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Chapter 9: States of Consciousness Module 22: Drugs https://www.youtube.com/watch?v=9PW1 fwKjo-Y Crash Course 2nd half Psychoactive Drug • A chemical substance that alters perceptions, mood, or behavior • Three common psychoactive drugs: – Caffeine – Alcohol – Nicotine • Induce an altered state of consciousness Dependence • A state of physiological and/or psychological need to take more of a substance after continued use. – Withdrawal follows if the drug is discontinued Withdrawal Tolerance • The discomfort and • Reduced distress that follow responsiveness to a when a person who drug, prompting the is dependent on a user to increase the drug discontinues the dosage to achieve use of the drug effects previously obtained by lower – Withdrawal symptoms are usually doses of the drug the reverse of the drug’s effects. Tolerance Module 22: Drugs Drugs and Neurotransmission Neurotransmission • The process whereby neurons communicate with each other – Neurotransmission, especially in the brain and spinal cord, helps explain the effects of psychoactive drugs. • Psychoactive drugs interfere with normal neurotransmission. Neurotransmitters • Chemical messengers that cross synaptic gaps between neurons – When released by the sending neuron, neurotransmitters travel across the synapse and bind to receptor sites on the receiving neuron, setting up the next link in the chain of communication. Synapse • The junction between the tip of the sending neuron and the receptor sites on the receiving neuron • Call the synaptic gap or cleft Neural Activity Neurotransmitters and the Synapse Reuptake • Process where the unused neurotransmitter chemical is reabsorbed by the sending neuron – How anti-depressants work; they facilitate the reuptake Psychoactive Drugs and Synapses • Psychoactive drugs affect synapses and neurotransmitters in three ways: – Binding with receptors – Blocking receptor site – Blocking neurotransmitters’ reuptake Module 22: Drugs Drug Classifications Five Psychoactive Drug Categories • Five different categories we will study: – #1. Depressants – #2. Opiates – #3. Stimulants – #4. Hallucinogens – #5. Marijuana Module 22: Drugs Drug Classifications: #1. Depressants #1. Depressants • Drugs that reduce neural activity and slow body functioning – Includes alcohol and sedatives Depressants: Alcohol (ethyl alcohol) • Found in beer, wine, and liquor • The second most used psychoactive drug (caffeine first) • Slows thinking, and impairs physical activity • BAC: a measure of how much alcohol is in a person’s bloodstream – BAC of .08 considered legal intoxication in most states Affects of Alcohol Euphoric Memory & Sleep • Alcohol impairs the parts of the brain responsible for controlling inhibitions and making judgments • Studies have shown that alcohol impairs memory by suppressing the processing of events into long term memory. • Alcohol impairs REM sleep, further disrupting memory storage. Do you have an alcohol problem? Depressants: Sedatives • Drugs that reduce anxiety or induce sleep – Also called tranquilizers • Include barbiturates and benzodiazepines Barbiturates • Drugs that depress the activity of the central nervous system and thereby reduce anxiety – Can be lethal in overdose and interact with other drugs, especially alcohol • Impair both memory and judgment • Can create tolerance and dependence Benzodiazepines • Drugs that depress that activity of the central nervous system without most of the side effects associated with barbiturates • Include Valium and Xanax • Can create dependency Module 22: Drugs Drug Classifications: #2. Opiates #2. Opiates • Drugs that depress neural activity, temporarily lesson pain and anxiety • Include: opium, morphine, and heroin Opiates: Morphine • Strong sedative and pain-relieving drug derived from opium • Works by preventing pain neurons from firing or releasing pain-signaling neurotransmitters into the synapse & Endorphins • Natural, opiate-like neurotransmitters linked to pain control and to pleasure • Body’s natural pain killers Module 22: Drugs Drug Classifications: #3. Stimulants #3. Stimulants • Drugs that excite neural activity and speed up body functions • Include: caffeine, nicotine, amphetamines, and cocaine Caffeine • Stimulant found in coffee, chocolate, tea, and some soft drinks • Provides user with a sense of increased energy, mental alertness, and forced wakefulness • Blocks neurological receptor sites that , if activated, sedate the central nervous system Nicotine • Stimulant found in tobacco • Effects similar to those of caffeine • Very addictive and does not stay in the body very long – Explains constant cravings Cocaine • Stimulant derived from leaves of the coca plant – Crack – cocaine crystals • Blocks the reuptake of certain neurotransmitters • Dependency is quick and severe; places extreme strain on cardiovascular system Amphetamines • Drugs that stimulate neural activity, speeding up body functions, with associated energy and mood changes • Includes: speed, uppers, and methamphetamines • Mimic adrenaline • Can cause irreversible changes in mood Cocaine http://www.drugfreeworld.org/reallife-stories/cocaine.html Module 22: Drugs Drug Classifications: #4. Hallucinogens #4. Hallucinogens • Drugs that distort perceptions and evoke sensory images in the absence of sensory input • Include: LSD and ecstasy • Sometimes called “psychedelics” Lysergic Acid Diethylamide (LSD) • Powerful hallucinogenic drug • Also known as “acid” • The effects vary from person to person • Users can be dangerous to themselves and others. Ecstacy • Hallucinogenic drug that produces lower inhibitions, pleasant feelings, and greater acceptance of others • Also called MDMA • Even moderate users may experience permanent brain damage. Module 22: Drugs Drug Classifications: #5: Marijuana #5. Marijuana • Leaves, stems, resin, and flowers form the hemp plant that, when smoked, lower inhibitions and produce feelings of relaxation and mild euphoria • THC (delta-9-tetrahydrocannabinol) is the active ingredient • Disrupts memory; lung damage from smoke In a small group answer: Should marijuana be legalized? • • • • • Why or why not? What would age requirements be? Where could it be bought? For medicinal and/or recreational use? Would it be taxed? • Consider other legal and illegal drugs in your reasoning. Here’s what you said • • • • • • Overwhelmingly yes. 18/21 – discuss other age restrictions Specialty store. Yes – tax: but state or gov’t tax? Medicinal – yes Recreational – only about ½ the groups • A few groups said no – Dangerous, gateway drug, bad habit, etc. Mouse party! • http://learn.genetics.utah.edu/content/addi ction/drugs/mouse.html Module 22: Drugs Prevention: You tell me. High School Drug Use (Johnston & others, 2002)