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PENGANTAR EPIDMIOLOGI PENYKIT MENULAR 1 Epidemiologi Definisi Studi yg mempelajari distribusi dan determinant status atau kejadian yg berhubungan dengan kesehatan pada sekelompok populasi, dan aplikasi studi ini adalah untuk mengkontrol / mengendalikan masalah kesehatan Last ed. Dictionary of Epidemiology Epidemiologi Penyakitamenular Definisi : Epidemiologi penyakit menular terfokus dalam mempelajari distribusi dan determinan penyakit menular dalam populasi. Epidemiologi Penyakitamenular Klasifikasi Penyakit Berdasarkan etiologi (kausa) Penyakit infeksi Penyakit non infeksi Etiologi (organism) : Tuberkulosis, Campak, Malaria, dsb Manifestasi klinik : Meningitis, Encefalitis, Rinitis, Diare ??, dsb Epidemiologi Penyakitamenular Berdasarkan Durasi : Penyakit akut Penyakit kronik Peak symptoms within 3 months (acute) or longer than 3 months (chronic) Epidemiologi Penyakitamenular Acute infection vs. chronic infection Acute Infection An infection characterized by sudden onset, rapid progression, and often with severe symptoms Chronic Infection An infection characterized by delayed onset and slow progression Types of Diseases Acute Diseases MENULAR TIDAK MENULAR Examples Common cold, pneumonia, mumps, measles, pertussis, typhoid fever, cholera Appendicitis, poisoning, trauma Chronic Diseases MENULAR Tuberculosis, AIDS, Lyme disease, syphilis, rheumatic fever TIDAK MENULAR Diabetes, coronary heart disease, osteoarthritis, cirrhosis of the liver 5/25/2017 Definition of communicable diseases A communicable disease is an illness due to a specific infectious (biological) agent or its toxic products capable of being directly or indirectly transmitted: from man to man, from animal to man, from animal to animal, or from the environment (through air, water, food, etc..) to man. Definition of communicable diseases Epidemiology Communicable Disease A disease that can be transmitted from one individual to another Contagious Disease The study of the transmission of disease A communicable disease that is easily spread from one individual to another Noncommunicable Disease A disease that is not transmitted from one individual to another Definition of communicable diseases Communicable Diseases-biological agents Biological agents = microorganism - Virus - Fungus -Bacteria - Protozoa - Helminthes - Others form of microorganism Non Communicable Diseases-Non biological Agents - Physics - Nutrition - Chemical -etc Definition of disease & infectious disease Disease Any deviation from a condition of good health and well-being Infectious Disease A disease condition caused by the presence or growth of infectious microorganisms or parasites Etiologi Durasi Akut Kronis Infeksi Common cold Pneumonia Campak Gondongan Pertusis Typhoid Kolera Kusta TBC AIDS Demam rheumatik Hepatitis B Non Infeksi Keracunan (intoksikasi insektisida dan logam, dsb) Trauma Penyakit Jantung Koroner Diabetes Mellitus Kanker Stroke 12 Classification of Diseases & Health Problems Organ or Organ System – i.e., heart disease, kidney disease, respiratory infection Causative Agent – Biological Agents – Chemical Agents – Physical Agents Communicable vs Non communicable Acute vs Chronic –Peak symptoms within 3 months (acute) or longer than 3 months (chronic) Chap 4: Prevention and Control Causative Agents for Diseases & Injuries Biological Agents Viruses Rickettsiae Bacteria Fungi Protozoa Metazoa Chemical Agents Pesticides Food additives Pharmacologics Industrial chemicals Air pollutants Cigarette smoke Physical Agents Heat Light Radiation Noise Vibration Speeding objects DEFINITIONS INFECTION - The entry, development or multiplication of an infectious agent in the body tissues of man or animals INFECTIOUS DISEASE - A clinically manifest disease of man/animal resulting from an infection COMMUNICABLE DISEASE - An illness due to a specific infectious agent OR its toxic products that arises through transmission from a reservoir to a susceptible host either directly or indirectly Some communicable diseases may not be infectious BUT all infectious diseases are communicable. communicable but not infectious: -tetanus - botulism - staphylococcal food poisoning INCUBATION PERIOD - time interval between initial contact with an infectious agent and the first appearance of symptoms associated with the infection COMMUNICABLE PERIOD - time during an infectious agent may be transferred from an infected host/reservoir to another susceptible host Communicable Disease Model Model Communicable Disease Model Agent The element that must be present in order for the diseases to occur Communicable Disease Model Host Agent Any susceptible organism invaded by an infectious agent Communicable Disease Model Host Agent Environment All other factors that inhibit or promote disease transmission Chain of Infection A model to conceptualize the transmission of a communicable disease from its source to a susceptible host Chain of Infection Pathogen - The disease-causing agent Chain of Infection Pathogen Reservoir • The habitat in which an infectious agent