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Chapter 3 Carbon Compounds In Cells Producers Capture _______ CO2 + H2O _____ ______ sugars _______ 1. 2. 3. 4. Carbohydrates Lipids Proteins Nucleic acids Global warming- we all agree it is happening •World ____concentrations increase in fall/winter •Overall earth temp. is increasing. •Use of fossil fuels releases ____into atmosphere •Does increased ____ contribute to global warming?? Let’s build life from carbon • Outer shell of carbon has __ electrons • Each carbon atom can form covalent bonds with up to ____ atoms carbon Carbon can be arranged in all sorts of molecules This is ______________ Length or Branched Double bonds Rings ______________ give these molecules their function • There are ___________________ that are most important to the chemistry of life: – 1) __________- OH – 2) ___________-CO – 3) __________-COOH – 4) _________- NH3 – 5) ___________- SH – 6) ___________- PO4 • All are ____________ and___________solubility of organic compounds in water. HYDROXYL CARBOXYL (alcohol) METHYL (non-ionized; —COOH) (ionized; —COO–) (non-ionized; —NH2) (ionized; —+NH3) AMINO CARBONYL PHOSPHATE (aldehyde; —CHO) (ketone; CO) (icon for phosphate group) Fig. 3.2, p. 36 Two major reactions to build and break down macromolecules 1. _____________ Reaction CONDENSATION enzyme action at functional groups • ____ subunits •Water ________ Fig. 3.4a, p. 37 HYDROLYSIS 2. ___________ Reaction • _______ subunits •Water _________ enzyme action at functional groups Fig. 3.4b, p. 37 1. 2. 3. 4. Carbohydrates Lipids Proteins Nucleic acids End in “___” • Monosaccharides- (simple sugars) – _________-tasting – Water soluble – Most have _____ carbons- glucose fructose • Glucose (6 C), Fructose (6 C), Ribose (5 C), Deoxyribose (5 C) glucose fructose •Table sugar is a __________ + H2O sucrose 1. 2. 3. 4. Carbohydrates •___________- (complex Lipids carbohydrates) Proteins •Made by ____________ reaction Nucleic acids • Straight or branched chains of many sugar monomers • Most common are composed entirely of ____________ –______________- tough, indigestible structural material in plants –_________ – easily digestible, used for plant storage –_________- animal storage (in liver and muscles) 1. 2. 3. 4. Carbohydrates • Most include ______________ Lipids – Fats Proteins – Phospholipids Nucleic acids – Waxes • Sterols and their derivatives have no ____________ • Tend to be _____________ in water What is a ___________? • Carbon backbone (up to 36 C atoms) with _________ group (COOH) at one end –______________ - Single bonds between carbons –____________ - One or more double bonds- linked to ______ _______ stearic acid oleic acid linolenic acid What is a ___? • 2 - 3 fatty acid(s) attached to _________ •If one fatty acid is replaced with a ________ group, it become a ______________ • Phospholipids make up cell _________ 1. 2. 3. 4. Carbohydrates Lipids Proteins Nucleic acids Sterols and Derivatives • No fatty acids • Four fused-together carbon ______ • __________- most common type in Waxes animals • Long-chain fatty acids • Firm consistency, repel ______ • Important in _________________ 1. 2. 3. 4. Carbohydrates Lipids Proteins Nucleic acids __________ are the subunit of proteins • Differences in ________ produce the __different valine (val) amino acids. • Amino acids may be: – Non-polar (no ___________ group) – ______ (uncharged, or “+” or “-” charge) Amino acids linked by ______ bonds via ____________________ glutamate (glu) Amino acids linked by _______ bonds via ___________ ________ Condensation reaction Condensation reaction Condensation reaction newly forming polypeptide chain Fig. 3.14, p. 43 1. 2. 3. 4. Carbohydrates Lipids Proteins Nucleic acids •Four levels of structure: ___________._____________, ______________,___________ • Three or more amino acids= ___________ • Backbone of polypeptide has __atoms: -N-C-C-N-C-C-N-C-C-N- • The ______ structure of a protein is its unique _______ of amino acids. • Sickle cell disease, abnormal hemoglobins, is due to a single ________ substitution. Normal Sickle cell D. Proteins D. Proteins • The ________ structure hydrogen bonds at regular intervals along the __________ backbone. – Typical shapes -_______ (an alpha helix) -______(beta pleated sheets). D. Proteins • ______ structure - determined by interactions among between _______ and the _________ backbone. 1. _________ bonds 4. ____________- strong covalent bonds that form between the sulfhydryl groups (SH) of cysteine monomers, stabilize the structure. 2. __________ interactions 3. _____ bonds Fig. 5.22 • _________ structure results from the aggregation of _________ polypeptide subunits. D. Proteins – _________ - fibrous protein of three polypeptides that are supercoiled like a rope. – ____________- a globular protein with ____ copies of ____kinds of polypeptides. Fig. 5.23 Collagen Hemaglobin Protein Denaturation • Disruption of three-dimensional shape • Breakage of weak bonds • Causes of denaturation: – pH – Temperature • Destroying protein shape disrupts function A permanent wave 1. 2. 3. 4. Carbohydrates Lipids Proteins Nucleic acids • A gene consists of regions of DNA, a polymer of _______ _____. • Two types of nucleic acids: _________________ and _______________________ • DNA provides direction for its own replication. • DNA makes ____makes _______. • DNA is the basis of inheritance • One gene synthesizes one ____ 1. 2. 3. 4. Carbohydrates Lipids Proteins Nucleic acids E. Nucleic Acids ______ components in nucleic acids1. _____ • Sugar – Ribose or deoxyribose • Phosphate group • Base – Nitrogen-containing – Single or double ring structure 3. ________ DNA –__ at the “2” carbon RNA –__ at the “2” carbon 2. ____________ Nucleotide Functions • _______ carriers • Coenzymes • Chemical messengers • Building blocks for ________________ ATP - A Nucleotide base three phosphate groups sugar DNA • Double-stranded • Consists of four types of nucleotides – __ bound to __ – __ bound to __ RNA differs from DNA 1. RNA contains ________ as its sugar (not deoxyribose) 2. _________ replaces thymine. AGTCAT becomes AGUCAU 3. An RNA molecule almost always consists of a ________ strand. 4. Three types are key players in protein synthesis This is an H in DNA Natural Toxins • Normal ____________ products of one species that can harm or kill a different species • Natural pesticides – Compounds from _____________ – Compounds from chrysanthemum Synthetic Toxins atrazine DDT malathion Negative Effects of Pesticides • May be toxic to ______________ that help fight pests • May be active for _________________ • Can be accidentally ______________, ______________ by humans • Can cause rashes, headaches, allergic reactions