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Modeling Transmission Dynamics of Infectious Diseases in Shopping Centers Using Agent-Based Simulation Yuan Zhou, Prospective Faculty Industrial Engineering Department Abstract: Friday, January 29, 2016 – 1:00 p.m. IE 205 As infectious diseases remain a major threat to today’s public health, it is critical to understand the characteristics of their transmission in order to develop effective intervention measures. Prior research has focused on modeling of the transmission processes in households and workplaces, while paying little attention to large public venues. Among those places many people interact, shopping centers present inherent complexity and uncertainty in disease modeling because of the dynamic shopping population and their varying shopping behavior. Given the large amount of shoppers during Christmas shopping season, it is especially important to understand, if during a pandemic, how diseases would spread, thus providing public health officials the guidelines to reducing the risk. To address this significant challenge, this research captures the topology and attributes of shopping centers, and develops an Agent-Based Modeling framework. It adequately considers the complexity of five fundamental model components: spatial relationships, characteristics of shopping center patrons, their shopping behaviors, contact structure, and disease transmission mechanism. An illustrative example demonstrates the Influenza transmission in a super-regional shopping center in Buffalo, New York. Simulation results correspond well to the public surveillance data. Preliminary results of this research indicate that disease transmission processes in a shopping center are driven primarily by local epidemic phases and the shopping behavior. The proposed framework offers the fundamental design modules of an agent-based epidemic model for investigating transmission dynamics of infectious diseases in any shopping centers, and provides a valuable platform for public health agencies to develop intervention strategies. BIOGRAPHY: Dongping Duisisa PhD a PhD candidate in Department the Department of Industrial and Management Systems Yuan Zhou candidate in the of Industrial and Systems Engineering at Engineering the University of South Florida. Her research focuses infectious on nonlinear stochastic University atatBuffalo. Her research focuses on agent-based simulation, disease modeling analysis of complex systems withanalytics applications in healthcare andand systems modeling,and health information technology, and data for healthcare utilization engineering. quality. January 29, 2016 1:00 p.m.