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Review of Rabies cases in the Paediatric Infectious Disease Unit, Mulago Hospital Dr Edison Mworozi Arwanire & Joseph Rujumba Department of Mulago Hospital Email: [email protected] and [email protected] Presented at the Uganda Medical Association & Uganda Veterinary Association 1st International ONE Health Conference 14-16 February 2015 at Hotel Africana, Kampala 1 Overview • • • • • Background Objectives Methods Results Conclusion 2 Background • The Decade of Vaccines Collaboration commits to improving the health and lives of women and children (WHO, UNICEF, NIAID, GAVI Alliance, and Bill & Melinda Gates Foundation 8 October 2012) • Decade of Vaccines Collaboration is a vision to reach all people with the vaccines they need”” (WHO 2013) 3 Background - Rabies • A zoonotic disease caused by the Rabies Virus leading to Rabies encephalitis which is almost always fatal in humans. • Despite being a preventable disease by vaccinating primarily animals and susceptible humans, Rabies affects about 55,000 people globally the majority being in Asia and Africa. 4 Background to Rabies ct’d • It remains a relatively common problem in developing countries including Uganda especially in children. • Is associated with a high case fatality rate. • Mainly due to lack of immunization of domestic animals particularly dogs and humans especially children bitten by such animals due to limited awareness and access to Rabies Vaccine. • Inadequate/lack of PEP 5 Objective To document and highlight the fact that Rabies is a disease of public health importance in children in Uganda. 6 Methods • Conducted a records review of Rabies cases admitted to the pediatric infectious diseases unit of Mulago National Referral Hospital from 1st January 2010- 31st December 2012 documenting – address, – age – sex – duration of hospitalization and – outcome of the cases. 7 Results • From 2010-2012 a total of 13 Children with Rabies were admitted • Majority, 8/13(61.5%) were from Kampala District. • Age range was 1yr and 4 months to 12yrs with an average age of 7.6 yrs . • Almost all of the cases had been bitted by un immunized domestic dogs. 8 Results ct’d • By age category 8/13(61.5%) were aged ≥ 7years, while 4/13(30.8 %) were aged 5-6 years • By gender, 11/13(85%) were males. • All the 13 children (100%) died. • The average duration of stay in hospital was 3.8 days (range 1-13 days) • The majority 7/12(58%) died within 1-3 days of admission. 9 Conclusion • Rabies infection in humans especially children is a public health problem in Uganda with high mortality calling for a concerted effort by veterinary & health professionals to vaccinate all susceptible domestic animals especially dogs and human beings particulary children bitten by such animals. 10 Thank you for your attention 11