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The Integumentary System A. Skin 1. Anatomy 2. Physiology 3. Epidermis 4. Dermis B. Glands 1. Sebaceous (oil) glands 2. Sudoriferous (sweat) glands a. Eccrine b. Apocrine C. Thermoregulation: homeostasis of body temperature Cells Tissues Organs System Integumentary System- Skin, hair, nails, glands, and enamel of teeth Integumentary System 1. epidermis 2. dermis 3. derivatives _______________ 4. hypodermis Skin Has 7 Functions 1. 2. 3. 4. 5. 6. 7. regulation of body temperature protection sensation excretion immunity blood reservoir synthesis of vitamin D Epidermis 1. keratinized stratified squamous epithelium 2. four main cell types: a. keratinocytes (90%) b. melanocytes (about 8%) c. Langerhans cells (1%) d. Merkel cells (1%) Epidermal Layers 1. stratum basale 2. stratum spinosum 3. stratum granulosum 4. stratum lucidum 5. stratum corneum ___________________ keratinizing system Thick Skin Keratinizing System Keratin gives skin a waterproof, anti-microbial, and abrasion-resistant barrier 25-30 rows of fat dead cells filled with keratin Thick skin only 3-5 rows of clear, dead cells packed With eleidin-keratin intermediate 3-5 rows-begin producing keratohyalin 8-10 rows-derived from Keratinocytes below- receive Melanin. Mitotic zone-keratinocyte stem Cells, melanocytes and Merkel cells. EPIDERMAL LAYERS (the keratinizing system) thick skin exfoliation cell death keratin eleidin keratinization stratum corneum stratum lucidum stratum granulosum keratohyalin stratum spinosum mitosis stratum basale dermis The House Dust MiteDermatophagoides Dermis 1. papillary 2. reticular ____________ functions Loose areolar tissue Elasticity, Extensibility, And Thermoregulation Dense irregular Skin Glands Axillary region, pubic, breasts, Beards in men. Viscous milky Fluid-no odor 1. Sebaceous (oil) glands 2. Sudoriferous (sweat) glands a. merocrine (eccrine) b. apocrine (eccrine) Sebum Secretion Combines with Sweat forms Acid mantle Most Common 90% water Thermoregulation Protective Functions of the Epidermis 1. 2. 3. 4. acid mantle role of keratin role of the stratum corneum role of the stratum granulosum Thermoregulation 1. homeotherms vs poikilotherms 2. arterio-venous (AV) plexuses AV plexus BODY TEMPERATURE CONTROL CONTROLLED CONDITION A stimulus or stress disrupts homeostasis by causing an increase in body temperature negative feedback RETURN TO HOMEOSTASIS Evaporation of sweat from skin removes body heat, thus lowering body temperature and mechanism turns off RECEPTOR Thermoreceptors in skin and hypothalamus are activated and send nerve impulses to the control center EFFECTORS 1. Increased sweat output 2. blood vessels vasodilate, bringing heat to body surface CONTROL CENTER Hypothalamic control center sends nerve impulses to sweat glands and skin blood vessels end