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Chapter Ten Enhancing Your Cardiovascular Health Health Ch 10 10/27/09 Cardiovascular Disease Cardiovascular • Pertaining to the heart (cardio) and the blood vessels (vasculara) Estimated Prevalence of Major Cardiovascular Diseases Hypertension 72,000,000 Coronary heart disease 15,800,000 Stroke 5,700,000 Congestive heart failure 5,200,000 Congenital heart disease 1,300,000 © 2009 McGraw-Hill Higher Education. All rights reserved. The Vascular System Refers to the blood vessels Arteries carry blood away from the heart • Arterioles are smaller-diameter extensions of arteries Veins carry blood back into the heart • Venules are smaller-diameter extensions of veins Capillaries • Smallest extensions of the vascular system • Site of exchange of oxygen, food, and waste • Blood 45% Red Blood Cells (carry Ox) » 0.7 White Blood Cells 2 % Platelets (assist clotting) » © 2009 McGraw-Hill Higher Education. All rights reserved. Deaths from Cardiovascular Disease © 2009 McGraw-Hill Higher Education. All rights reserved. The Heart Four-chambered pump Size of a fist Function: • Creates pressure to circulate blood throughout the body Location: • Left center of the thorax (between lungs) Signal sends impulses from brain to the heart Electrocardiograph (ECG or EKG) measures the cardiac electrical functioning © 2009 McGraw-Hill Higher Education. All rights reserved. Circulation through the Heart © 2009 McGraw-Hill Higher Education. All rights reserved. Blood Functions of the circulatory system • • • • • • Transportation of nutrients, oxygen, waste products Regulation of water content of cells Regulation of body temperature Buffering of ph level Prevention of blood loss Protection against toxins and microorganisms by circulating antibodies within the bloodstream Average person has 5 quarts of blood © 2009 McGraw-Hill Higher Education. All rights reserved. Risk Factors That Cannot Be Changed Increasing age • Most people who die from heart disease are age 65 and older Male gender • Before age 55, men have a greater risk of heart disease than women do • After menopause, women’s rates of heart disease increase Heredity • Family history • Race/ethnicity negros have higher risk factors for CVD and hypertension © 2009 McGraw-Hill Higher Education. All rights reserved. Risk Factors That Can Be Changed Major Risk Factors: The “Big Six” • Tobacco smoke • Physical inactivity • Abnormal blood cholesterol levels • High blood pressure • Diabetes mellitus • Obesity and overweight Contributing Risk Factor • Individual responses to stress • Type A personality = risk factor © 2009 McGraw-Hill Higher Education. All rights reserved. Risk Factors That Can Be Changed 1. Tobacco smoke Increases risk of heart attack, sudden cardiac death Affects nonsmokers exposed to environmental tobacco smoke Quitting leads to a reduced risk of heart disease 2. Physical inactivity Exercise strengthens the heart muscle, maintains healthy blood vessels Lowers cholesterol levels Encourages weight loss and retention of lean muscle mass Moderates stress © 2009 McGraw-Hill Higher Education. All rights reserved. Risk Factors That Can Be Changed 3. Abnormal Blood Cholesterol Levels Classification of Total Cholesterol, Triglycerides, LDL, and HDL Normal or Desirable BorderlineHigh High Total cholesterol < 200 200-239 ≥ 240 Triglycerides < 150 150-199 ≥ 200 LDL cholesterol < 130 130-159 ≥ 160 Low Normal High (Desirable) < 40 40-59 ≥ 60 HDL cholesterol © 2009 McGraw-Hill Higher Education. All rights reserved. Risk Factors That Can Be Changed 4. High blood pressure Damages heart and blood vessels 5. Diabetes mellitus Increases risk of heart and blood vessel disease Linked to abnormal levels of cholesterol and other blood fats 6. Obesity and overweight Abdominal obesity is especially risky © 2009 McGraw-Hill Higher Education. All rights reserved. Metabolic Syndrome Risk factors often appear in a group Criteria for Metabolic Syndrome • Elevated waist circumference muse 38 in • Men: ≥ 40 inches • Women: ≥ 35 inches • Elevated triglycerides muse 300* • ≥ 150 mg/dL • Reduced HDL cholesterol muse 38 * • Men: < 40 mg/dL • Women: < 50 mg/dL • Elevated blood pressure muse 120 /77 • ≥ 130/85 mmHg • Elevated fasting glucose • ≥ 100 mg/dL © 2009 McGraw-Hill Higher Education. All rights reserved. muse 80 mg/dL Forms of Cardiovascular Disease Coronary heart disease Hypertension Stroke Congenital heart disease Rheumatic heart disease Congestive heart failure Diseases of the arteries Arrhythmias © 2009 McGraw-Hill Higher Education. All rights reserved. Coronary Heart Disease Damage to vessels that supply blood to the heart muscle Atherosclerosis: Buildup of plaque on the inner walls of arteries Myocardial infarction (heart attack): Death of part of the heart muscle Biomarkers • Homocysteine • High sensitivity C-reactive