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Chapter 24 1 – The Digestive System The Digestive System • Gastroenterology: the science that deals with the structure, function, diagnosis, and treatment of diseases of the stomach and intestines. The Digestive System • The digestive system is the body system that is involved in the breakdown of food into useable nutrients and wastes. The Digestive System • Two groups of organs compose the digestive system: 1. The gastrointestinal (GI) tract 2. The accessory digestive organs The Digestive System • Organs of the GI tract include: I. Mouth II. Pharynx (throat) III. Esophagus The Digestive System • Organs of the GI tract cont’: IV. Stomach V. Small intestine VI. Large intestine The Digestive System • Accessory digestive organs include: I. Teeth II. Tounge III. Salivary glands The Digestive System • Accessory digestive organs cont’: IV. Liver V. Gall bladder VI. Pancreas The Digestive System • The digestive system performs six basic processes: 1. Ingestion 2. Secretion 3. Mixing & propulsion The Digestive System • Basic processes of digestion cont’: 4. Digestion 5. Absorption 6. Defecation The Digestive System 1. Ingestion is the process that involves taking foods and liquids into the mouth. The Digestive System 2. Secretion is the release, by cells within the walls of the GI tract and accessory organs, of water, acid, buffers, and enzymes into the lumen of the tract. The Digestive System 3. Mixing & Propulsion is the result of the alternating contraction and relaxation of the smooth muscles within the walls of the GI tract. The Digestive System 4. Digestion is the mechanical and chemical processes that break down food into small molecules. The Digestive System • Mechanical digestion involves the teeth cutting and grinding of food before it is swallowed and the smooth muscles of the stomach and the small intestine churning food. The Digestive System • Chemical digestion involves a series of catabolic reactions that break down large carbohydrate, lipid, and protein food molecules into smaller molecules that are usable by body cells. The Digestive System 5. Absorption is the passage of end products of digestion from the GI tract into blood or lymph for distribution to cells. The Digestive System 6. Defecation is the is emptying of the rectum, eliminating indigestible substances from the GI tract. Chapter 24 2 – Layers of the GI Tract GI Tract Layers • The four layers of the GI tract from deep to superficial are: 1. The mucosa 2. The submucosa 3. The muscularis 4. The serosa GI Tract Layers 1. The mucosa is the inner lining of the GI tract; it is a mucous membrane that is composed of a layer of epithelium, a layer of connective tissue and a thin layer of smooth muscle. GI Tract Layers 2. The submucosa is one of two middle linings of the GI tract, it consists of aerolar connective tissue. GI Tract Layers – The submucosa is highly vascular, it contains glands, lymphatic tissue and an extensive network of submocosal plexus. GI Tract Layers 3. The muscularis is the other middle lining of the GI tract, it consists of smooth muscle that is generally found in two sheets. GI Tract Layers – Between the smooth muscle layers of the muscularis is a second plexus of neurons – the myenteric plexus. GI Tract Layers 4. The serosa is the outer lining of the GI tract, it is a serous membrane composed of areolar connective tissue and mesothelium. Chapter 24 3 – Neural Innervation of the GI Tract Neural Innervation • The gastrointestinal tract is regulated by an intrinsic set of nerves known as the ‘enteric nervous system’ and by an extrinsic set of nerves that are part of the autonomic nervous system. Neural Innervation • The neurons of the ENS are arranged into two groups of plexuses: 1. The myenteric plexus 2. The submucosal plexus Neural Innervation 1. The myenteric plexus supply the smooth muscle layers of the muscularis and controls the frequency and strength of contractions of the muscularis. Neural Innervation 2. The submucosal plexus supply the secretory cells of the mucosal epithelium, controlling secretions of the organs of the GI tract. Homework • Finish handout: – “The Digestive System” • Study for mini-quiz