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27-1 The Circulatory System Human Biology 11 Ms. Bowie © 2009 The McGraw-Hill Companies, Inc. All rights reserved 27-2 Learning Outcomes Describe the structure of the heart and the function of each part. Trace the flow of blood through the heart. List the most common heart sounds and what events produce them. List the different types of blood vessels and describe the functions of each. Trace the flow of blood through the pulmonary and systemic circulation. List the different types of blood vessels and describe the functions of each. Trace the flow of blood through the pulmonary and systemic circulation. © 2009 The McGraw-Hill Companies, Inc. All rights reserved 27-3 Learning Outcomes (cont.) List and describe the components of blood. Give the functions of red blood cells, the white blood cells, and platelets. List the substances normally found in plasma. Explain how bleeding is controlled. Explain the differences among blood types A, B, AB, and O. Describe the causes, signs and symptoms, and treatments of various diseases and disorders of the cardiovascular system. © 2009 The McGraw-Hill Companies, Inc. All rights reserved 27-4 Part 1 HEART STRUCTURES © 2009 The McGraw-Hill Companies, Inc. All rights reserved 27-5 Introduction The circulatory system consists of heart (a pump) and blood vessels (tubes) Blood is sent to: Lungs for oxygen Digestive system for nutrients Every cell of the body to deliver “products” It also circulates waste products to certain organ systems for removal from the blood © 2009 The McGraw-Hill Companies, Inc. All rights reserved 27-6 The Heart: Structures The heart is an organ about the size of a loose fist Located slightly left of the midline © 2009 The McGraw-Hill Companies, Inc. All rights reserved 27-7 The Heart: Structures (cont.) The Heart has 4 chambers Two atria Upper chambers Left and right Separated by a septum Two ventricles Lower chambers Left and right Separated by a septum © 2009 The McGraw-Hill Companies, Inc. All rights reserved 27-8 The Heart Valves: Structures (cont.) Tricuspid valve – prevents blood from flowing back into the right atrium when the right ventricle contracts Mitral valve – prevents blood from flowing back into the left atrium when the left ventricle contracts Pulmonary valve – prevents blood from flowing back into the right ventricle Aortic valve – prevents blood from flowing back into the left ventricle © 2009 The McGraw-Hill Companies, Inc. All rights reserved 27-10 Part 2 PULMONARY SYSTEM OF CIRCULATION © 2009 The McGraw-Hill Companies, Inc. All rights reserved 27-11 The Heart: Blood Flow Deoxygenated blood in from body Oxygenated blood out to body Oxygenated blood in lungs Deoxygenated blood out to lungs Atria Contract Ventricles Contract © 2009 The McGraw-Hill Companies, Inc. All rights reserved 27-12 The Heart: Blood Flow (cont.) The pulmonary system explains the flow of blood through the heart & lungs. It does not include the rest of the body. © 2009 The McGraw-Hill Companies, Inc. All rights reserved 27-13 Part 3 SYSTEMIC CIRCULATION OF THE BLOOD © 2009 The McGraw-Hill Companies, Inc. All rights reserved 27-14 Blood Vessels: Arteries and Arterioles Carry blood away from the heart Strongest of the blood vessels Under high pressure Arterioles Small branches of arteries Aorta Takes blood from the heart to the body Gives an extra “push” Coronary arteries Supply blood to heart muscle © 2009 The McGraw-Hill Companies, Inc. All rights reserved 27-15 Blood Vessels: Veins and Venules Blood under no pressure in veins Moves blood BACK to the heart Low pressure means that the blood needs help to get back to the heart Muscle contractions in the body help move blood Venules Small vessels formed when capillaries merge Superior and inferior vena cava Largest veins Carry blood into right atrium Valves in the veins prevent backflow © 2009 The McGraw-Hill Companies, Inc. All rights reserved 27-16 Blood Vessels: Capillaries Tiniest branches of arterioles Smallest type of blood vessel Connect arterioles to venules Only about one cell layer thick Oxygen and nutrients can pass out of a capillary into a body cell Carbon dioxide and other waste products pass out of a body cell into a capillary © 2009 The McGraw-Hill Companies, Inc. All rights reserved 27-17 The Heart: Cardiac Cycle The systemic circulation describes the flow of blood through the vessels that supply the body. It does not include the lungs. © 2009 The McGraw-Hill Companies, Inc. All rights reserved 27-18 Part 4 HEART BEAT CARDIAC RHYTHM © 2009 The McGraw-Hill Companies, Inc. All rights reserved 27-19 The Heart: Heart Sounds One cardiac cycle – two heart sounds (lubb and dubb) when valves in the heart snap shut Lubb – First sound When the ventricles contract, the tricuspid and mitral valves snap shut Dubb – Second sound When the atria contract and the pulmonary and aortic valves snap shut © 