protein If hs-CRP level is lower than 1.0 mg/L, a person has a low risk of developing cardiovascular disease. If hs-CRP is between 1.0 and 3.0 mg/L, a person has an average risk. If hs-CRP is higher than 3.0 mg/L, a person is at high risk. © 2009 McGraw-Hill Higher Education. All rights reserved. Progression of Atherosclerosis © 2009 McGraw-Hill Higher Education. All rights reserved. Cholesterol and Lipoproteins Low-density lipoprotein (LDL) • “Bad” cholesterol High-density lipoprotein (HDL) • “Good” cholesterol To improve cholesterol levels: • Reduce saturated fat intake • Reduce cholesterol intake • Reduce caloric intake to control weight • Take a Statin drug (lipitor, zocor) © 2009 McGraw-Hill Higher Education. All rights reserved. Coronary Heart Disease Angina pectoris: Chest pain with stress or exertion Symptoms of a heart attack include chest pain, shortness of breath, nausea, lightheadedness, back or jaw pain Emergency treatment: CPR and AEDs Diagnosis • • • • • • Blood tests Vital signs Electrocardiogram, echocardiogram Coronary arteriography PET, EBCT, and MRI Nuclear medicine © 2009 McGraw-Hill Higher Education. All rights reserved. Coronary Heart Disease Surgical treatments • Coronary artery bypass surgery • Provides alternative routes for blood to take around points of blockage • Percutaneous coronary intervention • A slender balloon-tipped tube is used to flatten plaque and widen an artery • Heart transplant Nonsurgical treatments • Medications, including aspirin (prevents platelet sticking). © 2009 McGraw-Hill Higher Education. All rights reserved. Statin Drugs Percutaneous Coronary Intervention © 2009 McGraw-Hill Higher Education. All rights reserved. Hypertension Symptoms: “Silent killer” (no symptoms) Screening: Regular checks of resting blood pressure Effects: Heart attacks, strokes, kidney failure, eye damage Classification Blood pressure (mm Hg) Normal Prehypertension Hypertension Systolic (top number) Less than 120 120-139 140 or higher Diastolic (bottom number) Less than 80 80-89 90 or higher © 2009 McGraw-Hill Higher Education. All rights reserved. Hypertension Prevention and treatment • • • • • • • Weight reduction Physical activity Moderation in alcohol use DASH eating plans Salt restriction Stress reduction Medication (lisonopril, B-blockers) © 2009 McGraw-Hill Higher Education. All rights reserved. Stroke Blockage of vessel to the brain Types of stroke • Cerebrovascular occlusions • Cerebral hemorrhage • Cerebral aneurysm Warning sign: Transient ischemic attack (TIA) Diagnosis • Computerized axial tomography (CT) scan • Magnetic resonance imaging (MRI) scan Treatment • Clot dissolving drugs • Cell-rebuilding drugs © 2009 McGraw-Hill Higher Education. All rights reserved. Causes of Stroke © 2009 McGraw-Hill Higher Education. All rights reserved. Congenital Heart Disease Abnormalities present at birth • Caused by environmental factors or illness Types • Valve damage • Holes in the walls of the septum • Blood vessel transportation • Underdevelopment of left side of the heart Treatment • Surgery may be performed to repair malformations © 2009 McGraw-Hill Higher Education. All rights reserved. Rheumatic Heart Disease Chronic damage to the heart (especially the valves) Result of streptococcal infection in the heart • Complication of rheumatic fever Damage tends to occur in valves of the heart Diagnosis: X-rays, echocardiogram Treatment: Surgery © 2009 McGraw-Hill Higher Education. All rights reserved. Congestive Heart Failure Inability of the heart to pump out all the blood that returns to it • Fluid accumulates in veins, lungs, and kidneys Caused by heart damage from other causes Treatment • Rest • Proper diet • Modified daily activities • Use of appropriate drugs © 2009 McGraw-Hill Higher Education. All rights reserved. Diseases of the Arteries Peripheral artery disease (PAD) Blood vessel disease involving changes to the arteries and arterioles in the extremities Causes • Cigarette smoking • Obesity • High-fat diet • Sedentary occupations Treatment • Blood vessel surgery • Medication • Modified lifestyle © 2009 McGraw-Hill Higher Education. All rights reserved. Arrhythmias Irregular beating pattern of the heart caused by disruption of the normal sequence of electrical activity in the heart Can result in loss of consciousness or even death Diagnosis: EKG Treatment: Medication to control heart rate Heart patterns • Bradycardia: Fewer than 60 beats/minute at rest • Tachycardia: More than 100 beats/minute at rest © 2009 McGraw-Hill Higher Education. All rights reserved. CVD Prevention Avoid tobacco Choose a healthy diet Be physically active Control body weight Manage stress Get regular screenings © 2009 McGraw-Hill Higher Education. All rights reserved. © 2009 McGraw-Hill Higher Education. All rights reserved. Chapter Ten: Enhancing Your Cardiovascular Health