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Anatomy of Skeletal System SKELETAL SYSTEM COMPOSED OF: -Bones -Cartilage -Joints -Ligaments Functions of Skeletal System SUPPORT: Hard framework that supports and anchors the soft organs of the body. PROTECTION: Surrounds organs such as the brain and spinal cord. MOVEMENT: Allows for muscle attachment therefore the bones are used as levers. STORAGE: Minerals and lipids are stored within bone material. BLOOD CELL FORMATION: The bone marrow is responsible for blood cell production. Bone Markings Bone Surface is not smooth, but shows: Bone markings which reveal where: -muscles, tendons, and ligaments attatched -nerves and blood vessels pass *bone marking may be: 1-projections or processes or 2-depressions or cavities Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Slide 5.9 Compact bone Structure Outer layer of bone, very hard and dense. Its structural unit is called Haversian systems or osteon. Matrix is composed of Ca salts (Ca carbonate and Ca phosphate) Osteocytes – living bone cells that live in matrix. Porous (Spongy) bone Sponge-like , located in the ends of long bones. Needle-like threads of bone that surround spaces.. These spaces are filled with red bone marrow which produces blood cells. Classification of Bones Long bones Typically longer than wide Have a shaft with heads at both ends Contain mostly compact bone • Examples: Femur, humerus Short bones Generally cube-shape Contain mostly spongy bone Examples: Carpals, tarsals Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Slide 5.4a Classification of Bones on the Basis of Shape Figure 5.1 Slide 5.4c Flat bones Thin and flattened Usually curved Thin layers of compact bone around a layer of spongy bone Examples: Skull, ribs, sternum Irregular bones Irregular shape Do not fit into other bone classification categories Example: Vertebrae and hip Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Slide 5.5a Gross Anatomy of a Long Bone Diaphysis Shaft,Composed of compact bone Epiphysis Ends of the long bone, composed mostly of spongy bone A plate of cartilage separates epiphyses from diaphysis for bone longitudinal growth. Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Figure 5.2a Slide 5.6 Periosteum Outside covering of the diaphysis Fibrous connective tissue membrane Sharpey’s fibers secure periosteum to underlying bone Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Figure 5.2c Slide 5.7 Structures of a Long Bone Articular cartilage Covers the external surface of the epiphyses (inside the joints ) Made of hyaline cartilage Decreases friction at joint surfaces Figure 5.2a Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Slide 5.8a Medullary cavity Cavity of the shaft Contains yellow marrow (mostly fat) in adults Contains red marrow (for blood cell formation) in infants Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Figure 5.2a Slide 5.8b Microscopic Anatomy of Bone Osteon (Haversian System) is the unit of bone structure which is composed of: Central (Haversian) canal Present in the center of an osteon Carries blood vessels and nerves Perforating (Volkman’s) canal Perpendicular to the central canal Carries blood vessels and nerves Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Slide 5.10a Microscopic Anatomy of Bone Figure 5.3 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Slide 5.10b Microscopic Anatomy of Bone( cont.) Lacunae Cavities containing bone cells (osteocytes) Arranged in concentric rings called Lamellae around the central canal Figure 5.3 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Slide 5.11a Microscopic Anatomy of Bone(cont.) Canaliculi Tiny canals Radiate from the central canal to lacunae to transport nutrients. Figure 5.3 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Slide 5.11b Between the ages of 16 and 25 years (influenced by estrogen or testosterone), all of the cartilage of the epiphyseal discs is replaced by bone. This is called closure of the epiphyseal discs (or we say the discs are closed) and a line appears instead seen in x-ray, and the bone lengthening process stops. NOTICE: - bones grow in width through periosteum. - bone change shape