Download Molecular Oncology and Immunology Training Program New York University School of Medicine

New York University School of Medicine
Graduate Education in the Department of Pathology
Molecular Oncology and Immunology
Training Program
3D-structure images of nuclei of B-cells to indicate position of antigen receptor genes taken
with confocal microscope.
Training Program in Molecular Oncology and Tumor Immunology
Overview
Training Program in Molecular Oncology and Tumor Immunology
Enormous advances have been made in recent years in understanding the underlying molecular,
cellular, and genetic causes of human cancer. Of particular importance has been the realization of the
interrelationships between oncogenesis, inflammation, and innate and adaptive immunity. The
Molecular Oncology and Tumor Immunology (MOTI) Program offers unique training at the interface
between cancer biology and immunology. The program is divided into two tracks: the Cancer
Biology Track and the Tumor Immunology Track. Coursework provides students with a solid
foundation in all aspects of modern cancer biology, the immune system, and the interrelationship
between the two disciplines, with an emphasis on molecular, genetic, cell biological and
pathophysiological aspects of cancer and immunity, as well as translational discovery and clinical
cancer biology. Research projects in the Program emphasize the study of animal models and human
disease as well as molecular genetic and cell biological approaches. Laboratory research
opportunities run the gamut of basic studies of cancer cell biology, such as cell cycle control, the
function of oncogenes and tumor suppressors, regulation of protein degradation, maintenance of
genome and chromosomal integrity, analysis of the nature and function of cancer stem cells, and
regulation of gene expression and signal transduction pathways; basic studies of tumor progression
over a wide range of cancer models including breast, prostate, bladder, and pancreatic cancer,
melanoma, neuroblastoma and leukemias; and more applied approaches to cancer and immunity,
such as targeted tumor cell killing, tumor gene therapy, production of anti-tumor vaccines, and
immunological and molecular approaches to cancer therapy. The Program brings together
investigators from across the School of Medicine, who employ cutting edge tools of molecular
biology and genetics, sophisticated imaging technologies, and genomewide genetic, chemical, and
proteomic analysis of cancer and immunity.
The program is administered in the Department of Pathology, taking full advantage of being at the
interface of the basic and clinical research efforts of the department, while drawing its faculty from
across many departments and institutes in the School of Medicine.
Director:
David E. Levy, Ph.D.
[email protected]
212-263-8192
Co-Director:
William Carroll, M.D.
[email protected]
212-263-3019
Advisor:
Tony Huang, Ph.D.
[email protected]
212-263-2540
Coordinator:
Cameron Mitchell
[email protected]
212-263-3152
Molecular Oncology/Tumor Immunology Academic Guideline
I. SACKLER REQUIRED COURSES
Course #
Title
BMSC-GA 1997
BMSC-GA 1999
BMSC-GA 2000
BMSC-GA 2001
BMSC-GA 3025
Grant Writing
Scientific Methods: Survival Techniques*
Scientific Integrity and the Responsible Conduct of Research
Foundations of Cell and Molecular Biology I
Individual Development Plan
Semester
Credits
0
0
0
6
1
II. TRAINING PROGRAM-SPECIFIC REQUIRED COURSES
Course #
Title
Prerequisite(s)
BMSC-GA 2002
BMSC-GA 2318
BMSC-GA 4451
Foundations of Cell and Molecular Biology II
Molecular Oncology
Introduction to Biostatistics and Bioinformatics
BMSC-GA 2001
a.
Credits
6
4
3
TUMOR IMMUNOLOGY TRACK
Course #
Title
Prerequisite(s)
BMSC-GA 2306
BMSC-GA 2308
Introduction to Immunology
Advanced Immunology
BMSC-GA 2306
b.
Semester
Semester
Credits
4
4
CANCER BIOLOGY TRACK
Course #
Title
Prerequisite(s)
BMSC-GA 4115
BMSC-GA 4422
Readings in Immunology
Translating Cancer Discovery into Clinical Practice
BMSC-GA 2318
Semester
Credits
2
4
III. RESEARCH/READINGS/SEMINAR/TUTORIAL
Course #
Title
Semester
BMSC-GA 3301/2 Research in Pathology
BMSC-GA 3311/2 Seminar in Pathology (WIP)
BMSC-GA 4112
Reading Course in Molecular Oncology
BMSC-GA 4115
Credits
0.5-12
1.5
1-4
1-4
Readings in Immunology
IV. ELECTIVE COURSES
Course #
Title
BMSC-GA 2210
BMSC-GA 4413
BMSC-GA 4454
BMSC-GA 2106
Molecular Virology
Stem Cell Biology
Molecular Pathology in OMICS Era
Special Topics in Cell Biology: Principles of Protein Modification in
Health and Disease
V. LAB ROTATIONS
Period
October
January
April
PI/Mentor
Prerequisite(s)
Semester
Credits
4
6
4
4
VI. PhD Requirements
a.
b.
c.
Qualifying Exam
! Written Exam
! Oral Exam
! Select PhD Mentoring Committee
Doctoral Thesis
! Approval by committee
! Defend Thesis
Credit Requirements
! 32 credits of graduate coursework
! 40 additional seminar and research credits