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Questions 14 - 17 Energy Expenditure Themes 14. BMR • 9 187 4 Which statement regarding Basal Metabolic Rate (BMR) is CORRECT? A. Whole body BMR is generally lower in people who weigh more goes up with weight yes, 60% of daily EE B. BMR contributes more to whole body energy expenditure than diet induced thermogenesis 9 8 C. BMR is assessed by comparing food intake to weight gain no, calorimetry D. BMR is inversely proportional to lean body mass directly! E. Thyroid hormone lowers BMR they increase BMR! 15. Fuel Stores • Which statement is CORRECT? A. Brain can use fatty acids 1 8 7 35 171 big NO!!! B. Fatty acids can be converted into glucose big NO!!! C. Muscle glycogen is the major carbohydrate reserve for the brainalthough lots of glycogen in muscle, can’t access D. The total amount of glycogen stored in muscle is less than the total amount stored in liver no 250g vs 100g E. There is no specific protein that represents a store of amino acids a true negative statement!! 16. Measuring Metabolic Rate • 105 26 33 33 18 Both indirect calorimetry and the doubly-labeled water (D2O18) methods can be used to assess whole body energy expenditure. Which statement is CORRECT? A. Only indirect calorimetry can give an indication of which fuels are being burnt yes. RQ carbs is 1, fat is 0.7 B. The doubly-labeled water method measures oxygen production no, carbon dioxide C. The doubly labeled water method can be done over a shorter time frame than indirect calorimetry no, much longer D. Only the doubly labeled water method can be used to determine basal metabolic rate no, multicomponent E. Indirect calorimetry only works if the subject has consumed carbohydrates, not fat. a silly statement! 17. Leptin • 7 6 8 190 9 Which of the following statements regarding leptin is CORRECT? A. Leptin is secreted by the β-cells of the pancreas in response to a carbohydrate meal no, by WAT B. Obese subjects have a lower blood leptin concentration than non-obese subjects no, much higher C. Obese subjects are hyper-responsive to leptin no, resistant D. A lack of leptin will cause ravenous hunger absolutely E. In rodents, leptin inhibits thermogenesis in brown adipose tissue stimulates energy expenditure