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Chapter 12 Integration of Nervous System Functions Presynaptic terminals associated with a postsynaptic neuron Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Sensation (Perception) • The conscious awareness of stimuli received by sensory receptors • Sensation requires – A stimulus – A receptor – Conduction of an action potential to the CNS – Translation of the action potential – Processing of the action potential in the CNS so that the person is aware of the sensation Sensory Areas of the Cerebral Cortex • Sensory pathways project to primary sensory areas in the cerebral cortex – Somatic sensory – Visual – Auditory – Taste – Olfactory Fig. 12.6 Sensory Areas of the Cerebral Cortex • organized topographically in somatic sensory cortex • post-central gyrus • Nerve distibutions – Size of body part = relative amt of sensory receptors there • More in face Fig. 12.7 Control of Skeletal Muscles • Lower motor neurons – Axons leave CNS thru nerves, innervate skeletal muscles (motor units) – Cell bodies found in cranial nuclei or anterior horn of spinal cord gray matter • Upper motor neurons – form tracts that directly or indirectly control the activities of lower motor neurons – Cell bodies in cerebral cortex, brainstem, and cerebellum Motor Area of the Cerebral Cortex • primary motor cortex is pre-central gyrus • organized topographically • premotor and prefrontal areas are staging areas for motor function Fig. 12.8 PAIN • sensation characterized by group of unpleasant and complex perceptual and emotional experiences • Triggers autonomic, psychological, somatic motor responses Two types of pain sensation 1. sharp, localized • rapidly conducted APs carried by large (diameter) myelinated axons 2. diffuse, burning/aching pain • APs from slower, smaller, less myelinated axons Analgesics • Pain relievers (reversible) • Block transmission of pain in spinal cord or • Cerebral cortex—modify pain reception Anesthetics • Depress nerve cell function; loss of sensation/concsciousness (reversible) • “Local”: injection; blocks APs • “general”: drugs act on reticular formation, lose consciousness Referred Pain • Pain sensation in a different part of body (not stimulus source) • Ex: in skin when internal organ is inflamed – Skin and organ neurons converge onto same ascending neurons in spinal cord – Brain can’t differentiate – Sensation referred to most superficial • Heart attacks...feel pain in left shoulder... Phantom Pain • Amputees • AP along pathway, integration sends pain sensation to sensory receptors • EVEN IF NO LONGER PRESENT IN THE BODY... • Another weird thing...hit your funny bone (ulnar nerve) & 4th/5th digits hurt Chronic Pain • Tissue damage (arthritis) or unknown cause • Varied levels of pain perception • Brain can regulate and suppress it • If that is non-functional, pain’s a problem & can be more intense • Chronic Pain Syndrome Just FYI…Memory • At least three kinds of memory exist – Sensory • Very brief (less than a second) retention of sensory input received by the brain while something is scanned, evaluated, and acted on – Short-term memory • Lasts for a few seconds to a few minutes and is limited to 7 or 8 pieces of information – Long-term memory • Lasts for hours or longer (a lifetime) • Two types – Explicit memory: retention of facts, such as names, dates, and places – Implicit memory: development of skills such as riding a bicycle or playing a piano Fig. 12.16 Effects of Aging on the Nervous System • There is general decline in sensory and motor functions as a person ages • Short-term memory is decreased in most older people • Thinking ability does not decrease in most older people Page 362