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NAT 5 Biology Multicellular Organisms Name: Class: Rosshall Academy Page 1 National 5 Biology Use the following table as a checklist for your revision. Remember to ask your teacher for help with anything you don’t understand. Learning Outcomes/ Mandatory Course Key Content Learned notes Completed questions 1. Specialised Cells Specialisation of cells, in animals and plants, leads to the formation of a variety of tissues and organs. Groups of organs which work together form systems. Stem cells in animals can divide and have the potential to become different types of cell. Stem cells are involved in growth and repair. Meristems are the sites of production of non-specialised cells in plants and are the sites for mitosis in a plant. These cells have the potential to become other types of plant cell and they contribute to plant growth. 2. Communication and Control Nervous control. Nervous system consists of central nervous system (CNS) and nerves. CNS consists of brain and spinal cord. Structure and function of brain to include cerebrum, cerebellum and medulla. Neurons are of three types, sensory, relay and motor. Receptors detect sensory input/stimuli. Electrical impulses carry messages along neurons. A synapse occurs between neurons. Chemicals transfer these messages across synapses. Structure and function of reflex arc. Hormonal control. Endocrine glands release hormones into the blood stream. Hormones are chemical messengers. Target tissues have cells with receptor proteins for hormones, so only some tissues are affected by specific hormones. Blood glucose regulation including the role of insulin, glucagon, glycogen, pancreas and liver. 3. Reproduction and Inheritance The structure of gametes and the sites of their production in plants and animals. Cells are diploid, except gametes, which are haploid. Fertilisation is the fusion of the nuclei of the two haploid gametes to produce a diploid zygote Comparison of discrete and continuous variation. Most features of an individual phenotype are polygenic and show continuous variation. Rosshall Academy Page 2 National 5 Biology Got help from my teacher Genetic terms, including gene, allele, phenotype, genotype, dominant, recessive, homozygous, heterozygous and P, F1 and F2. Carry out monohybrid crosses from parents through to F2. Reasons why predicted ratios are not always achieved. 4. World of Plants Leaf structure to include upper epidermis, palisade mesophyll, spongy mesophyll, vein, lower epidermis, guard cells and stomata. Other parts of the plant involved in water transport including root hairs and xylem vessels. Water minerals are transported in xylem vessels. Xylem vessels are dead and contain lignin for support. Water is required for transporting materials and for photosynthesis. The process of transpiration. Sugar is transported up and down the plant in living phloem. Structure of phloem tissue. 5. Health and Physiology Animal transport and exchange systems In mammals, nutrients, oxygen and carbon dioxide are transported in the blood. Pathway of oxygenated and deoxygenated blood through heart, lungs and body. Heart structure to include right and left atria and ventricles and location and function of valves. Blood vessels to include aorta, vena cava, pulmonary arteries and veins, coronary arteries and their function. Arteries have thick, muscular walls, a narrow central channel and carry blood under high pressure away from the heart. Veins carry blood under low pressure; have thinner walls and a wide channel. Veins contain valves to prevent backflow of blood and carry blood towards the heart. Capillaries form networks at organs and tissues, and are thin walled and have a large surface area, allowing exchange of materials. Red blood cells are specialised by being biconcave in shape, having no nucleus and containing haemoglobin. This allows them to transport oxygen efficiently in the form of oxyhaemoglobin. Rings of cartilage keep main airways open. Oxygen and carbon dioxide are exchanged through the alveolar walls. Alveoli have a large surface area, thin walls and a good blood supply for more efficient diffusion of gases. Mucus traps dirt and microorganisms and cilia moves this up and out of the lungs. Food is moved through the digestive system by peristalsis. Villi in the small intestine have a large surface area, thin walls and a good blood supply to aid absorption of glucose and amino acids. The lacteals absorb fatty acids and glycerol (the products of fat digestion). Effects of lifestyle choices on human transport and exchange systems Rosshall Academy Page 3 National 5 Biology 1. Specialised Cells