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Product datasheet Anti-KCNMB3 antibody [S40B-18] ab94590 1 Image Overview Product name Anti-KCNMB3 antibody [S40B-18] Description Mouse monoclonal [S40B-18] to KCNMB3 Specificity No cross-reactivity against BKBeta1, BKBeta3b or BKBeta4. Tested applications WB, IHC-P, IHC-Fr, ICC/IF Species reactivity Reacts with: Mouse, Rat, Human Immunogen Fusion protein corresponding to amino acids 1-49 (unique N-terminus) of Mouse KCNMB3. Run BLAST with Positive control Run BLAST with Lysate from COS-1 cells transiently transfected with KCNMB3a. Properties Form Liquid Storage instructions Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. Storage buffer Preservative: 0.09% Sodium Azide Constituents: 50% Glycerol, PBS, pH 7.4 Purity Protein G purified Clonality Monoclonal Clone number S40B-18 Isotype IgG1 Applications Our Abpromise guarantee covers the use of ab94590 in the following tested applications. The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user. Application Abreviews Notes WB IHC-P IHC-Fr ICC/IF Application notes ICC/IF: Use at a concentration of 0.1-1.0µg/mL (perox) or 1.0-10µg/mL (IF). 1 IHC-P: Use at a concentration of 0.1-1.0µg/mL (perox) or 1.0-10µg/mL (IF). IHC-Fr: Use at a concentration of 0.1-1.0µg/mL (perox) or 1.0-10µg/mL (IF). WB: Use at a concentration of 1 - 10 µg/ml. Predicted molecular weight: 32 kDa. Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user. Target Relevance MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels composed of the pore-forming alpha subunit and in some tissues a modulatory beta subunit. MaxiK cahannels are fundamental to the control of smooth muscle tone and neuronal excitability. KCNMB3 is a regulatory beta subunit of the MaxiK channel. It modulates the calcium sensitivity and gating kinetics of MaxiK thereby contributing to channel diversity. Cellular localization Membrane. Multi-pass membrane protein. Anti-KCNMB3 antibody [S40B-18] images Predicted band size : 32 kDa Western blot detection of KCNMB3 in Rat brain membrane lysates using ab94590 at 1:1000 dilution. Western blot - Anti-KCNMB3 antibody [S40B-18] (ab94590) Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE" Our Abpromise to you: Quality guaranteed and expert technical support Replacement or refund for products not performing as stated on the datasheet Valid for 12 months from date of delivery Response to your inquiry within 24 hours We provide support in Chinese, English, French, German, Japanese and Spanish Extensive multi-media technical resources to help you We investigate all quality concerns to ensure our products perform to the highest standards If the product does not perform as described on this datasheet, we will offer a refund or replacement. For full details of the Abpromise, please visit http://www.abcam.com/abpromise or contact our technical team. Terms and conditions Guarantee only valid for products bought direct from Abcam or one of our authorized distributors 2