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Chapter 14 The Respiratory System Week 4 Hs 130 Agenda     Questions from Last Week Review Chapter 14 Question and Answer Session Answer any Questions. Mosby items and derived items © 2008 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 2 STRUCTURAL PLAN   Basic plan of respiratory system would be similar to an inverted tree if it were hollow; leaves of the tree would be comparable to alveoli, with the microscopic sacs enclosed by networks of capillaries (Figure 14-1) Passive transport process of diffusion is responsible for the exchange of gases that occur during respiration. Mosby items and derived items © 2008 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 3 Mosby items and derived items © 2008 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 4 RESPIRATORY TRACTS  What comprises the:  Upper respiratory tract—  Lower respiratory tract— Mosby items and derived items © 2008 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 5 Answer-RESPIRATORY TRACTS   Upper respiratory tract—nose, pharynx, and larynx Lower respiratory tract—trachea, bronchial tree, and lungs Mosby items and derived items © 2008 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 6 RESPIRATORY MUCOSA     Specialized membrane that lines the air distribution tubes in the respiratory tree (Figure 14-2) More than 125 mL of mucus produced each day forms a “mucous blanket” over much of the respiratory mucosa Mucus serves as an air purification mechanism by trapping inspired irritants such as dust and pollen Cilia on mucosal cells beat in only one direction, moving mucus upward to pharynx for removal Mosby items and derived items © 2008 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 7 Mosby items and derived items © 2008 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 8 NOSE  Structure     Nasal septum separates interior of nose into two cavities Mucous membrane lines nose Frontal, maxillary, sphenoidal, and ethmoidal sinuses drain into nose (Figure 14-3) Functions-What are the Functions?   Warms and moistens inhaled air Contains sense organs of smell Mosby items and derived items © 2008 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 9 Answer-Nose Functions   Warms and moistens inhaled air Contains sense organs of smell Mosby items and derived items © 2008 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 10 Mosby items and derived items © 2008 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 11 PHARYNX  Structure (Figure 14-4)   Pharynx (throat) about 12.5 cm (5 inches) long Divided into nasopharynx, oropharynx, and laryngopharynx  Two nasal cavities, mouth, esophagus, larynx, and auditory tubes all have openings into pharynx  Pharyngeal tonsils and openings of auditory tubes open into nasopharynx; tonsils found in oropharynx  Mucous membrane lines pharynx  Functions-What is the function of the Pharynx? Mosby items and derived items © 2008 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 12 Answer-PHARYNX  Functions   Passageway for food and liquids Air distribution; passageway for air Mosby items and derived items © 2008 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 13 Mosby items and derived items © 2008 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 14 LARYNX  Structure (Figure 14-5)     Several pieces of cartilage form framework • Thyroid cartilage (Adam’s apple) is largest • Epiglottis partially covers opening into larynx Mucous lining Vocal cords stretch across interior of larynx Functions-What is the function? Mosby items and derived items © 2008 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 15 Function--LARYNX  Functions  Air distribution; passageway for air to move to and from lungs  Voice production Mosby items and derived items © 2008 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 16 Mosby items and derived items © 2008 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 17 Mosby items and derived items © 2008 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 18 TRACHEA  Structure (Figure 14-6)      Tube about 11 cm (4.5 inches) long that extends from larynx into the thoracic cavity Mucous lining C-shaped rings of cartilage hold trachea open Function—What is the function? Obstruction   Blockage of trachea occludes the airway, and if blockage is complete, causes death in minutes Tracheal obstruction causes more than 4000 deaths annually in the United States Mosby items and derived items © 2008 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 19 Answer--TRACHEA  Function—passageway for air to move to and from lungs Mosby items and derived items © 2008 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 20 Mosby items and derived items © 2008 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 21 BRONCHI, BRONCHIOLES, AND ALVEOLI  Structure     Trachea branches into right and left bronchi Each bronchus branches into smaller and smaller tubes eventually leading to bronchioles Bronchioles end in clusters of microscopic alveolar sacs, the walls of which are made up of alveoli (Figure 14-7) Function-What is the function? Mosby items and derived items © 2008 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 22 BRONCHI, BRONCHIOLES, AND ALVEOLI  Function   Bronchi and bronchioles—air distribution; passageway for air to move to and from alveoli Alveoli—exchange of gases between air and blood (Figure 14-8) Mosby items and derived items © 2008 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 23 Mosby items and derived items © 2008 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 24 LUNGS AND PLEURA  Structure (Figure 14-9)      Size—large enough to fill the chest cavity, except for middle space occupied by heart and large blood vessels Apex—narrow upper part of each lung, under collarbone Base—broad lower part of each lung; rests on diaphragm Pleura—moist, smooth, slippery membrane that lines chest cavity and covers outer surface of lungs; reduces friction between the lungs and chest wall during breathing (Figure 14-10) Function—breathing (pulmonary ventilation) Mosby items and derived items © 2008 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 25 Mosby items and derived items © 2008 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 26 RESPIRATION  Mechanics of breathing (Figure 14-11)  Pulmonary ventilation includes two phases called:  Changes in size and shape of thorax causes what?  