continuously by gravity &muscle pull. Slide 5.13a Long Bone Formation and Growth Figure 5.4a Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Slide 5.14a Long Bone Formation and Growth Figure 5.4b Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Slide 5.14b Homeostatic Imbalance Rickets is a disease of children in which the bones fail to calcify due to deficiency of calcium in the diet or vitamin D . As a result bone soften leading to bowing of legs and deformities of the pelvis, skull, and rib cage. Because the epiphyseal plates cannot be calcified, they continue to widen, and the ends of long bones become visibly enlarged and broad. Types of Bone Cells Osteocytes Mature bone cells present inside lacunae Osteoblasts Bone-forming cells Osteoclasts Break down bone matrix for remodeling and release of calcium. Bone remodeling is a process of balance between both osteoblasts and osteoclasts Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Slide 5.15 Fractures Closed fracture (simple): skin is intact Open fracture (compound): skin is open Fracture reduction : 1-closed reduction ,no surgery is needed 2-open reduction ,surgery is needed Repair of fracture Healing time for simple fracture is 6-8 weeks (longer in elderly people) .It occurs in FOUR major events 1-hematoma formation 2-fibrocartilage callus formation 3-bony callus formation 4-bone remodelling **Groth of long bones Long bones are first made of cartilage model , and ossification begins in the third month of gestation. Osteoblasts produce bone matrix in the center of the diaphyses (center of ossification)of the long bones and in the center of short, flat, and irregular bones. Bone matrix gradually replaces the original cartilage. The long bones also develop centers of ossification in their epiphyses. At birth, ossification is not yet complete and continues throughout childhood. Cartilage remains in isolated areas as bridge of the nose , parts of ribs and joints . Increase in bone length occurs in the epiphyseal discs(plates) at the junction of the diaphysis with each epiphysis. Bone grows in length as more cartilage is produced on the epiphysis side. On the diaphysis side, osteoblasts produce bone matrix to replace the cartilage. PARTS OF THE SKELETON 1- Axial skeleton - Skull and associated bones Auditory ossicles Hyoid bones - Vertebral column - Thoracic cage(Ribs+ sternum) 2- Appendicular skeleton -Pectoral girdle +upper limb -Pelvic girdle + lower limb The Axial Skeleton Skull and associated bones: Auditory ossicles Hyoid bone Vertebral column Thoracic cage Ribs + sternum The Skull and Associated Bones The Adult Skull •skull = 22 bones •cranium = 8 bones: frontal, occipital, 2 temporals, 2 parietals, sphenoid and ethmoid •facial bones = 14 bones: nasals, maxillae, zygomatics, mandible, lacrimals, palatines, inferior nasal conchae, vomer. •skull forms a larger cranial cavity -also forms the nasal cavity, the orbits, paranasal sinuses - mandible and auditory ossicles are the only movable skull bones •cranial bones also: attach to membranes called meninges -stabilize positions of the brain, blood vessels -outer surface provides large areas for muscle attachment that move the head or provide facial expressions Sutures All of the joints between cranial bones are immovable joints called sutures. It may seem strange to refer to a joint without movement, but the term joint (or articulation) is used for any junction of two bones. Four sutures are important: Coronal – between parietal and frontal Sagittal– between parietal bones Lambdoid – between the parietal and occipital Squamous – between the parietal and temporal. Figure 6.4 Sectional Anatomy of the Skull, Part I Frontal bone Forms the forehead Roof of the orbit articulates with parietal, sphenoid, lacrimal, nasal, ethmoid, zygomatic and maxilla superior and lateral to glabellar region – frontal sinuses inferior portion – supraorbital ridges with supraorbital notch (supraorbital nerve and artery) •Parietal bones -Part of the superior and lateral surfaces of the cranium -articulate with each other in sagittal suture -articulate with occipital, frontal, temporal and sphenoid bones •Temporal bone shows:mastoid