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Canadian Cancer Statistics 2013 Canadian Cancer Statistics 2013 Canadian Cancer Statistics 2013 Canadian Cancer Statistics 2013 Cancer in Canada MONITORING ORGANS: Cancer Why Use Imaging? • non-invasive way of: – Screening for cancer • ex. mammograms for breast cancer – Diagnosing/staging • ex. location in the body, spread, guiding a biopsy – Guiding cancer treatments • ex. focus on the tumors and minimize damage to surrounding tissue – Determining if a treatment is working – Monitoring for cancer recurrence 1. Ultrasounds • Use of sound above human hearing range to image body structures, including soft tissues • Sounds waves are reflected (echo) off of different density tissues differently 2. X-Rays • Oldest form of imaging • Found by German physicist Wilhelm Rontgen, 1895 • High-energy electromagnetic waves that pass through soft tissue (ex. muscle) but are absorbed by dense tissue (ex. bone) • Can also be used to see soft tissues with the help of stains (ex. bismuth) Most popular use: • Dental x-rays An aside... Electromagnetic radiation - Forms of energy, some on the visible spectrum (light) • Some can be damaging to our DNA, in particular high-energy high-frequency waves (above colour spectrum) 3. CAT Scans: computerized axial tomography scan • An X-ray machine rotates around the patient taking hundreds of individual pictures form many angles • More sensitive than an X-ray alone • Computer re-assembles the picture into a 3-D image, allowing for organs to be viewed section-by-section • Full body scans are still not routinely done due to high incidence of “incidentalomas”, not real issues that show up as issues on the scan • Known to increase chances of cancer in children… 4. MRI (Magnetic Resonance Imaging) • uses radio waves and a strong magnet • different tissues (including tumors) emit a more or less intense signal based on their chemical makeup • produces a three-dimensional images of sections of the body • MRI is sometimes more sensitive than CT scans for distinguishing soft tissues. • can use radioisotopes (unstable atoms) that are injected into the target organ for imaging 5. PET (Positron Emission Tomography) • used to locate a tumor • the patient is given an injection of regular sugar and a small amount of radioactively labeled sugar • because cancer cells take up sugar more than other tissues in the body the tumor is easier to find • large amounts of radiolabelled sugar collect at site of damage “lighting” it up • PET scans are beginning to be used to check if a treatment is working - if tumor cells are dying they use less sugar