Download Key Area 6 Genetic Engineering

Starter Activity:
On a show me board, write down the
explanation of “denatured”.
You could also include examples of when an
enzyme may become denatured.
Key Area 6
Genetic Engineering
Genetic Engineering
Learning Intention: We are learning the process
of genetic engineering.
Success Criteria: Be able to name two hormones
made by genetic engineering.
Be able to describe the genetic engineering
Process.
Be able to state the meaning of a genetically
modified organism.
Insulin
• Diabetics cannot produce insulin.
This means that they cannot
control the level of glucose in their
blood
• They used to inject insulin that
came from cows and pigs.
Problem with that . . .
1. It was a slow and expensive process
2. Some people were allergic to the animal
insulin
3. Some people did not like the idea of
injecting a substance that came from
animals
Genetic Engineering
• Genetic engineering is the transfer of
genetic material from one organism to
another
E.g. Human to bacteria
Genetic Engineering
• This process can be used to get the second
organism to produce a specific protein e.g..
Insulin or Human Growth Hormone
• Bacteria are often used because their
plasmids are easy to remove, alter and
replace.
• A plasmid is a ring of DNA found in bacteria
that is used in genetic engineering.
plasmids
circular
chromosome
gene
bacterium
Plasmid removed
from a
bacterium
Plasmid cut
open
Part of human
chromosome
Gene for insulin
cut out of
chromosome
Gene inserted
into plasmid
Plasmid inserted
into bacterium
Large circular
chromosome
Genetic Engineering
• The bacteria will multiply.
• The hormone can then be extracted and
purified.
• The bacterium is now an organism that
has been genetically modified.
Genetic Engineering
Learning Intention: We are learning the process
of genetic engineering
Success Criteria: Be able to name two hormones
made by genetic engineering
Be able to describe the genetic engineering
process
Be able to state the meaning of a genetically
modified organism
Starter Activity:
Answer the following in sentences in the
back of your notebook:
1) Name two hormones made by genetic
engineering
2) Name the structure removed from
bacteria that the required gene is
inserted into
3) Give a description of the genetic
engineering process
Genetic Engineering
Learning Intention: We are learning the
advantages and disadvantages of genetic
engineering
Success Criteria: Be able to describe the
advantages and disadvantages of genetic
engineering.
Be able to demonstrate the process of genetic
engineering using modelling clay and card.
Advantages of Genetic
Engineering
•
•
•
•
•
Single characteristic can be selected.
Increased range of products.
Very quick.
Increased product purity.
Characteristic can be transferred from
one organism to another.
Disadvantages of Genetic
Engineering
• Risk of release of genetically
engineered bacteria into environment.
• Cost of development is expensive.
• Transfer of antibiotic resistance.
Task
• Using the resources provided by your
teacher, try to describe the process of
genetic engineering to your partner.
Watch and Listen
• Video Clip
Natural Genetic Engineers
• DNA can be transferred naturally
between cells either by bacterial
plasmids or viruses.
Homework
• You must research a genetically
modified organism and present your
findings to the rest of your class in
PowerPoint or Poster format.
• Power Points should be 5-7 slides long
• Posters must be at least A3 size
Genetic Engineering
Learning Intention: We are learning the
advantages and disadvantages of genetic
engineering
Success Criteria: Be able to describe the
advantages and disadvantages of genetic
engineering
Be able to demonstrate the process of genetic
engineering using modelling clay and straws
Lights, Camera, Action!
Your task…
Plan and produce a training video or instruction manual (as a leaflet) for
scientists carrying out genetic engineering of bacteria to make human insulin.
Assessment criteria:
Your clip or leaflet must:
• Be at least 2 minutes/1 side of A4.
• Describe what genetic engineering is.
Your clip or leaflet should:
• Explain the process of genetic engineering using bacteria to make human
insulin.
• Use resources to model the process.
Your clip or leaflet could…
• Describe any safety precautions the scientists must use.
• Describe the advantages of genetic engineering.
• Describe the disadvantages of genetic engineering.
Collect a green slip & glue it into your planner:
Holiday Homework
Preparation for Short Research Report
• You should carry out
research on an area of
biology ,from Key Area 1.6
(your teacher can help
with this).
• You should gather
research on the
background of the
application you are
investigating and impact it
has on the environment
and society.
• This research can be
taken into class and used
to help you write your
report.
• During your first period
back, your teacher will
ask you to write your
report, in class.
• It should be between 50
and 100 words and
include:
1. A description and the
biology involved in the
chosen application being
investigated.
2. The impact it has on the
environment or society.
3. Your references.
Topics for Research Report
• Research current genetic foods/issues
such as golden rice
• less toxic rape seed oil
• bird resistance to bird flu
• tomatoes with longer shelf life
• blight resistant potatoes
• production of medicines for human use
Your first tasks:
1.
Read over your research information and write a brief
summary on a show me board.
2.
In pairs describe the following to each other: the underlying
biology of the application being investigated and impact of the
application on the environment and/or society.
3.
In the back of your notebook write a bullet point plan for your
short research report.
Genetic Engineering: Your topic
Unit 1 Key Area 6: Genetic Engineering.
List the sources you used to find your information.
Once your report has been marked you may be asked some
extra questions.
You will only be asked extra questions if there isn’t enough
information in your report to fully explain the background
information or impact of your application.