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Download Structure-Function studies of novel anticoagulants from snake venoms.
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NUS Graduate School for Integrative Sciences and Engineering Research Project Write-up Title of Project : Structure-Function studies of novel toxins from snake venoms Name of Supervisor : Prof. R. Manjunatha Kini Contact Details: Dept of Biological Sciences National University of Singapore 14 Science Drive 4 Singapore 117543 Tel: 65165235 Fax: 67792486 email: [email protected] We have been involved in isolation and characterization of novel toxins from snake venoms and identified a number of new toxins that belong to known family of toxins, but with different biological properties. We have also identified a few new families of snake venom toxins. The new toxins include (a) Ohanin (a protein toxin which crosses the blood-brain barrier and induces hypo locomotion in mice. (b) Acetylcholine receptor toxins including denmotoxin (c) Waprins is a new family of proteins with 50 amino acid residues and four disulfide bonds that we described recently. (d) New families of toxins which are yet to be named.