Cells, Tissues and Organs Unicellular organisms are living things which consist of only one cell. To ensure the survival of the organism this one cell must carry out all the necessary functions and processes in order to sustain life. Multicellular organisms are highly developed organisms which consist of many (possibly millions) of cells. These cells are responsible for the continuation of life and will have a specific cell structure suited to their function. Cells like this are known as specialised cells. A group of specialised cells which carry out the same function are known as tissue (e.g. smooth muscle is composed of smooth muscle cells). Different tissue joined together to form a structural and functional unit is known as an organ (e.g. the stomach which is composed of different types of tissue including smooth muscle tissue and nerve tissue). Section of smooth muscle tissue. Animal Tissue Cell Type Specialised Structural Features Function Nerve Motor neurone Axon (long insulated extension of cytoplasm) Transmission of nerve impulses Blood Red blood cell Small, biconcave shape presents a large surface area. Rich supply of haemoglobin present Uptake and transport of oxygen to living cells. White blood cell Able to change shape; sacs of microbe-digesting enzymes present in some types Destruction of invading pathogens. Plant Tissue Phloem Root Cell Type Specialised Structural Features Function Sieve Tube Sieve plates and continuous system of cytoplasmic strands Transport of glucose and soluble carbohydrates Companion Cell Large nucleus in relation to cell size Controls sieve tube Epidermal cell Box-like shape allowing cells to fit together like a brick wall Protection Root Hair Long extension presenting large surface area in contact with soil solution Absorption of water and mineral salts. Rosshall Academy Page 4 National 5 Biology Animal Cells Motor neurone Red blood cells and white blood cells Plant Cells Phloem containing companion cells and sieve tubes Epidermal cell Root section composed of epidermal cells and root hairs Rosshall Academy Page 5 National 5 Biology Stem Cells Stem cells are undifferentiated cells (general cells) that have the potential to become any type of cell in animals. In humans there are two types of stem cell; embryonic stem cells and adult stem cells. Embryonic Stem Cells Embryonic stem cells account for all of the cells present in an embryo before development begins. They have the ability to differentiate into many of the cell types which make up the fully developed organism. Adult Stem Cells Adult stem cells occur in most of the organs in the body. They can be used in growth and repair of tissue that may have dead or damaged cells. These stem cells are slightly more restricted in development compared to embryonic stem cells as they are limited to the types of tissue in which they are found. Stem Cell Research In medicine there is potential use for stem cells including repairing damaged organs. This is a highly controversial topic as it can require the extraction of stem cells from embryos that are not implanted during IVF treatment or are still in the early stages of development. In this case the embryo can still develop normally after having cells removed. It is hoped that in the future stem cell research will be able to replace or repair organs of people who suffer from various illnesses including diabetes and Parkinson’s disease. Rosshall Academy Page 6 National 5 Biology Meristems Unlike in animals where stem cells are found throughout the body, undifferentiated cells in plants are restricted to areas called meristems. These are the only sites of cell division in plants. There are two types of meristems present in plants; apical meristems and lateral meristems. Apical Meristems Primary growth occurs at the apical meristems. These meristems are found at the root tips and shoot tips of plants. Cells produced here allow the plants to grow in height and increase their root length. Once the cells have multiplied by the process of mitosis, they then undergo differentiation. Some cells, for example, develop into xylem vessels which transport water in the plant or phloem tissue which transports glucose. Rosshall Academy Page 7 National 5 Biology 2. Communication and Control The Nervous System The nervous system consists of the brain, spinal cord and nerves. The brain and spinal cord together make the central nervous system (CNS). The nerves (neurons) make up the peripheral nervous system. There is one set of nerves known as the sensory nerves that carry information from receptors at the body’s sense organs to the central nervous system. These receptors have received