process , styloid process,external acoustic meatus and temperomandibular joint . - Occipital bone Part of the base of the skull articulates with parietal, temporal and sphenoid Surrounds the foramen magnum projections = occipital condyles Sphenoid bone Contributes to floor of cranium The body of the bat has a depression called the sella turcica,which encloses the pituitary gland. Ethmoid bone Irregularly shaped bone Forms part of orbital wall Forms roof of nasal cavity two lateral masses – contain the ethmoid sinuses Two projections' called the superior and middle nasal conchae Cribiform plate: perforations for olfactory nerve, midline is the crista galli 14 Facial Bones Nasal (2) Mandible (1) Inferior nasal conchae (2) Maxillae (2) Lacrimal (2) Zygomatic (2) Palatine (2) Vomer (1) Bones of the Face Maxillae Paired bone Largest of facial bones Form upper jaw body contains the maxillary sinuses Zygomatic Bones Cheekbones Lateral wall of orbit Palatine bones Form posterior portion of hard palate Inferior nasal concha Located on each side of nasal septum Increase epithelial surface Create turbulence in inspired air Lacrimal Smallest bones bones in skull Forms nasolacrimal groove leading to nasolacrimal canal Delivers tears to nasal cavity Palatine & Vomer Vomer posterior part of nasal septum Forms inferior portion of nasal septum Articulates with maxillae and palatines Mandible lower jaw only freely movable bone of the skull moving articulations with temporal bone in temperomandibular joint. The Hyoid Bone Suspended by stylohyoid ligaments Consists of a body, greater horns and lesser horns. Base for muscles of the tongue and larynx Paranasal Sinuses Paired cavities in ethmoid, sphenoid, frontal and maxillary bones. Lined with mucous membranes and open into nasal cavity though openings called ostia Resonating chambers for voice, and lighten the skull. Sinusitis is inflammation of the sinuses leads to headache Infection can easily spread from the nose to the sinuses and from one sinus to the other as mucous membranes are continuous. Growth in human skull **The cranial and facial bones are first made of fibrous connective tissue. In the third month of fetal development, fibroblasts (spindle-shaped connective tissue cells) become more specialized and differentiate into osteoblasts, which produce bone matrix. From each center of ossification, bone growth radiates outward as calcium salts are deposited. This process is not complete at birth; a baby has areas of fibrous connective tissue remaining between the bones of the skull. These are called fontanels fontanels permit: - Compression of the baby’s head during birth without breaking the still thin cranial bones. - The growth of the brain after birth. Fontanels are “ soft spots,”. A baby’s skull is quite fragile and must be protected from trauma. By the age of 2 years, all the fontanels have become ossified, and the skull becomes a more effective protective covering for the brain. Homeostatic Imbalance Several congenital abnormalities may distort the skull. Most common is cleft palate, a condition in which the right and left halves of the palate fail to fuse medially (Figure 7.34). The persistent opening between the oral and nasal cavities interferes with sucking and can lead to aspiration (inhalation) of food into the lungs and aspiration pneumonia The Vertebral Column http://www.wisc-online.com/objects/index.asp?objID=AP12104 Adult Vertebral Column 26 vertebrae 24 individual vertebrae Sacrum Coccyx Seven cervical vertebrae Twelve thoracic vertebrae Five lumbar vertebrae Sacrum and coccyx are Fused together. Typical Vertebrae Body Vertebral arch weight bearing pedicles laminae Vertebral foramen Seven processes 2 transverse 1 spinous 4 articular The vertebrae are separated by discs of fibrous cartilage that act as cushions to absorb shock. An intervertebral disc has a tough outer covering and a soft center called the nucleus pulposus. Extreme pressure on a disc may rupture the outer layer and force the nucleus pulposus out.This is called DISC PROLAPSE . This may occur when a person lifts a heavy object improperly, that is, using the back rather than the legs and jerking