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Essentials of Human Diseases
and Conditions
4th edition
Margaret Schell Frazier
Jeanette Wist Drzymkowski
Chapter 6
Diseases and Conditions of the
Integumentary System
Learning Objectives
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Explain the functions of the skin.
Recognize common skin lesions.
Describe how seborrheic dermatitis affects
the skin.
Discuss the common causes of contact
dermatitis, atopic dermatitis, and psoriasis.
Elsevier items and derived items © 2009 by Saunders, an imprint of Elsevier Inc.
Learning Objectives (cont’d.)
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Describe the treatment of acne vulgaris.
Explain the pathologic course of herpes zoster.
Name the etiology of impetigo.
Explain why the treatment of cellulitis is important.
Cite examples of classifications of fungal infections of the skin.
Elsevier items and derived items © 2009 by Saunders, an imprint of Elsevier Inc.
Learning Objectives (cont’d.)
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List preventative measures for decubitis
ulcers.
Name the two most common parasitic insects
to infest man.
Describe how infestation can occur.
Name two common premalignant tumors.
Differentiate the three types of skin cancer.
Elsevier items and derived items © 2009 by Saunders, an imprint of Elsevier Inc.
Learning Objectives (cont’d.)
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Describe the guidelines for avoiding excessive sun exposure.
List some conditions that are caused by the abnormal
development or distribution of melanocytes.
Name some possible causes of alopecia.
State the cause of warts.
List some of the likely causes of deformed or discolored nails.
Elsevier items and derived items © 2009 by Saunders, an imprint of Elsevier Inc.
Chapter 6
Lesson 6.1
Components of the Integumentary
System
Skin and accessory organs:
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Hair
Nails
Glands
Skin layers
Dermis
Epidermis
Subcutaneous layer
Elsevier items and derived items © 2009 by Saunders, an imprint of Elsevier Inc.
Normal Skin
Elsevier items and derived items © 2009 by Saunders, an imprint of Elsevier Inc.
Common Skin Condition Symptoms
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cutaneous lesions or eruptions
pruritis (itching)
pain
edema (swelling)
erythema (redness)
inflammation
Elsevier items and derived items © 2009 by Saunders, an imprint of Elsevier Inc.
A Few Common Skin Lesions
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macule
plaque
cyst
pustule
scale
burrow
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papule
nodule
vesicle
crust
fissure
comedo
Elsevier items and derived items © 2009 by Saunders, an imprint of Elsevier Inc.
Skin Lesions
Elsevier items and derived items © 2009 by Saunders, an imprint of Elsevier Inc.
Skin Lesion (cont’d.)
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Note the differences between a macule and a
papule:
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Macule: small, flat, circumscribed lesion of
different color than the rest of the skin
Papule: a small firm, elevated lesion
Elsevier items and derived items © 2009 by Saunders, an imprint of Elsevier Inc.
Skin Lesion (cont’d.)
Elsevier items and derived items © 2009 by Saunders, an imprint of Elsevier Inc.
Skin Lesion (cont’d.)
Elsevier items and derived items © 2009 by Saunders, an imprint of Elsevier Inc.
Common Diseases of the Skin
Dermatitis
 Seborrheic dermatitis
 Contact dermatitis
 Atopic dermatitis (eczema)
 Psoriasis
Elsevier items and derived items © 2009 by Saunders, an imprint of Elsevier Inc.
Common Diseases of the Skin (cont’d.)
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Note the differences between seborrheic
dermatitis and contact dermatitis:
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seborrheic dermatitis – idiopathic condition
resulting in overproduction of sebum
contact dermatitis – localized redness and
swelling caused by an irritant or allergen
Elsevier items and derived items © 2009 by Saunders, an imprint of Elsevier Inc.
Common Diseases of the Skin
(cont’d.)
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Acne vulgaris: an inflammatory disease of
the sebaceous glands and hair follicles
Herpes zoster (shingles): an acute
inflammatory dermatomal eruption of painful
vesicles
Elsevier items and derived items © 2009 by Saunders, an imprint of Elsevier Inc.
Common Diseases of the Skin (cont’d.)