information from a stimulus (e.g. seeing a football coming towards you). Another set of nerves known as motor nerves carry impulses from the central nervous system to other parts of the body e.g. muscles. These parts of the body are known as effectors as they carry out a response (e.g. kicking the ball). Component Function System Brain Controls the body Coordinates nerve impulses Central Nervous System Spinal Cord Relays impulses between the nerves and the brain Controls reflexes Central Nervous System Nerves Rosshall Academy Carries impulses to and from the CNS Page 8 Peripheral Nervous System National 5 Biology Nerves Nerves (or neurones) make up the peripheral nervous system. They consist of a cell body attached to extending nerve fibres. The cell body contains the nucleus. A nerve impulse is carried towards the cell body along a dendrite and away from it on an axon fibre. Axon fibres can differ in length depending on the type of neurone. A tiny space called a synapse occurs between the axon of one neurone and the dendrites of another. When a nerve impulse reaches the nerve endings of an axon, a chemical is released which diffuses across the synapse and triggers an impulse at the dendrite of the next neurone. Rosshall Academy Page 9 National 5 Biology The Brain The brain is a complex organ consisting of several different regions. The cerebrum is the largest part of the brain and can be split into hemispheres. The cerebellum is found at the back of the brain and the medulla is found at the top of the brainstem. Structure Cerebrum Cerebellum Medulla Hypothalamus Rosshall Academy Function Page 10 Conscious thought Limb movement Personality etc. Controls balance Controls muscular coordination Breathing rate Heart rate Regulates water balance Regulates temperature National 5 Biology Reflex Action Internal communication is required for survival of a multicellular organism. Cells in multicellular organisms do not work independently. An example of this internal communication is the one which is involved in the reflex action. A reflex action is what results from the transmission of nerve impulses through a reflex arc. The reflex arc is an arrangement of nerve cells that allow the body to respond rapidly and automatically to harmful situation. This protects the body from damage. Since many reflex actions need to be performed quickly they do not involve the brain. Instead a sensory nerve sends the information to a relay nerve in the spinal cord. This then relays the information to a motor nerve which can bring about a fast muscle contraction or a slower response from a gland. Reflex Action limb withdrawal blinking release of adrenaline Rosshall Academy Stimulus Response Protective Function heat from a naked flame contraction of flexor muscle removal of limb to safety harmful object approaching eye contraction of eyelid muscle prevention of damage to eye stress e.g. physical threat or excitement increases heart rate and blood sugar level. Diverts blood to brain and muscles prepares body for rapid activity e.g. running from danger Page 11 National 5 Biology Ouch! Maintaining Homeostasis For the human body to function efficiently it must maintain its internal environment. The body has various actions it can carry out in response to internal and external changes to maintain stable body conditions. This maintenance of the internal environment is controlled by homeostasis. Despite extreme changes in the external environment, homeostasis works to ensure that the internal environment stays within certain tolerable limits. Rosshall Academy Page 12 National 5 Biology Hormonal Control Hormones are chemical messengers that are transported in the blood. They are secreted by endocrine glands in the body and affect different target organs. The body’s response to hormones is usually slower and longer lasting than its response to nerve impulses. Below are an example of some hormones. Blood Glucose Regulation The body requires glucose for energy. Cells use up glucose during the process of respiration. The body only obtains glucose from the digestion of food, meaning that it is only present in the blood when food is being eaten. It is important that the blood glucose concentration is controlled so that there is a constant supply of glucose for respiration. The pancreas monitors and controls the concentration of glucose in the blood. If blood sugar levels get too high (above a set point) then special receptor cells in the pancreas respond by producing the hormone insulin. Insulin is a hormone that is transported in the bloodstream and allows glucose to be taken up by body tissues. It also travels to the liver where it activates an