upward, which puts sudden, intense pressure on the spine. Most often this affects discs in the lumbar region. Typical Cervical Vert. (C3-C7) Smaller bodies Larger spinal canal Transverse processes are shorter and has transverse foramen for vertebral artery Spinous processes of C2 to C6 often bifid 1st and 2nd cervical vertebrae are unique atlas & axis Atlas & Axis (C1-C2) The Atlas C1 is termed the atlas Lacks a body and spinous process Supports the skull Superior articular facets receive the occipital condyles Allows flexion and extension of neck Nodding the head “yes” The Atlas Figure 7.16a The Axis Has a body and spinous process Dens (odontoid process) projects superiorly Acts as a pivot for rotation of the atlas and skull Participates in rotating the head from side to side ,as if we refuse. The Axis Thoracic Vertebrae (T1-T12) All articulate with ribs Have heart-shaped bodies from the superior view Each side of the body bears demifacts for articulation with ribs Thoracic Vertebrae Spinous processes are long and point inferiorly Vertebral foramen are circular Transverse processes articulate with tubercles of ribs Allows rotation and prevents flexion and extension Lumbar Vertebrae Bodies are thick and strong Transverse processes are thin and tapered Spinous processes are thick, blunt, and point Vertebral foramina are triangular Allows flexion and extension – No rotation Sacrum (S1 – S5) Forms the posterior wall of pelvis Formed from 5 fused vertebrae Superior surface articulates with L5 Inferiorly articulates with coccyx Sacral promontory Where the first sacral vertebrae bulges into pelvic cavity Center of gravity is 1 cm posterior to sacral promontory Sacrum Sacral foramina Ventral foramina Passage for ventral rami of sacral spinal nerves Dorsal foramina Passage for dorsal rami of sacral spinal nerves Sacrum Figure 7.18a, b Coccyx Is the “tailbone” Formed from 3 – 5 fused vertebrae Offers only slight support to pelvic organs Bony Thorax Forms the framework of the chest Components of the bony thorax Thoracic vertebrae – posteriorly Ribs – laterally Sternum and costal cartilage – anteriorly Protects thoracic organs Supports shoulder girdle and upper limbs Provides attachment sites for muscles The Bony Thorax Figure 7.19a The Bony Thorax Figure 7.19b Sternum Formed from three parts : Manubrium – superior part Body – bulk of sternum Articulates with medial end of clavicles Sides are notched as articulations for costal cartilage of ribs . Xiphoid process – inferior end of sternum Ossifies around age 40 Sternum Anatomical landmarks Jugular notch Central indentation at superior border of the manubrium Sternal angle A horizontal ridge where the manubrium joins the body Ribs All ribs attach to vertebral column posteriorly True ribs - superior seven pairs of ribs Attach to sternum by costal cartilage False ribs – inferior five pairs of ribs ,attatch indirectly to the sternum floating ribs ribs 11–12 are short and free anteriuorly. Ribs Figure 7.20a Ribs Figure 7.20b Disorders of the Axial Skeleton Abnormal spinal curvatures Scoliosis – an abnormal lateral curvature Kyphosis – an exaggerated thoracic curvature Lordosis – an accentuated lumbar curvature – “swayback” Stenosis of the lumbar spine A narrowing of the vertebral canal The Appendicular Skeleton Allows us to move and manipulate objects Includes all bones other than axial skeleton, it includes: the limbs (upper & lower limbs) the supportive girdles (pectoral &pelvic girdles) th Figure 8–1 The Pectoral Girdle Also called the shoulder girdle Connects the arms to the body Positions the shoulders Provides a base for arm movement The Pectoral Girdle Figure 8–2a The Pectoral Girdle Consists of: 2 clavicles 2 scapulae Connects with the axial skeleton only at the manubrium(claviculosternal joint) The Clavicles Figure 8–2b, c The Clavicles Also called collarbones Long, S-shaped bones Originate at the manubrium (sternal end) Articulate with the scapulae (acromial end) The Scapulae Also called shoulder blades Broad, flat and triangular Articulate with arms and collarbone Anatomy of The scapula Figure 8–3a The Upper Limbs Arms, forearms, wrists, and hands Note: arm (brachium) = 1 bone, the