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10: General Pharmacology Pharmacology Definitions (1 of 2) • Pharmacology – The science of drugs, including their ingredients, preparation, uses and actions on the body • Dose – Amount of medication given • Action – Therapeutic effects expected on the body Pharmacology Definitions (2 of 2) • Indications – Therapeutic uses for a particular drug • Contraindications – Conditions in which a medication should not be given • Side effects – Actions of a drug other than the desired ones Medication Names • Trade name – Brand name given by manufacturer • Generic name – Original chemical name • Prescription drugs – Given by pharmacists according to doctor’s order • Over-the-counter (OTC) drugs – Available without a prescription Routes of Administration (1 of 3) • Intravenous (IV) injection – Injected directly into the vein • Oral – Taken by mouth; enters body through digestive system • Sublingual – Placed under the tongue; absorbed by mucous membranes Routes of Administration (2 of 3) • Intramuscular (IM) injection – Injection into the muscle • Intraosseous (IO) – Injection into the bone marrow • Subcutaneous (SC) injection – Injection into tissue between skin and muscle Routes of Administration (3 of 3) • Transcutaneous – Medications absorbed through the skin • Inhalation – Medications inhaled into the lungs • Per rectum (PR) – Administration by rectum Dosage Forms (1 of 4) • Tablets – Materials mixed with medication and compressed under pressure • Capsules – Gelatin shells filled with powdered or liquid medication Dosage Forms (2 of 4) • Solutions – Liquid mixture of one or more substances • Suspensions – Mixture of fine particles distributed throughout a liquid by shaking Dosage Forms (3 of 4) • Metered-dose inhaler – Miniature spray canister, used to direct medication through the mouth into the lungs • Topical medications – Lotions, creams, and ointments applied to skin Dosage Forms (4 of 4) • Transcutaneous medications – Designed to be absorbed through the skin • Gels – Semi-liquid substances administered orally • Gases for inhalation – Oxygen Medications Carried on EMS Unit Oxygen • Required by all cells of the body • Administered as a gas for inhalation • Ignites easily, requiring caution near sources of ignition Activated Charcoal • Suspension used to absorb ingested poisons • Often combined with a laxative • Administered orally as a suspension Oral Glucose • Glucose is used by cells for energy. • Patients with low blood glucose are hypoglycemic. • It is administered orally as a gel. Aspirin • • • • Reduces pain Reduces fever Reduces inflammation Cardiac uses Assisted-Administration Medications Epinephrine • Increases heart rate and blood pressure and decreases muscle tone of bronchi • Eases breathing problems in asthma or allergic reactions • May be delivered by MDI, SC, or IM Administering Epinephrine by Injection • Sterilize skin. • Insert needle and draw plunger back. • Inject medication. • Dispose of needle. Metered-Dose Inhaler • Medication should be delivered as the patient is inhaling. • Device may include spacer. Nitroglycerin • Increases blood flow by relieving spasms and causing arteries to dilate • May decrease blood pressure • Available in tablet or spray General Steps to Administer Medications (1 of 2) • Obtain orders from medical control. • Verify proper medication and prescription. • Verify form, dose, and route of the medication. • Check expiration date and condition of the medication. General Steps to Administer Medications (2 of 2) • Reassess vital signs, especially heart rate and blood pressure, at least every 5 minutes or as the patient’s condition changes. • Document Patient Medications • Clue you in to patient conditions • Especially helpful when patient has altered mental status • Include over-the-counter medications and dietary supplements