enzyme. This enzyme catalyses a reaction that converts glucose to glycogen. Rosshall Academy Page 13 National 5 Biology Insulin Glucose Glycogen About one hundred grams of glucose are stored as glycogen in the liver. Glucose can be added to or removed from the liver depending on the blood sugar levels. When the blood sugar level is low (i.e. between meals or at night) different cells in the pancreas respond by releasing glucagon into the bloodstream. When this hormone reaches the liver it activates a different enzyme which catalyses the reaction that converts glycogen to glucose. Glucagon Glycogen Glucose This returns the blood sugar level back to normal. Some people suffer from the disease diabetes which is when their blood sugar levels are not monitored properly. Type 1 diabetes is when cells in the pancreas do not produce enough insulin. This means that the blood sugar level is extremely high and the cells cannot use glucose efficiently. Most of the glucose is expelled from the body in urine. Type 1 diabetes used to be fatal but can now be treated with insulin injections and a controlled diet. Type 2 diabetes is when a person becomes resistant to insulin. People who are obese or have a poor diet are at more risk of developing type 2 diabetes. This form of diabetes usually develops later in life and can be treated with regular exercise and a controlled diet. Rosshall Academy Page 14 National 5 Biology 3. Reproduction and Inheritance All animals and plants reproduce. If a species did not reproduce they would become extinct. Some plants and unicellular organisms (e.g. amoeba) reproduce by asexual reproduction. This is when an organism can reproduce on its own. In unicellular organisms this is done by cell division. Most animals reproduce by sexual reproduction. Amoeba Sex Cells (gametes) For sexual reproduction to occur an organism must produce gametes. Gametes are another name for sex cells. These gametes are produced in specialised organs. The male gamete is called sperm. Sperm are very small and do not contain a food store. They have a tail which they use to propel themselves towards the female gamete. The female gamete is known as an ovum (egg). The ovum is large as it contains a food store. The ovum cannot move by itself. For a new individual to be formed, sperm must first fuse with the ovum allowing the nuclei of the two cells to fuse. The single cell resulting from this fusion of the parental gametes is termed the zygote. Once this cell divides the newly formed cells are now known as the embryo. It is the random combination of the sex cells from each parent that produces variety in offspring. This explains why children born to the same parents do not look identical to each other. Rosshall Academy Page 15 National 5 Biology Fertilisation in Animals The number of chromosomes in a cell of a living organism are known as the chromosome complement. The chromosome complement can vary depending on the species. Human body cells contain 46 chromosomes. These chromosomes can be arranged into 23 pairs. When a cell has a double set of chromosomes which can be arranged into pairs they are known as diploid cells. Human body cells are diploid cells. Gametes only have a single set of chromosomes that cannot be arranged into pairs. These are known as haploid cells. The fusing of two gametes ensures that the offspring produced contains the correct number of chromosomes (46 chromosomes). Rosshall Academy Page 16 National 5 Biology Gamete Production Sperm are produced in the testes of the male. Once the sperm has been produced, muscles around the testes force the sperm into the sperm duct and then into the urethra where they and then are expelled from the penis. Bladder Bladder Ova are produced in the ovaries of a female. The ovum enters the oviduct which transports the ovum towards the uterus. If sperm is expelled from the penis into the vagina then the sperm swim through the uterus into the oviduct where fertilisation occurs. Only one sperm can fertilise an ovum. The fertilised egg (zygote) is then transported through the oviduct into the uterus where the embryo develops. Rosshall Academy Page 17 National 5 Biology Fertilisation in Plants Structure of a Flower Sexual reproduction (requiring the fusion of two gametes) occurs in plants as well as animals. The flower contains the reproductive organs of a plant. The flowers of many different plants are built to the same basic plan although they may not all be exactly alike. Rosshall Academy Page 18 National 5 Biology Structure Function Sepals To protect the flower when it is a bud Nectary Makes sugary nectar which insects eat Carpel Female part containing female gametes