humerus ANATOMY OF The Humerus Figure 8–4 The Humerus The bone of the arm Articulates with the glenoid cavity (fossa ) of the scapula above and with the trochlear notch of the ulna below The Forearm Figure 8–5 The Forearm Also called the antebrachium Consists ulna of 2 long bones: (medial) radius (lateral) Interosseous Membrane A fibrous sheet provides strength Connects lateral margin of ulnar shaft to radius The Wrist Figure 8–6 The Wrist 8 carpal bones: 4 proximal carpal bones 4 distal carpal bones allow wrist to bend and twist Homeostatic Imbalance The arrangement of carpal bones is concave anteriorly forming the carpal tunnel. Besides the median nerve (which supplies the lateral side of the hand), several long muscle tendons crowd into this tunnel. Overuse and inflammation of the tendons cause them to swell, compressing the median nerve, which causes tingling and numbness of the areas served. Pain is greatest at night. Those who repeatedly flex their wrists and fingers, such as those who work at computer keyboards all day, are particularly susceptible to this nerve impairment, called carpal tunnel syndrome. This condition is treated by splinting the wrist during sleep or by surgery Metacarpus (Palm) Five metacarpal bones radiate from the wrist to form the palm of the hand (meta = beyond). These are numbered 1 to 5 from thumb to little finger. The bases of the metacarpals articulate with the carpals proximally Their bulbous heads articulate with the proximal phalanges of the fingers. When you clench your fist, the heads of the metacarpals become prominent as your knuckles. Metacarpal 1, associated with the thumb, is the shortest and most mobile. It occupies a more anterior position than the other metacarpals. The joint between metacarpal 1 and carpals allows opposition, the action of touching your thumb to the tips of your other fingers. Phalanges (Fingers) The fingers, or digits of the upper limb, are numbered 1 to 5 beginning with the thumb, or pollex (pol′eks). In most people, the third finger is the longest. Each hand contains 14 miniature long bones called phalanges (fahlan′jēz). Except for the thumb, each finger has three phalanges: distal, middle, and proximal. The thumb has no middle phalanx. [Phalanx is the singular term for phalanges.] The Pelvic girdle Consists of 2 ossa coxae, the sacrum, and the coccyx It attaches the lower limbs to the axial skeleton, transmits the weight of the upper body to the lower limbs, and supports the visceral organs of the pelvis The OSSA COXAE Also called hipbones Strong to bear body weight &stress of movement Each is made up of 3 fused bones: ilium (articulates with sacrum) ischium pubis The Acetabulum (vinegar cup) called the hip socket Is the meeting point of the ilium, ischium, and pubis Articulates with head of the femur (Hip joint) Also landmarks of the Pubis Pubic symphysis: gap between pubic tubercles padded with fibrocartilage landmarks of the Ischium • Ischial tuberosity:posterior projection you sit on • Ischeal spine,superior to the tuberosity ,important during labour Divisions of the Pelvis Figure 8–9 Comparing the Male and Female Pelvis Female pelvis: The inlet is larger and more circular As a whole is shallower and bones are lighter and thinner Ilia flare more laterally Sacrum is shorter and less curved Ischial spines are shorter and farther apart ,thus the outlet is larger. Pupic arch is more rounded because the angle of the pupic arch is greater. Comparing the Male and Female Pelves Figure 8–10 The Lower Limbs Functions: weight motion bearing Bones of the Lower Limbs Femur (thigh) Patella (kneecap) Tibia and fibula (leg) Tarsals (ankle) Metatarsals (foot) Phalanges (toes) The Femur(longest, heaviest ) Figure 8–11 The Patella Also called the kneecap Formed within tendon of quadriceps femoris to decrease friction. The Tibia and Fibula Figure 8–13 The Tibia Also called the shinbone Supports body weight Larger than fibula Medial to fibula, form medial malleolus The Fibula • Attaches muscles of feet and toes • Smaller than tibia • Lateral to tibia, form lateral malleolus The Ankle Also called the tarsus: consists of 7 tarsal bones ,of them are: Talus, receives the