd Edition 3.I.1 3 The cardiovascular and respiratory systems Chambers of the heart – answers 1. © Pearson Education Ltd 2008 79 3 The cardiovascular and respiratory systems 3.I.2 AS PE for OCR Teacher Resource File 2nd Edition The conduction system of the heart – answers 1. Adapted from: Seeley and Tate 80 © Pearson Education Ltd 2008 AS PE for OCR Teacher Resource File 2nd Edition 3.I.3 3 The cardiovascular and respiratory systems Cardiac cycle – answers Briefly describe, in order, the events during the cardiac cycle in the diagrams below. Diastole Relaxation/passive filling phase lasting 0.5 seconds. Deoxygenated blood enters right atria from superior and inferior vena cavae.. Oxygenated blood enters left atrium from pulmonary veins. Rising pressure of blood against AV valves forces blood through into ventricles. Past tricuspid valve on the right side of the heart. Past bicuspid valve on the left side of the heart. Volume of blood after filling is termed end diastolic volume (EDV). Atrial systole Contraction of left and right atria. Increased pressure in atria forces the remaining blood into the left and right ventricles. © Pearson Education Ltd 2008 81 3 The cardiovascular and respiratory systems AS PE for OCR Teacher Resource File 2nd Edition Ventricular systole Contraction of both left and right ventricles. Lungs Lungs Body Increases ventricle pressure, forcing blood out of both ventricles (stroke volume). Right ventricle forces blood out of pulmonary valve into pulmonary artery to the lungs. Left ventricle forces blood out of aortic valve into aorta to the body tissues. A reserve volume of blood may be left in ventricles (ESV). Tricuspid and bicuspid valves remain shut. Aortic and pulmonary valve close after ventricular systole to prevent blood flow back into ventricles. Next diastole phase begins. 82 © Pearson Education Ltd 2008 AS PE for OCR Teacher Resource File 2nd Edition 3.I.4 3 The cardiovascular and respiratory systems Distribution of cardiac output at rest: answers ‘Approximately 5 litres of blood is pumped out of the heart every minute.’ • Look at the distribution of cardiac output during resting conditions in the diagram below. • To simplify the diagram, let us split all the divisions into: (a) muscles (b) organs (liver, kidneys, heart, brain and others). Muscles (20%) 1000ml Liver (27%) 1350ml Heart (4%) 200ml Skin (6%) 300ml Kidneys (22%) 1100ml Brain (14%) 700ml Other (7%) 350ml 1 Where is the greatest percentage of cardiac output distributed during resting conditions? Greatest % distributed to organs. Only 20% distributed to muscles. 2 In relation to their overall mass compare the percentage of cardiac output distributed to the kidneys, and that distributed to the muscles. % distributed to kidneys is much the same as muscles and yet kidneys are very small compared with muscle mass. 3 Why is the distribution of cardiac output to muscles so low during resting conditions, despite the larger surface area of muscle? During rest muscles are mostly inactive and do not require a large % of cardiac output to supply the oxygen for their energy demands. © Pearson Education Ltd 2008 83 3 The cardiovascular and respiratory systems 3.I.5 AS PE for OCR Teacher Resource File 2nd Edition Distribution of cardiac output during exercise – answers 1. Fill in the missing spaces with the following words: supply cardiac output oxygen demand increased During exercise the muscles’ demand for oxygen increases in line with exercise intensity. If the supply of oxygen is to be met then the % of cardiac output distributed to the working muscles will need to be increased. 2. Show your understanding of the redistribution of cardiac output during exercise by filling in the spaces to label the graph below. Use the labels provided. 80% REST MUSCLES ORGANS EXERCISE 20% Redistribution of cardiac output from rest to exercise Cardiac output Q Approx 80% Q MUSCLES ORGANS Approx 20% Q AT REST DURING EXERCISE Intensity 84 © Pearson Education Ltd 2008 AS PE for OCR Teacher Resource File 2nd Edition 3.I.6 3 The cardiovascular and respiratory systems Stroke volume response to exercise – answers 1. Stroke volume is determined by four main factors: • Venous return volume (Starling’s Law of the Heart) • ventricular stretch (EDV) • ventricular contractility/force of contraction (ESV) • and pulmonary artery pressure. Stroke volume (SV) increases with exercise intensity 2. What happens to SV as exercise intensity increases? SV increases with increase in intensity but only up to exercise intensities between 40– 60% of an individual’s maximal working capacity. 3. What happens to SV before exercise intensity approaches maximal working capacity? After this, stroke volume is thought to plateau or fall slightly. 4. Why does SV not continue to increase towards maximal capacity as exercise intensity increases? Heart rate increases as exercise intensity increases; therefore there is less time for diastole/venous return to fill the heart. The physical size of the heart also limits/prevents SV from continuing to increase. SV changes with heart rate to ensure the most efficient supply of cardiac output to the working muscles. 5. What is the benefit of an increased SV during exercise? Increased SV increases Q and therefore increases supply of O2 to the working muscles, increasing aerobic endurance and delaying fatigue. © Pearson Education Ltd 2008 85 3 The cardiovascular and respiratory systems 3.I.7 AS PE for OCR Teacher Resource File 2nd Edition Heart rate, stroke volume and Q response to changes in posture and exercise – answers 1. What happens to heart rate (HR) as exercise intensity increases? HR increases in line with exercise intensity. 