Ovary Produces ovules (female gametes) Stamen Male part containing male gametes Anther Produces pollen grains (male gamete) Stigma Catches pollen Petals Bright colours to attract insects. Pollination Pollen is made inside the anther. When they ripen the pollen is released. Pollen grains are like specks of dust. They contain the plant’s male sex cell. This has to reach the egg cell (ovule) in the ovary. Pollination is the transfer of pollen from the anther to the stigma. Variation The differences between members of the same species are called variation. A species is a group of organisms that can interbreed to produce fertile offspring. There are two types of variation, continuous and discrete. Discrete Variation If the variation in a population allows individuals to be divided into two or more distinct groups, the characteristic shows discrete variation. Examples of discrete variation are: Ear Lobe Attachment Tongue Rolling Ability Eye Colour Flower Colour Rosshall Academy Page 19 National 5 Biology Continuous Variation If the variation in a characteristic can be measured (e.g. height) and it shows a wide range occurring between two extremes (e.g. the shortest and the tallest), it is an example of continuous variation. In this case individuals cannot be easily divided into distinct groups. Examples of continuous variation are: Height Pulse Rate Hand Span Seed Mass Inherited Characteristics Inherited characteristics are determined by genetic information received from the parents. Some examples of inherited characteristics and their possible phenotypes are shown in the table below: Organism Inherited Characteristics Possible Phenotypes Human hair colour black, brown, red, blonde tongue-rolling ability roller, non-roller height tall, dwarf seed shape smooth, wrinkled wing shape straight, curved eye colour red, white Pea Plant Fruit Fly Rosshall Academy Page 20 National 5 Biology The development of these inherited characteristics are controlled by genes. Genes are the small units that make up chromosomes. Genes are arranged along the chromosomes like a string of beads. Gene At least two forms of a particular gene exist, e.g. tongue roller or non-tongue roller, attached or unattached earlobe. The different forms of a gene are called alleles. Some characteristics are controlled by the allele of a single gene. An example of this is the ability to roll the tongue. Other characteristics are controlled by alleles of many genes. An example of this is height which varies from one extreme (very tall) to another extreme (very small). This is known as polygenic inheritance. Many features of a person’s appearance are polygenic and show continuous variation. Genotype and Phenotype The outward appearance of a characteristic in an organism is its phenotype. The complete set of genes an organism possesses is its genotype. We have all started life as a zygote with 46 chromosomes – 23 from the father, 23 from the mother. This explains why we have some characteristics from both parents. At fertilisation each chromosome from the sperm pairs up with the matching chromosome from the egg. This brings together the two sets of genes in the chromosomes together. The genes for hair colour pair up, the genes for nose shape pair up etc. The genes in the pair may be identical. For example, both genes might produce a tongue roller, but if one gene is for tongue rolling and the other gene is for non-tongue rolling the genes are now in competition. In this example the person will be a tongue roller because the gene for tongue rolling is more powerful than the gene for non-tongue rolling. Genes which dominate other genes are called dominant genes. Genes which are dominated by other genes are called recessive genes. When a dominant gene pairs up with a recessive gene the dominant one produces the final phenotype. Rosshall Academy Page 21 National 5 Biology An organism with two identical genes for a characteristic is said to be homozygous (you may also see the terms pure-breeding and true-breeding. These both mean homozygous). An organism with two different types of genes for a characteristic is said to be heterozygous. Monohybrid Crosses In diagrams genes are usually represented by letters. Capital letters are used for dominant genes. Lower case letters are used for recessive genes. Example T = gene for tongue rolling t = gene for non-tongue rolling Genotype = TT Genotype = tt Phenotype = tongue roller Phenotype = non-tongue roller Remember that when the gametes are produced they will have half the number of chromosomes and therefore half the number of genes. The sex cells will contain one allele from each gene pair, not two. For example