normally lives and grows – Human: Anthroponoses, symptomatic or asymptomatic – Animal: Zoonoses – Environmental: Plants, soil, and water Chain of Infection Pathogen Reservoir Portal of exit • The path by which an agent leaves the source host Chain of Infection Pathogen Reservoir Portal of exit How pathogens Transare passed mission Modes of Transmission Direct: Immediate transfer - Direct contact - Droplet spread Indirect - Airborne - Vehicleborne - Vectorborne Modes of Transmission of the Agent to a New Host: A mode of transmission is essential for the infectious agent to bridge the gap between the portal of exit from the reservoir and the portal of entry of the host. Modes of transmission can be classified as direct or indirect. Routes of transmission Direct Indirect Skin-skin Herpes type 1 Mucous-mucous Food-borne STI Across placenta toxoplasmosis Through breast milk HIV Sneeze-cough Influenza Salmonella Water-borne Hepatitis A Vector-borne Malaria Air-borne Chickenpox Ting-borne Scarlatina Exposure A relevant contact – depends on the agent Skin, sexual intercourse, water contact, etc (www) Chain of Infection Pathogen Reservoir Portal of exit Portal Transmission of entry - Agent enters susceptible host Respiratory Oral Skin Intravenous Gastrointestinal Chain of Infection Pathogen Reservoir Portal of exit Portal Transmission of entry New host - Final link is a susceptible host Levels of Prevention • Primary Prevention – The forestalling of the onset of illness or injury during the pre-pathogenesis period (before the disease process begins) • Secondary Prevention – The early diagnosis and prompt treatment of diseases before the disease becomes advanced and disability becomes severe • Tertiary Prevention – The retraining, reeducation, and rehabilitation of the patient who has already incurred disability Pencegahan primer Adl Upaya pencegahan yg dilakukan saat proses penyakit belum mulai (pd periode pre-patogenesis) dengan tujuan agar tidak terjadi proses penyakit T.a: 1. Promosi kesehatan 2. Perlindungan khusus Riwayat Alamiah Penyakit 31 Pencegahan sekunder Adl Upaya pencegahan yg dilakukan saat proses penyakit sudah berlangsung namun belum timbul tanda/gejala sakit (patogenesis awal) dengan tujuan proses penyakit tidak berlanjut T.a: 1. Early diagnosis & prompt treatment Riwayat Alamiah Penyakit 32 2. Disability limitation Tingkat pencegahan tertier Bila telah terjadi defect /kerusakan struktural ataupun disabilitas: maka untuk mencegah semakin buruknya kondisi atau menetapnya disabilitas dilakukan usaha preventif tertier dengan rehabilitasi Riwayat Alamiah Penyakit 33 Prevention of Communicable Diseases • Pathogen – Pasteurization – Chlorination – Antibiotics – Antivirals – Disinfectants Prevention of Communicable Diseases • Human Reservoir – Isolation – Surveillance – Quarantine – Drug treatment Prevention of Communicable Diseases • Portal of Exit – Gowns – Masks – Condoms – Hair nets – Insect repellents Prevention of Communicable Diseases • Transmission – Isolation – Hand washing – Vector control – Sanitary engineering – Sneeze glass – Sexual abstinence – Safer sex Prevention of Communicable Diseases • Portal of Entry – Masks – Condoms – Safety glasses – Insect repellents Prevention of Communicable Diseases • Establishment of Disease in New Host – Immunizations – Health education – Nutrition promotion – Sexual abstinence Noncommunicable Disease Model Your genetic endowment Noncommunicable Disease Model Environment Your genetic endowment Behavioral choices Air Pollution Diseases of the Heart and Blood • Coronary heart disease (CHD): Characterized by damage to the coronary arteries. • Atherosclerosis: Narrowing of the blood vessels resulting from the build-up of fatty deposits on the walls of the blood vessel. • Cerebrovascular disease (stroke): Blood supply to the brain is disrupted. Cancer • Malignant neoplasm: Occurs when cells lose control over their growth and division. As these cells continue to grow they eventually develop a “new growth”—a tumor • Metastasis: Parts of the tumor break off and travel to the rest of the body’s organs and continue their growth. Other Top Noncommunicable Diseases 1. Chronic obstructive pulmonary disease 2. Diabetes mellitus 3. Chronic liver disease and cirrhosis Prevention of Noncommunicable Diseases • Primary Prevention – Adequate food intake – Good opportunities for education, employment, and housing – Efficient community services – Health promotion – Access to medical services – Protection from the environment – Protection from occupational hazards – Empowerment for one’s own health Prevention of Noncommunicable Diseases • Secondary Prevention – Mass screenings – Case-finding measures – Adequate health personnel, equipment, and facilities – Personal screening (self breast or testes exams) – Hemoccult tests – Pap tests Prevention of Noncommunicable Diseases • Tertiary Prevention – Adequate emergency medical personnel, services, and facilities – Understand unmodifiable risk factors – Significant behavioral or lifestyle changes (Modifiable risk factors) – Support groups – Counseling