2. What happens to SV from supine to sitting and then to standing? Why? SV decreases from supine to sitting, and decreases further to standing. Blood pooling does not occur in the supine position so VR is easily returned to the heart. In sitting and standing VR has to return against gravity, increasing blood pooling, which reduces VR and therefore SV (Starling’s Law). 3. What happens to cardiac output (Q) from supine to sitting and standing? Q is a product of SV and therefore decreases in line with SV from sitting and standing. 4. What happens to HR, SV and Q from walking to jogging and running? HR and SV increase and consequently increase Q as exercise intensity increases. 5. Why does the swimmer have the highest SV? Swimmer is in a supine position so there is less blood pooling in the legs. 6. Why does the cyclist have the lowest SV from the three exercise activities? Cycling position causes the most blood pooling, and fewer muscles are active, reducing muscle pump action. 86 © Pearson Education Ltd 2008 AS PE for OCR Teacher Resource File 2nd Edition 3.I.8 3 The cardiovascular and respiratory systems Resting cardiac output, stroke volume and heart rate – answers 1. Fill in the missing information to provide definitions and volumes for HR, SV and Q. Heart Rate (HR) The number of ventricular contractions in one minute. Untrained 70bpm Trained 50bpm Stroke Volume (SV) The amount of blood ejected from the heart each time the ventricles contract Untrained 71ml Trained 100ml Cardiac Output (Q) The amount of blood ejected from the heart in 1 minute Untrained 4970ml (4.97 litres) Trained 5000ml (5 litres) Cardiac output (Q) SV × HR © Pearson Education Ltd 2008 87 3 The cardiovascular and respiratory systems 3.I.9 AS PE for OCR Teacher Resource File 2nd Edition Stroke volume – answers 1. End-Diastolic Volume EDV (before/filling) The volume of blood in the ventricles when it has completed its relaxation phase. End-Systolic Volume ESV (after) The volume of blood remaining in the ventricles when it has completed its contraction phase. Stroke Volume SV (difference) The volume of blood ejected from the heart ventricles per beat. 2. EDV – ESV = SV 3. (See below in the glasses.) 4. Only up to 40–50% of the blood in the ventricles is pumped out at rest. 5. Heart has a reserve volume (ESV), which can be used during exercise to increase SV. At rest: Before After SV EDV = 130ml ESV = 60ml SV = 70ml – = Notice that around 40–50% of the blood in the ventricles is pumped out at rest. During exercise: Before After SV EDV = 130ml ESV = 10ml SV = 120ml – 88 = © Pearson Education Ltd 2008 AS PE for OCR Teacher Resource File 2nd Edition 3.I.10 3 The cardiovascular and respiratory systems Cardiovascular drift – answers 1. Cardiovascular drift is the gradual decrease in SV and increase in HR during prolonged exercise. 2. Arterial (systemic/pulmonary) pressure also declines. This effect is generally associated with an increase in body temperature, which causes an increase in Q redirected to the skin to reduce body temperature and a decrease in blood plasma volume as a result of sweating. Together, these decrease VR, which in turn decreases EDV, which in turn decreases SV. The HR increases to compensate for the decrease in SV to maintain the required Q. Relate the control mechanisms to HR response e.g. anticipatory rise due to effect of adrenaline on SA node. © Pearson Education Ltd 2008 89 3 The cardiovascular and respiratory systems 3.I.11 AS PE for OCR Teacher Resource File 2nd Edition Control of heart rate – answers 1. Put the following words into the appropriate space within the following section. involuntary medulla oblongata intrinsic cardiac neural motor timings sympathetic number The medulla oblongata in the brain This contains the following three control centres: • the cardiac control centre • the respiratory control centre • the vasomotor control centre. The cardiac control centre This controls the timings/number of heart contractions (HR), which are altered by three factors: • neural control (most important) • hormonal control • intrinsic control. The autonomic nervous system This is: 90 • under involuntary control • made up of sensory/receptor and motor nerves • motor nerves are referred to as the sympathetic and parasympathetic nerves. © Pearson Education Ltd 2008 AS PE for OCR Teacher Resource File 2nd Edition 3 The cardiovascular and respiratory systems Summary of factors affecting cardiac control centre – answers 3.I.12 Fill in the boxes to complete the summary. During exercise Neural Chemoreceptors In muscles, aorta & carotid arteries 1. Decrease in pH 2. Increase in pp CO2 3. Decrease in pp O2 Neural Baroreceptors In aorta & carotid arteries Increase in blood pressure = decrease in HR but neutralised due to demand Intrinsic for O2 Venous return Increase in VR (Starling’s Law) = increase in HR & SV Key + increases HR Key – decreases HR © Pearson Education Ltd 2008 Neural – + Cardiac control centre in medulla oblongata + Intrinsic + Hormonal + Proprioreceptors e.g. Golgi tendon organs, muscle spindles/joint receptors Increase in motor activity = increase in HR & SV Temperature Increase in temperature = increase in HR Adrenaline From adrenal glands Stimulates SA node directly via blood = increases in HR & SV 91