the gamete produced from the tongue roller will contain the allele T and the gamete produced from the non-tongue roller would contain allele t. If these two gametes were to fuse then the offspring produced would have the genotype Tt and would be able to roll their tongue (as they contain at least one dominant gene). Rosshall Academy Page 22 National 5 Biology A cross such as this one can be described as a monohybrid cross because only one difference is being investigated (tongue rolling ability). In a monohybrid cross each original parent is true-breeding for the form of the inherited characteristic it possesses. Example P Generation X Phenotype – Blue Eyes Phenotype – Brown Eyes Genotype - bb Genotype - BB F₁ Generation Phenotype – Brown Eyes Genotype - Bb F₂ Generation B b B BB Bb b Bb bb 3:1 Ratio 3 Brown : 1 Blue Rosshall Academy Page 23 National 5 Biology Gregor Mendel (1822-84) was a monk who performed monohybrid crosses using pea plants. These pea plants demonstrated discrete variation. Mendel made important discoveries regarding inherited characteristics. Monohybrid crosses like this always produce a 3:1 ratio in the F₂ generation. This however rarely happens in nature because fertilisation is a random process. Rosshall Academy Page 24 National 5 Biology 4. The World of Plants The Need for a Transport System in Plants Plants need water for photosynthesis. Water enters the roots of the plant and must be transported upwards to the leaves where photosynthesis takes place. All living cells need a supply of glucose as well as water. The glucose made in the leaves by photosynthesis must be transported downwards to the parts of the plant that have no chlorophyll and cannot make their own food e.g. root cells. Water and minerals are transported upwards from the roots to the leaves in tubes called xylem vessels. Water is absorbed by root hairs from the soil by the process of osmosis. Xylem vessels are hollow tubes that carry water and minerals to all parts of the plant. Xylem vessels are strengthened by rings or spirals of tough, woody lignin. This lignin helps to support the plant. Xylem vessels are dead as they have no nucleus or cytoplasm. The food made by plants during photosynthesis is called glucose. Glucose is carried from the leaves to every part of the plant in tubes called phloem sieve tubes. Phloem contain two types of cells; sieve tubes and companion cells. All phloem cells are living. The end walls have pores and together these are called sieve plates. These allow glucose to be transported in the strands of cytoplasm from one cell to another. Rosshall Academy Page 25 National 5 Biology Transport tissues in Plants xylem Water is carried to the leaves from the roots in transport tissue called xylem phloem Food (glucose) is carried from the leaves to the roots and growing part of the plant in transport tissue called phloem Water can however be lost from a plant by the process of transpiration. Transpiration is when water inside the leaves of a plant evaporates and escapes through tiny holes on the underside of leaves called stomata. Factors such as light intensity, temperature, wind and humidity can affect the rate of transpiration. Factor Description Explanation Light Intensity In bright light transpiration increases Temperature Transpiration is faster in higher temperatures Transpiration is slower in humid conditions The stomata open wider to allow more carbon dioxide into the leaf for photosynthesis Evaporation and diffusion are faster at higher temperatures Diffusion of water vapour out of the leaf slows down if the leaf is already surrounded by moist air Water vapour is removed quickly by air movement, speeding up diffusion of more water vapour out of the leaf Humidity Wind Transpiration is faster in windy conditions Stomata are pores which allow for gas exchange by plants. They are open during daylight but closed in darkness. Guard cells are pairs of cells which surround each stoma and control when the stomata open and close. The sections of leaf closest to the stomata constantly have a low concentration of water as it is continually being lost to the environment. This creates a water concentration gradient. As water is lost through the stomata, more water is drawn out of the xylem vessels to replace what is lost. Water moves from the xylem into the leaf by osmosis. Some of this water is used by the spongy mesophyll, palisade mesophyll and guard cells for photosynthesis whilst some water is used to keep the plant cells turgid. Rosshall Academy Page 26 National 5 Biology Structure of a leaf Leaves generally have a large surface area to trap the light energy from the sun. They are also very