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Dr Marcus Laux Clinical Professor QORE Competency METABOLIQ and QORE • METABOLIQ Infusions Reds & Greens • Macro meets Mighty Micro • Health Optimized for Life! • No Fluff…just good stuff with Science • No Regrets….only real Results ‘the proof of the pudding… … is in the eating’ “After hydrogen, the most common thing in the universe is stupidity.” - Albert Einstein Congrats, it only took 100 years! The first testicular guard, the "Cup," was used in hockey in 1874 and the first helmet was used in 1974. That means it took only 100 years for men to realize that their brain is also important. Nutritional Illiteracy and Misinformation U.S. has dropped to 49th place in overall life expectancy among the world’s nations. In 1999, the WHO ranked USA 24th. Super-Sized Ambulance • 1 in 10 Folks Worldwide are OBESE • Massively Morbidly Obese--the new norm! • Boston’s Emergency Medical Services has ambulance with a hydraulic lift for the heaviest patients. • EMS routinely transport folks at least 450 pounds. • EMS Capt. “…to be honest with you, with a 500, 600, 700 pound patient- its just too much for you! Pharmageddon "the prospect of a world in which medicines and medicine produce more illhealth than health, and when medical progress does more harm than good". Pharmageddon… A Pill for every ill? • Its everywhere today-work, school, in the car next to you, in the elevator, in your home! • 1 in 2 people are taking at least one Rx drug!!! • 136 drugs cause cognitive impairment • Polypharmacy- anti-cholinergic compounds • Histamine H2 receptor antagonists, cardiac medications; digoxin, betablockers; corticosteroids, non-steroidal anti-inflammatory and antibiotics can all cause acute and chronic confusion • Prescription Drugs Induce Violence FDA Adverse Event Reporting System- 31 Common Prescriptions linked to homicides! • Most dangerous- Antidepressants Pristiq (desvenlafaxine), Paxil (paroxetine) and Prozac (fluoxetine) (10.9X). • Top most dangerous drugs: Antidepressants; also Insomnia, an (ADHD)(10.3X), a Anti-malarial, and Smoking Cessation drug.(18X) • Acts of violence towards others are a genuine and serious adverse drug event associated with a relatively small group of drugs. So Young and Sooooo Many Pills!! • More than 25% of Kids and Teens in the U.S. take Prescriptions on a Regular Basis • Nearly 7% are on two or more drugs • Rx’s antihypertensives going 5.5 million –plus statins, anti-diabetic, sleep meds, etc • Asthma Rx ……….45,388,000 • ADHD Rx……….....24,357,000 • Antidepressant Rx…9,614,000 Lilly Stops Alzheimer’s Drug Trials • Eli Lilly & Co. halted two late-stage clinical trials with drug, Semagacestat. • Major setback on leading theory on Alzheimer's treatment, i.e. plaque reduction. ...showed worse cognitive functioning and less ability to perform daily living tasks on drug vs. placebo, plus higher risk for skin cancer! Brush your Pearly Whites Studies indicate that the more plaque on your teeth, the greater your risk for having a heart attack. Creating Life in the Lab – First Synthetic Cell J. Craig Venter co-mapped the human genome in 2001 He reconstructed the genome of a bacterium that successfully "booted up" (2010) NASA’s Fermi Space Telescope- study high-energy physics in remote universe Thunderstorms produce beams of ANTI-MATTER that rain into space Jan 2011 Sun & Earth’s Electromagnetic Fields What Say You? “Whether you believe you can do a thing or not, you are right.” - Henry Ford You Save Your Own Life Four Preventable Risk Factors Reduce Life Expectancy • 4.9 years in men • 4.1 years in women • Smoking, high blood pressure, elevated blood glucose and obesity responsible for killing for hundreds of thousands from chronic diseases; cardiovascular diseases, cancers and diabetes. Blueprint to Avoid the Blues • Hospital checklist cuts the risk of death nearly in half for patients who come in for surgery • Checklists could avert tens of thousands of surgical deaths and hundreds of thousands of serious complications annually in the US • Complications dropped by 31 percent per patient The New England Journal of Medicine. Published November 11, 2010 Structure is Key to QORE Anthocyanins • Flavonoid compounds from blueberries and strawberries may reduce blood pressure • regulate blood pressure via vascular blood flow, vascular reactivity, and glucose uptake • ***Endothelial NO regulation instead of general antioxidant effect American Journal of Clinical Nutrition 2011, Volume 93, Pages 338-347, "Habitual intake of flavonoid subclasses and incident hypertension in adults” Gynostemma blood sugar effects on DM 2 • Fasting plasma glucose significantly declined • Post-treatment fasting blood glucose levels were significantly lower • Levels of HbA1c decreased • Study suggests that the hypoglycemic mechanism may involve improvements in insulin resistance- not phanoside increasing insulin release….new finding! Antidiabetic effect of Gynostemma pentaphyllum tea in randomly assigned type 2 diabetic patients. Horm Metab GRb1 significantly increased neural stem cells GRb1 found in Panax quinquefolium & Gynostemma pentaphyllum • GRb1 significantly increased neural stem cells – AKA neural precursors cells • Induces Neurogenesis after brain ischemia new support-Neuroprotective • First time to show that GRb1 is capable of increasing Brain-Derived Neurotrophic Factor (BDNF) expression after stroke Journal of Ethnopharmacology Vol 132, Issue 2, Pages 393-39, doi:10.1016/j.jep.2010.07.033 “Ginsenoside Rb1 regulates the expressions of brainderived neurotrophic factor and caspase-3 and induces neurogenesis in rats with The pathogenic role of intestinal flora in IBD and colon cancer Current Drug Targets. 2008;9:395-403. Rescigno M. • Maintaining the right balance of beneficial bacteria in the gastrointestinal tract might help protect against conditions such as inflammatory bowel disease (IBD) and ultimately cancer (May 2008) • In research conducted, probiotics positively shifted the composition of bacteria in the gut, and reduced the development of tumors in animals Optimizing Thru Total Health The Absolute State of the Science The Apex in the Art of Human Care METABOLIQ Weight loss to Body-Wise QORE Nature makes you, Qivana makes YOU better! MAKE YOUR CHANGE TODAY!