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RNA Ribonucleic Acid RNA uses the information encoded in DNA to make proteins Structure of RNA RNA is similar to DNA, but there are 3 major differences. RNA is single stranded, DNA is double Ribose is the sugar instead of Deoxyribose Cytosine, Guanine, Adenine and Uracil (instead of Thymine) Types of RNA Three main types 1. Messenger RNA (mRNA) – transfers DNA code to ribosomes for translation. 2. Transfer RNA (tRNA) – brings amino acids to ribosomes for protein synthesis. 3. Ribosomal RNA (rRNA) Ribosomes are made of rRNA and protein. Transcription Transcription is the process of forming RNA from DNA STEPS: 1. Enzyme binds to DNA and separates the DNA strands. 2. The same enzyme then moves along the strand of DNA and assembles the strand of RNA. 3. When the enzyme reaches the termination signal, it releases and the RNA is finished. 4. RNA moves from nucleus to cytoplasm What does the RNA sequence mean??? A codon is a group of 3 letters in the mRNA. The anticodon is the complementary sequence found on the tRNA. Each codon of the mRNA code signal a type of amino acid, a “start code”, or an end to a protein. Use the codon chart to translate the RNA into amino acids Genetic Codes Translation Translation is the process by which the information in RNA is converted into protein. Proteins are long chains of amino acids. Translation Steps 1. 2. 3. 4. mRNA moves to the cytoplasm then to the ribosomes. tRNA “reads” the mRNA until it finds the “start” codon AUG with amino acid methionine. tRNA starts transfering amino acids to ribosome and begins assembly. Ribosomes attach amino acids together forming a protein chain. Protein chain keeps growing until a stop codon is reached. Codons and Amino Acids There are 21 different types of amino acids. AUG is the “start codon” and also signals for the amino acid methionine UAA, UAG, and UGA are “stop codons” and signal the ribosome to release the newly formed protein. Practice DNA: TAC-GAG-CAA-GTC-ACT RNA: AUG-CUC-GUU-CAG-UGA AA: Met Leu Val Glu Stop DNA: TGC-TAC-AGG-TCC-ATT RNA: ACG-AUG-UCC-AGG-UAA AA: Met Ser Arg Stop DNA: TGA-CCG-TAC-GTC-ATC RNA: ACU-GGC-AUG-CAG-UAG AA: Met Glu Stop