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Why do we care? Pathology Hansen’s Disease Bubonic Plague Pathology PLAGUE CURES HOW THEY WORK The smells would help Carry flowers or wear to ward away the a strong perfume disease WHAT THEY REALLY DID Nothing Coat the victims with mercury and place them in oven. Combination of mercury and heat would kill disease. Mercury is poisonous and the oven caused serious burns. Give a strong dose of laxatives Disease is defecated out Strong doses of laxatives can cause death from dehydration. Pathology Pathology Escherichia coli Fermented Foods Medical Research Medications  Vaccines  Restriction enzymes  Environmental Issues  Decomposition  Ethanol  Insecticides  Nitrogen fixation Genetic Recombination  Transformation Bacterium Plasmid with ampicillin resistance absorbs DNA from environment Genetic Recombination  Conjugation  Pilus extends between cells  Copy of a plasmid is donated Plasmid with ampicillin resistance Plasmid with ampicillin resistance Genetic Recombination  Transduction Virus carries host DNA to next host Gene with ampicillin resistance Gene with ampicillin resistance Oxygen Tolerance Obligate Anaerobes Facultative Anaerobes Obligate Aerobes Bacterial Size Bacterial Morphology Bacterial Morphology Coccus Diplococcus Streptococcus Staphylococcus Outer Coverings  Cell Membrane  Wall (peptidoglycan)  Gram+ •Simple, thick wall  Gram •Thin wall •Outer membrane  Capsule  Adheres cell to food  Disguises against host immune system + - A C B E D H F G I Endospores  DNA, ribosomes, and some cytoplasm encased  Bacterial defense against temperature, pH, chemicals, and aridity When Bacteria Attack  Invasion Cells consume host tissues Streptococcus mutans •Cells live on surface of teeth •Exposure to sugar enables production of… •Plaque •Acid When Bacteria Attack Exotoxins  Poisons released to weaken host  Clostridium botulinum  Clostridium tetani  Vibrio cholerae When Bacteria Attack Endotoxins Poisons located in outer membrane Escherichia coli, Salmonella