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Chickenpox is a precursor to shingles.
Both are caused by the herpes varicellazoster virus.
Elsevier items and derived items © 2009 by Saunders, an imprint of Elsevier Inc.
Chapter 6
Lesson 6.2
Common Diseases of the Skin (cont’d.)
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Impetigo: contagious, superficial skin
infection
Cellulitis: acute, diffuse, bacterial infection of
the skin and subcutaneous tissue
Elsevier items and derived items © 2009 by Saunders, an imprint of Elsevier Inc.
Dermatophytoses
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Tinea capitis
Tinea corporis (ringworm)
Tinea unguium
Tinea pedis (athlete’s foot)
Tinea cruris (jock itch)
Elsevier items and derived items © 2009 by Saunders, an imprint of Elsevier Inc.
Chapter 6
Lesson 6.3
Other Diseases of the Skin
Decubitis ulcers (bed sores): localized areas
of dead skin
Scabies: infestation by parasitic insects called
itch mites
Pediculus: infestation by lice; wingless
parasites that feed on human blood
Elsevier items and derived items © 2009 by Saunders, an imprint of Elsevier Inc.
Other Diseases of the Skin (cont’d.)
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Species that infest the head and body
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Pediculus humanus capitis – lice that infest the
head
Pediculus humanus corporis – lice that infest the
body
Phthirus pubis – pubic lice (crabs)
Sarcoptes scabiei – itch mites
Elsevier items and derived items © 2009 by Saunders, an imprint of Elsevier Inc.
Benign Tumors
Seborrheic keratosis: benign growths
originating in the epidermis
Dermatofibroma: benign, asymptomatic
growths that can be found anywhere on the
body
Achrochordon (skin tag): common benign
skin growths found mainly on the axilla, neck,
and inguinal areas of the body
Elsevier items and derived items © 2009 by Saunders, an imprint of Elsevier Inc.
Premalignant Tumors
Actinic keratosis: common pre-malignant
lesions found on sun-exposed areas of the
body
 Indications: an area of rough, vascular skin,
which later forms a yellow crust.
Elsevier items and derived items © 2009 by Saunders, an imprint of Elsevier Inc.
Skin Carcinomas
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Non-melanoma skin cancers
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Basal cell carcinoma (BCC)
Squamous cell carcinoma (SCC)
Malignant melanomas
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The ABCs of malignant melanoma:
• A = asymmetry
• B = border
• C = color
• D = diameter
Elsevier items and derived items © 2009 by Saunders, an imprint of Elsevier Inc.
Protection of Skin from the Sun
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Avoid exposure 10 a.m.– 3 p.m.
Plan outdoor activities for early morning or
late afternoon
Wear protective clothing
Use sunscreen
Elsevier items and derived items © 2009 by Saunders, an imprint of Elsevier Inc.
Abnormal Skin Pigmentation
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albinism: inability to produce melanin (inherited)
vitiligo: pale, irregular patches (may be an immune
system disorder)
melasma (chloasma): patches of darker skin on the
face
hemangiomas: benign lesions of highly vascularized
skin; they may be flat (port-wine stains), elevated, or
protuberant
Elsevier items and derived items © 2009 by Saunders, an imprint of Elsevier Inc.
Abnormal Skin Pigmentation (cont’d.)
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nevi (moles): small, dark collections of melanocytes
pityriasis: fungal infection; causes patches of flaky, light, or
dark skin on the trunk
abnormal suntan: unusual darkening of the skin resulting from
properly used medications
Elsevier items and derived items © 2009 by Saunders, an imprint of Elsevier Inc.
Chapter 6
Lesson 6.4
Causes of Alopecia (Baldness)
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heredity
aging process
systemic illness
dermatitis
Elsevier items and derived items © 2009 by Saunders, an imprint of Elsevier Inc.
More Common Diseases of the Skin
Verrucae (warts): warts are elevated growths
of the epidermis that result from hyperplasia
Deformed or discolored nails: any unusual
thickening, color variation, or change in
shape of fingernails or toenails
Elsevier items and derived items © 2009 by Saunders, an imprint of Elsevier Inc.