thin to allow carbon dioxide to diffuse quickly into the leaf cells and allow the excess oxygen to diffuse out. The leaf is made of layers of cells, each with a different function to make photosynthesis an efficient process Structure Function Waxy cuticle Prevents evaporation of water vapour from the upper surface of the leaf Thin outer layer - has no chloroplasts so allows light to pass through to mesophyll cells Main site of photosynthesis. Cells contain many chloroplasts. Cells are arranged to allow maximum absorption of light energy Cells are loosely packed, with moist air spaces between them to allow gases to diffuse quickly into the cells Lower layer of cells containing many pores called stomata (singular, stoma) Cells that surround the stomata and control the opening and closing of the stomata. Stomata allow entry of carbon dioxide and the exit of excess oxygen and water vapour. Upper epidermis Palisade mesophyll Spongy mesophyll Lower epidermis Guard cells Rosshall Academy Page 27 National 5 Biology 5. Health and Physiology The Heart The heart is a muscular pump which pumps blood to all body cells and to the lungs. The heart has four chambers. The two upper chambers are called atria (singular: atrium) and the two lower changes are called ventricles. Note that the wall of the left ventricle is thicker than the wall of the right ventricle. This is because the left ventricle pumps blood all around the blood whereas the right ventricle only pumps blood to the lungs. Rosshall Academy Page 28 National 5 Biology Blood from all parts of the body enters the heart through two main veins called vena cava. This blood is deoxygenated and enters the right atrium of the heart. It then passes into the right ventricle. From the right ventricle the deoxygenated blood is pumped through the pulmonary arteries to the lungs. In the lungs, the blood loses carbon dioxide and gains oxygen by diffusion. The pulmonary veins return the oxygenated blood to the heart through the left atrium. From there the oxygenated blood is pushed into the left ventricle. The left ventricle pumps the oxygenated blood into the aorta and then onto all parts of the body. pulmonary artery pulmonary vein aorta vena cava Blood Vessels There are three types of blood vessel: arteries, veins and capillaries. Arteries Arteries carry blood away from the heart. Each time the heart beats blood is forced into the arteries at high pressure. Arteries have thick muscular walls to withstand this high pressure. Every time the heart beats, a spurt of blood passes along the arteries. This can be felt as a pulse. Apart from the pulmonary artery, all arteries carry oxygenated blood. Veins Veins carry blood towards the heart. By the time the blood starts moving back to the heart it is at low pressure. The inside of a vein is relatively wider than an artery allowing the blood to flow through it more easily. Veins also contain valves which prevent blood flowing backwards. Rosshall Academy Page 29 National 5 Biology Blood Capillaries Capillaries connect arteries to veins and allow exchange of materials between blood cells and cells of the body. They are microscopic and highly branched. The walls of the capillaries are only one cell thick. This allows exchange of material (e.g. glucose) to take place between the blood and surrounding cells. The aorta branches into other arteries which deliver oxygenated blood to the body tissues. As the heart is a working muscle it requires a constant supply of glucose and oxygen to keep it functioning. These substances are delivered to the cells of the heart tissue through the coronary artery. When the coronary artery gets blocked with plaque, it deprives the heart of oxygen. This can lead to health issues such as angina or more seriously cardiac arrest. These conditions can arise from a poor diet, lack of exercise or underlying health issues such as diabetes. Fatty deposits and blockages in blood vessels can lead to other health issues. Blood clots can occur in the blood vessels. Blood clots are vital when someone is injured as it prevents them from bleeding out. Blood clots in blood vessels however can deprive body tissues from oxygen. In the brain this can lead to a stroke. A stroke can lead to brain damage and can be fatal. A stroke can also be caused when a blood vessel ruptures at the brain. Some Rosshall Academy Page 30 National 5 Biology factors that increase the risk of blood clots are high fat or high salt diet, trauma and inherited disorders. Stress can also lead to health issues including blood clots. Blood In mammals nutrients, oxygen and waste products such as carbon dioxide are carried in the blood. The blood is