Air pressure differences actually cause air to move into and out of the lungs Mosby items and derived items © 2008 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 27 Answer--RESPIRATION  Mechanics of breathing (Figure 14-11)  Pulmonary ventilation includes two phases called inspiration (movement of air into lungs) and expiration (movement of air out of lungs)  Changes in size and shape of thorax cause changes in air pressure within that cavity and in the lungs Mosby items and derived items © 2008 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 28 Mosby items and derived items © 2008 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 29 RESPIRATION  Inspiration   Active process—Define? Inspiratory muscles include: _______and _____________. Mosby items and derived items © 2008 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 30 Answer-RESPIRATION  Inspiration   Active process—air moves into lungs Inspiratory muscles include diaphragm and external intercostals • Diaphragm flattens during inspiration—increases topto-bottom length of thorax • External intercostals contraction elevates the ribs— increases the size of the thorax from the front to the back and from side to side  Increase in the size of the chest cavity reduces pressure within it; air then enters the lungs Mosby items and derived items © 2008 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 31 RESPIRATION  Expiration     Quiet expiration is ordinarily a passive process During expiration, thorax returns to its resting size and shape Elastic recoil of lung tissues aids in expiration Expiratory muscles used in forceful expiration are: ____________ and _____________ Mosby items and derived items © 2008 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 32 Answer-RESPIRATION  Expiration     Quiet expiration is ordinarily a passive process During expiration, thorax returns to its resting size and shape Elastic recoil of lung tissues aids in expiration Expiratory muscles used in forceful expiration are internal intercostals and abdominal muscles • Internal intercostals—contraction depresses the rib cage and decreases the size of the thorax from the front to back • Contraction of abdominal muscles elevates the diaphragm, thus decreasing size of the thoracic cavity from the top to bottom  Reduction in the size of the thoracic cavity increases its pressure and air leaves the lungs Mosby items and derived items © 2008 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 33 RESPIRATION  Exchange of gases in lungs (Figure 14-12)      Carbaminohemoglobin breaks down into carbon dioxide and hemoglobin Carbon dioxide moves out of lung capillary blood into alveolar air and out of body in expired air Oxygen moves from alveoli into lung capillaries Hemoglobin combines with oxygen, producing oxyhemoglobin Exchange of gases in tissues  Oxyhemoglobin breaks down into: __________and ________. Mosby items and derived items © 2008 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 34 RESPIRATION  Exchange of gases in lungs (Figure 14-12)      Carbaminohemoglobin breaks down into carbon dioxide and hemoglobin Carbon dioxide moves out of lung capillary blood into alveolar air and out of body in expired air Oxygen moves from alveoli into lung capillaries Hemoglobin combines with oxygen, producing oxyhemoglobin Exchange of gases in tissues  Oxyhemoglobin breaks down into oxygen and hemoglobin  Oxygen moves out of tissue capillary blood into tissue cells  Carbon dioxide moves from tissue cells into tissue capillary blood  Hemoglobin combines with carbon dioxide, forming carbaminohemoglobin Mosby items and derived items © 2008 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 35 BLOOD TRANSPORTATION OF GASES   Transport of oxygen Transport of carbon dioxide         Volumes of air exchanged in pulmonary ventilation (Figure 14-13) Volumes of air exchanged in breathing can be measured with a spirometer Tidal volume (TV)—amount normally breathed in or out with each breath Vital capacity (VC)—greatest amount of air that one can breathe out in one expiration Expiratory reserve volume (ERV)—amount of air that can be forcibly exhaled after expiring the tidal volume Inspiratory reserve volume (IRV)—amount of air that can be forcibly inhaled after a normal inspiration Residual volume (RV)—air that remains in the lungs after the most forceful expiration Rate—usually about 12 to 18 breaths a minute; much faster during exercise Mosby items and derived items © 2008 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 36 Mosby items and derived items © 2008 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 37 REGULATION OF RESPIRATION (Figure 14-14)  Regulation of respiration permits the body to adjust to varying demands for oxygen supply and carbon dioxide removal  Most important central regulatory centers in medulla are called respiratory control centers (inspiratory and expiratory centers)  Under resting conditions, nervous activity in the respiratory control centers produces a normal rate and depth of respirations (12 to 18 per minute)  Respiratory control centers in the medulla are influenced by “inputs” from receptors located in other body areas:  Cerebral cortex—voluntary (but limited) control of respiratory activity  Receptors that influence respiration • Chemoreceptors respond to changes in carbon dioxide, oxygen, and blood acid levels—located in carotid and aortic bodies • Pulmonary stretch receptors—respond to the stretch