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4 Types of Tissues     Epithelial  Covers body surfaces and lines hollow organs, body cavities, duct, and forms glands Connective  Protects, supports, and binds organs.  Stores energy as fat, provides immunity Muscular  Generates the physical force needed to make body structures move and generate body heat Nervous  Detect changes in body and responds by generating nerve impulses Development of Tissues  Tissues of the body develop from three primary germ layers:  Ectoderm, Endoderm, and Mesoderm  Epithelial tissues develop from all three germ layers  All connective tissue and most muscle tissues drive from mesoderm  Nervous tissue develops from ectoderm  Internal organs develop from endoderm Tight Junctions  Web-like strands of transmembrane proteins   Fuse cells together Seal off passageways between adjacent cells   Common in epithelial tissues of the stomach, intestines, and urinary bladder Help to retard the passage of substances between cells and leaking into the blood or surrounding tissues Desmosomes  Contain plaque and cadherins that extends into the intercellular space to attach adjacent cells together   Desmosome plaque attaches to intermediate filaments that contain protein keratin Prevent epidermal cells from separating under tension and cardiac muscles cells from pulling apart during contraction Gap Junctions  Connect neighboring cells via tiny fluid-filled tunnels called connexons   Contain membrane proteins called connexins Plasma membranes of gap junctions are separated by a very narrow intercellular gap (space)   Communication of cells within a tissue Ions, nutrients, waste, chemical and electrical signals travel through the connexons from one cell to another Epithelial Tissues  Epithelial tissue consists of cells arranged in continuous sheets, in either single or multiple layers     Closely packed and held tightly together Covering and lining of the body Free surface 3 major functions:    Selective barrier that regulates the movement of materials in and out of the body Secretory surfaces that release products onto the free surface Protective surfaces against the environment Connective Tissue   Most abundant and widely distributed tissues in the body Numerous functions      Binds tissues together (tendons/ligaments) Supports and strengthen tissue (bone) Protects and insulates internal organs (fat) Compartmentalize and transport (blood) Energy reserves and immune responses Connective Tissue Extracellular Matrix  Ground substance  Between cells and fibers    Fluid, semifluid, gelatinous, or calcified Functions to support and bind cells, store water, and allow exchange between blood and cells Complex combination of proteins and polysaccharides Fibers    Collagen fibers Elastic fibers Reticular fibers Muscular Tissue  Consists of elongated cells called muscle fibers or myocytes    Cells use ATP to generate force Functions in movement, generating heat, digestion Classified into 3 types: skeletal, cardiac, and smooth muscular tissue Skeletal Muscle Tissue     Attached to bones of the skeleton Have striations Voluntary movement or contractions by conscious control Vary in length (up to 40 cm) and are roughly cylindrical in shape Muscular Tissue  Cardiac muscle tissue    Have striations Involuntary movement or contraction is not consciously controlled Intercalated disc unique to cardiac muscle tissue  Walls of hollow internal structures Smooth Tissue Blood Muscle vessels, airways of lungs, stomach, and intestines    Nonstriated Usually involuntary control Nervous Tissue  Consists of two principle types of cells  Neurons or nerve cells  Neuroglia Cellular Movement   Microtubules cilia & flagella Microfilamentsamoeboid movement & muscle cells Vertebrate skeletal muscle   The action of muscle is to always contract Muscles are attached in antagonistic pairs The basic functional unit of muscle Skeletal muscles: striated & multinucleate I=thin H=thick A=thick + thin A A )Myofilaments  http://highered.mcgrawhill.com/sites/0072495855/student_view0/cha pter10/animation__action_potentials_and_mu scle_contraction.html