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Pages 228 - 237 CELLULAR RESPIRATION CELLULAR RESPIRATION Overview of Respiration 1. All organisms respire! 2. Cellular respiration is like the reverse reaction of photosynthesis – Products of photosynthesis become the reactants of cellular respiration – Respiration breaks down glucose (Catabolic Rxn.) 3. ATP energy is released – ATP is used for cellular processes like movement of materials, cellular reproduction, protein synthesis, etc. Glucose CELLULAR RESPIRATION Overview of Respiration 4. What Organelle is involved in cellular respiration? MITOCHONDRIA CELLULAR Overview RESPIRATION of Respiration Two Types of Cellular Respiration: 1. Aerobic (Requires Oxygen) 2. Anaerobic (No oxygen required) Overview of Respiration CELLULAR RESPIRATION (Aerobic) C6H12O6 + 6O2 6CO2 + 6H2O + Energy Ok! Lets look at our Reactants! 1) Glucose 2) Oxygen Wait! You just told me there is a process that does not reqire oxygen?? • This is where it gets confusing…… • For the purposes of this class, we are going to focus on regular cellular respiration which is aerobic (requires oxygen). • However, keep in mind that some simple organisms can only do anaerobic (no oxygen required) cellular respiration. Where do the reactants come from? Glucose - made during Photosynthesis. Oxygen - is in the air. CELLULAR RESPIRATION AEROBIC CellularRESPIRATION Respiration • The formula for aerobic cellular respiration is C6H12O6 + 6O2 → 6CO2 + 6H2O + Energy (ATP) • The “word” equation for this is: CellularRESPIRATION Respiration AEROBIC • Aerobic cellular respiration has 3 stages. 1. Glycolysis 2. Krebs cycle 3. Electron Transport Chain, or ETC Step 1: GLYCOLYSIS Glucose is Broken Down • Inputs: – 1 Glucose – 2 ATP • Outputs: – 2 Pyruvate – 2 NADH – 2 ATP Net (4 ATP made but 2 used = 2 left) Occurs in the CYTOPLASM Step 1: GLYCOLYSIS Per 1 molecule of glucose and 2 molecules of ATP, how many…. Net # of ATP made? NADPH made? Pyruvate made? Where does pyruvate come from? Where does glycolysis take place? Step 2: KREB’S CYCLE AEROBIC RESPIRATION • The step in which pyruvate is broken down • Inputs: – 2 Pyruvate • Outputs: – 2 ATP – 8 NADH – 2 FADH2 – 6 CO2 • Occurs in the mitochondria Step 2: KREB’S CYCLE AEROBIC RESPIRATION Step 3: ELECTRON TRANSPORT CHAIN • In this step, the breakdown of Glucose is completed. • Inputs: – 8 NADH – 2 FADH2 – 6 O2 • Outputs: – 32 ATP – 6 H 2O • Occurs in the mitochondria Step 3: ELECTRON TRANSPORT CHAIN Animation • The mitochondrial electron transport chain is similar to that used in chloroplasts for photosynthesis. NADH and FADH2 molecules formed during Glycolysis and Krebs Cycle carry their electrons to the electron transport chain. The electron transport chain creates a proton gradient that ultimately leads to the production of a large amount of ATP. WOW! MY BRAIN HURTS! Maybe a Video Will Help http://www.youtube.com/watch?v=00jbG_cf GuQ Summary of Aerobic Respiration • Glycolysis breaks down glucose into pyruvate. 2 ATP Made • Pyruvate is further broken down in the Kreb’s Cycle. 2 ATP Made • The electron transport chain finishes breaking down glucose and makes 32 ATP • CO2 and Water are wastes (or byproducts). C6H12O6 + 6O2 6CO2 + 6H2O + ATP 36 ATP MADE TOTAL Cellular Respiration 2 36 Where does Glycolysis take place? Glycolysis What does Glycolysis require? What is step 2 of cellular respiration? Glycolysis Where does the Krebs Cycle take place? Glycolysis What does the Krebs Cycle Make? What does the ETC Use? What does the ETC Make? Cellular respiration when oxygen is NOT present is called ANAEROBIC RESPIRATION ANAEROBIC- NO OXYGEN!! • Some cells can function for a little while without oxygen. • Other Cells may go their entire life without oxygen. But they still need ENERGY!! CELLULAR ANAEROBICRESPIRATION RESPIRATION • Can release energy when oxygen is not present but... • It’s far less efficient. • Begins with glycolysis followed by fermentation. Step 1: GLYCOLYSIS Same as Before: Glucose is Broken Down • Inputs: – Glucose – 2 ATP • Outputs: – 2 Pyruvate – 2 NADH – 4 ATP Occurs in the CYTOPLASM Special Note: Glycolysis can produce thousands of ATP molecules in milliseconds. But quickly fills all available NAD+ (electron carriers) with electrons and the process stops, so it’s only good for short-term energy. ANAEROBIC RESPIRATION Step 2: FERMENTATION 1. Type of anaerobic respiration that releases energy without oxygen 2. If oxygen is not present, the next step is either a. Lactic acid fermentation b. Alcoholic fermentation ANAEROBIC RESPIRATION Step 2: FERMENTATION Lactic Acid Fermentation – Converts pyruvic acid into lactic acid and CO2 – Responsible for food production using microbes (Swiss cheese) – Causes muscle fatigue/burning ANAEROBIC RESPIRATION Step 2: FERMENTATION Alcoholic Fermentation – Converts pyruvic acid into alcohol and CO2 – Responsible for food production using microbes (sourdough bread) Summary Of Fermentation Glycolysis Fermentation 02+ C6H12O6 6CO2 + 6H2O + ATP + alcohol or lactic acid Advantage of Aerobic Respiration Yields 66% more energy 36 net ATP That’s nearly 20 times more ATP than glycolysis alone. Energy Yield without oxygen Glycolysis 4 ATP (gross) Fermentation+ 2 ATP 6 ATP But 2 ATP go back into glycolysis as the energy to start the reaction, so there is only 4 net ATP from anaerobic respiration!!! (32 less than aerobic) Chapter 8 Cellular Energy 8.3 Formative Questions What is the overall purpose of cellular respiration? A. to make ATP B. to process H2O C. to store glucose D. to deliver oxygen Chapter 8 Cellular Energy 8.3 Formative Questions Which represents the general sequence of cellular respiration? A. TCA cycle chemiosmosis B. glycolysis Krebs cycle C. electron absorption phosphorylation D. aerobic pathway fermentation glycolysis electron transport catalysis anaerobic pathway Chapter 8 Cellular Energy 8.3 Formative Questions Which stage of cellular respiration is the anaerobic process? A. glycolysis B. Krebs cycle C. electron transport Chapter 8 Cellular Energy 8.3 Formative Questions Which molecule generated by the Krebs cycle is a waste product? A. CoA B. CO2 C. FADH2 D. NADH Chapter 8 Cellular Energy Standardized Test Practice What prevents pyruvate from entering the Krebs cycle and instead results in this pathway? A. a buildup of CO2 B. a lack of oxygen C. an excess of glucose D. an increased demand for ATP