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Introduction to the Human Body A. B. C. D. E. F. G. H. Anatomy and physiology defined Levels of structural organization Life processes Anatomical position Directional terms Planes and sections Body cavities Homeostasis 1. Body fluids and exchange 2. Regulation by nervous and endocrine mechanisms 3. Feedback systems Anatomy (Greek “anatome” =to cut up or dissect Physiology (Greek “physis” =nature Levels of Structural Organization Life Processes Metabolism= catabolism + anabolism Responsiveness Movement Growth Differentiation Reproduction Anatomical Position Directional Terms Superior vs. Inferior Anterior vs. Posterior Medial vs. Lateral Proximal vs. Distal Superficial vs. Deep superior Proximal Medial Lateral Distal inferior Anterior Posterior Planes and Sections 1.Sagittal a. midsagittal b. parasagittal 2. Frontal (coronal) 3.Transverse (cross) 4.Oblique Planes of the Body Sections Through the Body Body Cavities Body Cavities (also material In Atlas A (A. 12-A.22) and Handout 1-Body Regions 1. Dorsal a. cranial b. vertebral (spinal 2. Ventral a. thoracic (1) pleural-2 (2) mediastinum (a) anterior (b)middle(pericardial) (c) posterior b. abdominopelvic Homeostasis (Greek “homoi” =same “stasis” =standing still) Body Fluids and Exchange 1. Extracellular fluid (ECF) a. interstitial fluid b. plasma 2. Intracellular fluid The homeostatic responses of the body are regulated by the combined effects of the nervous system and the endocrine system. REGULATION OF HOMEOSTASIS Nervous system = electrical messages control events on a millisecond basis; short-term and very specific effects Endocrine system = chemical messages control events on a minute, hour, daily, monthly, etc. basis; longer-term and more widespread effects Operation of a Feedback System Condition Receptor Control Center Effectors Response Condition- A stimulus or stress disrupts homeostasis in a controlled condition which is monitored by a receptor. Receptor- responds to specific changes in the controlled condition and sends input to control center. Control Center- Receives input from receptors, integrates the information and provides output to specific effectors. Effectors-respond to output from the control center by bringing about some type of change in the body that counteracts the disruption in homeostasis. Response-the activity of the effectors brings the controlled condition back into normal homeostasis and the negative feedback system is shut down. Feedback System: Main Players WHAT IS A FEEDBACK SYSTEM? CONTROLLED CONDITION some physiologic state RETURN TO HOMEOSTASIS RECEPTOR senses a change in the condition EFFECTORS structure that restores homeostasis CONTROL CENTER integrates incoming information WHAT IS A NEGATIVE FEEDBACK SYSTEM? A feedback loop in which the body senses a change and activates mechanisms that reverse the change RETURN TO HOMEOSTASIS CONTROLLED CONDITION blood pressure decreased blood pressure rises turns off increased heart rate and vasoconstriction RECEPTOR baroreceptors in blood vessels decreased activity CONTROL CENTER EFFECTORS heart and arterial smooth muscle nervous output medulla of brain end Positive Feedback WHAT IS A POSITIVE FEEDBACK SYSTEM? A feedback loop in which the response reinforces the stimulus, triggering a cycle of ever-increasing response CONTROLLED CONDITION level of uterine stretch reinforcing effects RETURN TO HOMEOSTASIS labor forces baby’s head further into cervix increased RECEPTOR EFFECTORS stretch receptors in cervix uterine smooth muscle contraction increased activity CONTROL CENTER hypothalamic neurons of brain oxytocin secretion