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Ch 2 Performance Objectives • Distinguish between organic and inorganic compounds. • List several salts or their ions important to body functioning. • Describe roles of water and significance of water to homeostasis. • Explain concept of pH and state pH of blood. • List major functions of carbohydrates, lipids, proteins, and nucleic acids. • Define enzyme and explain role of enzymes. • Explain the importance of ATP in the body. Biochemistry: Essentials for Life Organic compounds • carbon • Example: C6H12O6 (glucose) Inorganic compounds • Lack carbon • simpler • Example: H2O (water) Slide 2.21 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Important Inorganic Compounds Water • Most abundant • Vital properties High heat capacity Polarity/solvent Chemical reactivity Cushioning Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Slide 2.22 Important Inorganic Compounds Salts easily dissociates (dissolves) in water Vital to many body functions Include electrolytes -conduct electrical currents Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Slide 2.23 Important Inorganic Compounds • Acids Proton donors release hydrogen ions in water • Bases Proton acceptors Release hydroxide ions in water • Neutralization reaction Acids and bases react to pH 7 (neutral) Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Slide 2.24 pH – power of Hydrogen no. H in substance • Measures relative concentration of H+ pH 7 = neutral pH < 7 = acidic pH > 7 = basic • Buffers Chemicals that can change pH Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Important Organic Compounds • Carbohydrates C,H,O sugars and starches Classified according to size • Monosaccharides – simple sugars • Disaccharides – 2 simple sugars joined • Polysaccharides – long, branching chains of simple sugars Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Slide 2.26 Important Organic Compounds • Lipids • Contain C,H,O • More C & H than O • Mostly C & H • Insoluble in water (hydrophobic) Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Slide 2.29 Important Organic Compounds • Proteins • Made of amino acids • Contain C,O,H,N, sometimes S Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Slide 2.33a Enzymes • biological catalysts • Increase rate of chemical reactions (via decreasing activation energy of Rx) Figure 2.16 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Slide 2.34 Important Organic Compounds Nucleic Acids • blueprint of life • Nucleotide bases • A = Adenine • G = Guanine • C = Cytosine • T = Thymine • U = Uracil Make DNA and RNA Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Slide 2.35 Important Organic Compounds • Adenosine triphosphate (ATP) • Necessary chemical energy used by all cells • Energy released by breaking high energy phosphate bond • ATP is replenished by food fuels • Get most energy from fats (over 120 ATP), then carbs 36-38 ATP), then protein (varies)