in lungs, thus protecting respiratory organs from overinflation Mosby items and derived items © 2008 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 38 Mosby items and derived items © 2008 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 39 TYPES OF BREATHING       Eupnea— Hyperventilation— Hypoventilation— Dyspnea— Apnea— Respiratory arrest— Mosby items and derived items © 2008 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 40 TYPES OF BREATHING Describe the following:       Eupnea—normal breathing Hyperventilation—rapid and deep respirations Hypoventilation—slow and shallow respirations Dyspnea—labored or difficult respirations Apnea—stopped respiration Respiratory arrest—failure to resume breathing after a period of apnea Mosby items and derived items © 2008 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 41 Question and answers      1. The upper respiratory tract includes all of the following except the: a. nose b. trachea c. pharynx d. larynx Mosby items and derived items © 2008 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 42  ANS: B-Trachea Mosby items and derived items © 2008 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 43      The mucous blanket: a. only covers the nose and throat b. traps dust, pollen, and other contaminants c.only covers the alveoli and bronchioles d. both B and C above Mosby items and derived items © 2008 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 44  ANS:  B traps dust, pollen, and other contaminants Mosby items and derived items © 2008 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 45      All of the following are paranasal sinuses except the: a. frontal sinus b. maxillary sinus c. sphenoid sinus d. mandibular sinus Mosby items and derived items © 2008 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 46  ANS:  D mandibular sinus Mosby items and derived items © 2008 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 47      The function of the epiglottis is to: a. anchor the vocal cords b. change the pitch of the voice c. keep food from entering the trachea d. both A and B above Mosby items and derived items © 2008 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 48  ANS:  C keep food from entering the trachea Mosby items and derived items © 2008 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 49      The smallest of the air distribution tubes in the respiratory tract are the: a. secondary bronchi b. bronchioles c. alveolar ducts d. tracheae Mosby items and derived items © 2008 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 50  ANS:  C alveolar ducts Mosby items and derived items © 2008 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 51      Dyspnea is labored breathing that is often associated with: a. hypoventilation b. hyperventilation c. eupnea d. apnea Mosby items and derived items © 2008 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 52  ANS:  A hypoventilation Mosby items and derived items © 2008 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 53      Which term refers to a normal respiratory rate? a. dyspnea b. apnea c. eupnea d. hyperventilation Mosby items and derived items © 2008 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 54  ANS:  C eupnea Mosby items and derived items © 2008 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 55 True/Fals  The organs of the respiratory system are designed to perform two basic functions: air distribution and gas exchange. Mosby items and derived items © 2008 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 56  True Mosby items and derived items © 2008 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 57  The respiratory membrane lines most of the air distribution tubes in the respiratory system. Mosby items and derived items © 2008 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 58  False Mosby items and derived items © 2008 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 59  The nicotine in cigarette smoke stimulates the cilia to beat rapidly in both directions, stopping the efficient removal of the trapped debris. Mosby items and derived items © 2008 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 60  False Mosby items and derived items © 2008 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 61  The four paranasal sinuses are named for the bones in which they are found. They are the frontal, parietal, sphenoidal, and ethmoidal. Mosby items and derived items © 2008 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 62  ANS: F Mosby items and derived items © 2008 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 63  The tonsils are located in the pharynx. Mosby items and derived items © 2008 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 64  True Mosby items and derived items © 2008 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 65  In some lung diseases, the lungs lose their elasticity and their ability to recoil. This would have the greatest impact expiration. Mosby items and derived items © 2008 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 66  True Mosby items and derived items © 2008 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 67  In order for external respiration to take place, the alveoli must have a higher oxygen concentration and a lower carbon dioxide concentration than the blood in the lung capillaries.  Mosby items and derived items © 2008 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 68  True Mosby items and derived items © 2008 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 69  The cerebral cortex is responsible for the voluntary increase or decrease in breathing rate. Mosby items and derived items © 2008 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 70  True Mosby items and derived items © 2008 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 71 Any Questions Mosby items and derived items © 2008 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 72