2009 The McGraw-Hill Companies, Inc. All rights reserved 27-21 Part 5 COMPOSITION OF THE BLOOD © 2009 The McGraw-Hill Companies, Inc. All rights reserved 27-22 Blood Composition © 2009 The McGraw-Hill Companies, Inc. All rights reserved 27-23 Blood A tissue made up of: Red blood cells (erythrocytes) White blood cells (leukocytes) Platelets – cell fragments Plasma – fluid part of blood Average-sized adult has 4 to 6 liters of blood Amount depends on: Size of person Amount of fat tissue Gender - females have less than males © 2009 The McGraw-Hill Companies, Inc. All rights reserved 27-24 Blood Components: Red Blood Cells Erythrocytes Another name for red blood cells Transports oxygen throughout the body Hemoglobin is a pigment in RBCs Oxyhemoglobin carries oxygen; bright red Deoxyhemoglobin does not carry oxygen; darker red Carries carbon dioxide Blood is NEVER actually blue! Anemia Is a condition where a person has a low red blood cell count © 2009 The McGraw-Hill Companies, Inc. All rights reserved 27-25 Blood Components: Platelets Platelets form sticky nets that are important in the blood clotting process. © 2009 The McGraw-Hill Companies, Inc. All rights reserved 27-26 Blood Components: Plasma Liquid portion of blood composed mostly of water Proteins Pull water in to the blood help maintain blood pressure Globulins – transport fats and vitamins Fibrinogen – the “glue” that holds platelets together and are needed for blood clotting Nutrients Albumins Amino acids Glucose Nucleotides Lipids from the digestive tract Gases – oxygen, carbon dioxide, and nitrogen Electrolytes Waste products © 2009 The McGraw-Hill Companies, Inc. All rights reserved 27-27 Part 6 BLOOD TYPES © 2009 The McGraw-Hill Companies, Inc. All rights reserved 27-28 Blood Types Types are distinguished by antigen (“think – gang colours”) and antibodies There are 4 main types: Antigen A (Type A blood) Antigen B (Type B blood) Combination A + B (AB) (Type AB blood) No Antigens at all (called O Type) © 2009 The McGraw-Hill Companies, Inc. All rights reserved 27-29 Blood Types (cont.) Blood Type Antigen Present Antibody Present (Gang colours) (attackers) People with this blood type can receive: A A B Types A and O B B A Types B and O AB AB None ALL Blood Types A and B A, B, AB, and O Only Type O O None © 2009 The McGraw-Hill Companies, Inc. All rights reserved 27-30 Part 7 HEART DISEASE SIGNS & SYMPTOMS © 2009 The McGraw-Hill Companies, Inc. All rights reserved 27-31 Diseases and Disorders of the Cardiovascular System Disease Anemia Description Aneurysm The blood does not have enough red blood cells or hemoglobin to carry an adequate amount of oxygen to the body’s cells A ballooned, weakened arterial wall Arrhythmias Abnormal heart rhythms Carditis Inflammation of the heart Endocarditis Inflammation of the innermost lining of the heart, including valves © 2009 The McGraw-Hill Companies, Inc. All rights reserved 27-32 Diseases and Disorders of the Cardiovascular System (cont.) Disease Description Myocarditis Inflammation of the muscular layer of the heart Pericarditis Inflammation of the membranes that surround the heart (pericardium) Congestive Heart Failure Weakening of the heart over time; heart is unable to pump enough blood to meet body’s needs Coronary Artery Atherosclerosis; narrowing of coronary arteries Disease (CAD) caused by hardening of the fatty plaque deposits within the arteries © 2009 The McGraw-Hill Companies, Inc. All rights reserved 27-33 Diseases and Disorders of the Cardiovascular System (cont.) Disease Description Hypertension High blood pressure; consistent resting blood pressure equal to or greater than 140/90 mm Hg Leukemia Bone marrow produces a large number of abnormal WBCs Murmurs Abnormal heart sounds Myocardial Infarction Heart attack; damage to cardiac muscle due to a lack of blood supply © 2009 The McGraw-Hill Companies, Inc. All rights reserved 27-34 Diseases and Disorders of the Cardiovascular System (cont.) Disease Description Sickle Cell Anemia Abnormal hemoglobin causes RBCs to change to a sickle shape; abnormal cells stick in capillaries Thalassemia Inherited form of anemia; defective hemoglobin chain causes, small, pale, and short-lived RBCs Thrombophlebitis Blood clots and inflammation develops in a vein Varicose Veins Twisted, dilated veins © 2009 The McGraw-Hill Companies, Inc. All rights reserved 27-35 Apply Your Knowledge The doctor has told your patient she has anemia. How would you explain this to the her? ANSWER: Anemia is a condition in which a person does not have enough red blood cells or hemoglobin in the blood to carry an adequate amount of oxygen to body cells. Bravo! © 2009 The McGraw-Hill Companies, Inc. All rights reserved 27-36 In Summary Circulatory system Transport system for body Heart, arteries, veins, and capillaries Blood Transport medium RBCs, WBCs, platelets, plasma © 2009 The McGraw-Hill Companies, Inc. All rights reserved