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Chapter 14 Test Review – Human Genetics – Test Thursday March 24, 2011
1. What is the difference between phenotype and genotype?
2. How is a recessive allele abbreviated?
3. Which type of inheritance patterns do the ABO blood genes demonstrate?
4. What are the three alleles responsible for ABO genes?
5. Are antigens and antibodies carbohydrates, proteins or lipids?
6. Concerning blood, where are antigens located?
7. Where are antibodies located?
8. In blood, what happens if antibodies attack antigens?
9. Which antigens are present in type A blood? B? O? AB?
10. Which antibodies are present in type A blood? B? O? AB?
11. What are the genotypes for type A blood? B? O? AB?
12. What is Rh factor?
13. What is agglutination? Why is it bad?
14. What do you need to perform blood typing?
15. What blood type could the children of a woman with type A blood and a man with type B blood
have? How about children of a woman with type A and man with type O?
16. If child 1 is type A+, child is type O-, mom is A+, dad is B-, what are the genotypes of the mom
and dad? What is the genotype of child 1?
Given the following results of blood tests conducted for patients at a hospital:
Patients
1
2
3
Anti – A Antibodies
+
+
-
Anti – B Antibodies
+
+
Anti – Rh Antibodies
+
+
( + means agglutination and - means no agglutination)
17. What is the blood type of patient 2?
18. Patient 1 was in an accident and needs a transfusion. Which blood type(s) would be compatible
donors?
19. If T=tongue roller and t=non-roller, match genotypes with correct phenotype.
20. If two parents show a dominant phenotype and their offspring show a recessive phenotype, what
must be true of the parents?
21. What are the possible gametes for a person with genotype AaCc?
22. In humans, cleft chin is dominant to no cleft. What is the genotype of someone with no cleft?
23. Do you always no the genotype of a person with a cleft chin?
Consider the genotypes Aa, AA, aa, Bb, BB, bb:
24. Which are heterozygous?
25. Which are homozygous dominant?
26. Which will have the same phenotype?
In humans, polydactyly (F) is dominant to 5 fingers (f).
27. If a person is polydactyl, what are their possible genotypes?
28. If a person heterozygous for polydactyly mates with a normal person, what are the
possible genotypes of its babies?
29. Jill and Jason are having their first child. What are the chances it will be a boy?
30. Which parent determines the child’s sex?
31. A trait is said to be sex linked when __________________?
32. What are some examples of sex-linked traits?
33. Why are sex linked disorders such as hemophilia more common in males than females?
34. How many X chromosomes do females have? Males?
35. What is the correct genotype of a male with hemophilia? A female with hemophilia?
36. When Thomas Morgan wanted to study human heredity, which species did he use to do
experiments on eye color?
37. How many pairs of chromosomes do humans have? How many are autosomes? How many sex
chromosomes? What are autosomes?
38. Jill and Jason have 3 daughters, and are expecting again. What is the chance that their next
child will be a girl?
39. What is the cause of chromosomal disorders? When does this happen?
40. What happens to the chromosome number of the gametes?
41. What is the genotype of a hemophilia carrier?
42. If this person has a child with a non-hemophiliac, what is the chance that the child will be a
normal son? What percent of their daughters will be normal (non-carriers). Could any of their sons
be carriers?
43. What are the inheritance patterns and symptoms of Sickle cell anemia, Cystic fibrosis, Huntington
disease, Down syndrome, color-blindness and hemophilia?
44. What does it mean to have multiple alleles?
45. How is a karyotype made?
46. What would you see on a normal human karyotype? How many of each? How are they
arranged? How is a karyotype annotated?
47. How does Down syndrome happen (most commonly)? Turner’s syndrome,? Kleinfelter’s?
Supermale?
48. What is the gender of the person whose
karyotype is shown to the left?
49. What is the disorder that this person has?
50. What is your evidence?
51. What are some of the characteristics of this
type of disorder?
52. What is a pedigree?
53. What is the inheritance pattern shown by this pedigree?
54. How do you know?
55. Using A,a, what is the genotype of person II4?
56. What is the genotype of person I3?
57. Make sure you remember how to do Punnett Squares for
sex-linked traits (like the Royal Blight activity) and for blood groups.