end of tibia & Calcaneus (heel bone): transfers weight to ground attaches Achilles tendon Figure 8–14a Feet: Metatarsal Bones 5 long bones of foot Numbered 1-5, from medial to lateral Articulate with toes Phalanges: Hallux: bones of the toes big toe, 2 phalanges (distal &proximal) Other 4 toes: 3 phalanges (distal, middle & proximal phalanx) Shock absorption :occurs due to 1-Intervertebral discs 2- S-shaped vertebral column 3- Arches of the Foot Feet Arches Arches of the Foot :bones of the foot are arranged to form THREE strong arches, 2 longitudinal (medial & lateral)& 1 transverse Ligaments & tendons help to hold the bones firmly in the arched position but still allow a certain amount of sprigness Week arches are referred to as flat foot Figure 8–14b Articulations (Joints) Function Holds bones together Allows bones to move All bones articulate with at least one other bone except the hyoid. Classification of joints Functional classification: focuses on the amount of movement (synarthrosis, amphiarthrosis and diarthrosis) Structural classification : based on whether Fibrous, Cartilage or a joint cavity separates the bon ends at the joint. As a general rule, fibrous joints are immovable and synovial joints are freely movable . Types Synarthroses No movements Primarily in axial skeleton Bones connected with fibrous tissue ligament Examples : Skull sutures Types Amphiarthroses Slightly movable In axial skeleton Connected by cartilage Intervertebral joints, pubic symphysis Diarthroses – freely movable Also called synovial (fluid filled joint cavity) Primarily found in the limbs Plane of movement depends on the joint Synovial Joints have 4 features 1. Articular cartilage: hyaline 2. Joint Cavity: space filled with lubricating fluid 3.Fibrous Capsule: fibrous CT lined with a smooth synovial membrane 4. Reinforcing Ligament: can be inside or outside the joint capsule Synovial Fluid: viscous and lubricating Bursae: fluid filled sacs ,see later Tendons sheath an elongated bursa that rapes around a tendon subjected to friction. Types of synovial joints based on shape Plane(nonaxial) -Slipping or gliding movements -Intercarpel joints are best examples Hinge joints( uniaxial) Angular movement is allowed in only one plane like a hinge Examples :elbow,ankle and interphalangeal joints Ball-and-socket joints A spherical head of one bone fits into a round socket in another These Multiaxial joints allow movements in all axes including rotation Shoulder and Hip are examples Bursae Flattened fibrous sac lined with synovial membrane with thin synovial fluid Acts as bags of lubricant to reduce friction where ligaments, muscle, skin, tendon or bones rub together Disorders of joints Dislocation:Bone is forced out of its position. Reduction is done by experts only Bursitis: example falling on the knee Sprain: excessive stretch on a ligament Arthritis: inflammation of joints, may be -Acute: usually bacterial -Chronic: Rheumatoid ,Osteoarthritis and Gouty arthritis Developmental aspects Long bones are formed of Hyaline cartilage Flat bones of skull are formed of fibrous membranes At birth , some fontanels still remain By end of adolescence, the epiphyseal plates are fully ossified Adult skull is 1/8 & infant skull is 1/4 of the total body length At birth , cranium is huge relative to face , it is related to rapid growth of brain By 2 years skull is 3/4 adult size By 9 years , skull become nearly of adult size At birth, the spine is arched and convex posteriorly Secondary curvature which are convex anteriorly appear, with raising the head (cervical) & with start of walking(lumber) Primary curvatures still present in thorasic and sacral regions leading to S-shaped spine in adult At birth the UL(upper/lower) ratio is 1.7 to 1 At 10, UL is 1 to 1 Bones become stronger with pull of gravity &muscle contractions Osteoporosis, thin and fragile bones occurs in totally inactive persons. It occurs in half women after 65 and in20% of men after70(estrogen maintain healthy bones) Causes of Osteoporosis: - estrogen deficiency - diet poor in calcium & protein - lack of vitamin D - smoking - lack of exercise * pathologic fracture is the result END of Sk. system