composed of red blood cells, white blood cells, platelets and plasma. White blood cells are a part of the immune system and platelets are what help blood clot. Plasma is the watery fluid in which blood cells are carried. It also contains dissolved substances such as glucose and amino acids. A small volume of carbon dioxide is carried in the plasma but it is limited as it can make the blood acidic. The majority of the carbon dioxide enters the red blood cells to be transported. Rosshall Academy Page 31 National 5 Biology Red blood cells carry oxygen and some carbon dioxide. Red blood cells contain a pigment called haemoglobin which readily combines with oxygen when it is in high concentration. This occurs at the lungs. Oxygen is released in the capillaries around body tissues where the oxygen concentration is low. A lack of iron means that haemoglobin cannot be made. This can lead to anaemia which is when body tissues do not receive enough oxygen. Red blood cells are extremely numerous and have a biconcave shape which offers maximum surface area for oxygen uptake. Red blood cells are specialised to carry oxygen. Lungs Every person has two lungs located inside the chest. Inside each lung there is a series of branching tubes through which air passes. When you breathe in, air passes down the trachea (windpipe). The trachea is held open by rings of cartilage. The trachea then splits into two bronchi (single – bronchus), one leading to each lung. Each bronchus then splits to form many smaller branching tubes called bronchioles. The bronchioles end in tiny air sacs called alveoli. There are millions of alveoli in each lung. It is in the alveoli that gas exchange takes place. When we breathe in, oxygen from the air is absorbed into the blood and carbon dioxide from the blood is passed into the air. Rosshall Academy Page 32 National 5 Biology There are four main features of the alveoli that make them efficient at gas exchange: 1. There are many alveoli which creates a large surface area. 2. They have thin walls which allows for quick diffusion of gases. 3. They receive a good blood supply so that large volume of gases can be exchanged. 4. They have a moist inner lining which allows gases to dissolve before diffusing. The inside of the alveoli are lined with mucus. Mucus also lines the trachea. The function of mucus in the trachea is to catch dirt and microorganisms that may enter the body when a person inhales. Hair-like extensions called cilia line the trachea. They beat creating a wavelike motion that moves the mucus up out of the trachea and into the stomach where the microorganisms are destroyed by the stomach acid. Tobacco smoke contains harmful substances like tar and smoke which can damage the lungs. Tar coats the inside of the lungs and causes coughs. This can damage the alveoli which makes it difficult for gas exchange. Tar can cause cancer of the lungs, mouth and throat. Hot smoke can damaged the ciliated cells. This means that people have to cough to remove the mucus from their lungs. This can result in bronchitis. The Small Intestines The small intestines are part of the digestive system. The small intestine is designed to complete the digestive process and then absorb the soluble food products into the bloodstream. These include the products of fat, carbohydrate and protein digestion. Digestion is necessary to breakdown the large insoluble molecules into small soluble molecules so they can diffuse into the bloodstream. Food moves from the stomach into the small intestine. In the intestines food is moved by the process of peristalsis. Rosshall Academy Page 33 National 5 Biology Peristalsis is a wave of muscular contractions behind the ball of food (bolus) which pushes it along the length of the gut. This also happens in the oesophagus. The small intestine has the following features which make it efficient at absorbing soluble food products: 1. It is very long. 2. The inner surface is folded to increase the surface area for absorption. 3. It has very thin walls to allow for easy diffusion of the digested products. 4. It has a rich blood supply to absorb the digested food products and transport them elsewhere in the body. The inner surface of the small intestine is lined with finger-like extensions called villi. Inside each villus is a dense network of blood capillaries and a single lacteal. It is into these two kinds of vessel that the digested food products pass. The blood capillaries absorb: Simple sugars (products of carbohydrate digestion) Amino acids digestion) (products of protein The lacteal absorbs: Rosshall Academy Page 34 Fatty acids and glycerol (products of fat digestion) National 5 Biology