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Pharmacy Practice II Review I Drugs, old & new “Eye” do No shots for me, thanks Insulin Whatever 200 200 200 200 200 400 400 400 400 400 600 600 600 600 600 800 800 800 800 800 1000 1000 1000 1000 1000 Final Jeopardy Created by Cathy Hamilton old and new for 200 • Two indications for valacyclovir • What are herpes zoster, genital herpes, herpes labialis? old and new for 400 • Indication for tamsulosin • What is BPH? old and new for 600 • Primary adverse effect of erythromycin • What is GI (nausea and vomiting)? old and new for 800 • Specific indication for OTC omeprazole • What is frequent heartburn, 2 or more times a week old and new for 1000 • Active metabolite of amitriptyline? • What is nortriptyline? Eye do for 200 • The first thing a patient should do before administering eye drops • What is wash hands thoroughly? Eye do for 400 • Side effect noted in patients using Xalatan, but not Alphagan • What is change in eye color? Eye do for 600 • Drug class of tobramycin • What is antibiotic (Aminoglycoside)? Eye do for 800 • Type of receptor and action of brimonidine • What is Alpha 2 agonist? Eye do for 1000 • An example of a “disappearing” ophthalmic preservative • What is Purite or Sodium perborate? No shots... for 200 • Of glyburide, Glucophage or Glucotrol, the one least likely to cause hypoglycemia • What is Glucophage (Metformin)? No shots... for 400 • Two metabolic pathways that lead to complications in diabetes • What is advanced glycosylation endproducts and sorbitol pathway? DAILY DOUBLE!! • Two mechanisms of action of Amaryl • What is increased insulin release from pancreas, upregulation of insulin receptors? No shots... for 800 • In addition to monitoring blood glucose levels, patients taking rosiglitazone must also be monitored for this • What is liver function activity (ALT)? No shots... for 1000 • Unpopular adverse effects of alpha glucosidase inhibitors • What are gastrointestinal discomfort, abdominal gas, flatulence, diarrhea? Insulin for 200 • Why insulin cannot be taken orally • What is break down by stomach acid? Insulin for 400 • Most rapid acting insulin • What is Lispro (Humalog and Novalog)? Insulin for 600 • Insulin without a peak • What is glargine (Lantus)? Insulin for 800 • Absence of insulin can cause this life-threatening condition • What is ketoacidosis? Insulin for 1000 • Suspending agents in NPH insulin • What is protamine and zinc? Whatever for 200 • Shaking, sweating, dizzy, hungry, blurred vision, irritability • What are symptoms of hypoglycemia? Whatever for 400 • Polyuria, polydipsia, polyphagia • What are symptoms of diabetes (hyperglycemia)? Whatever for 600 • Volume of fluid in the eye • What is 7-10 microliters? Whatever for 600 • Plasma concentration of glucose that must be exceeded in order for it to be spilled into the urine • What is 180 mg/dL? Whatever for 800 • The leading cause of blindness in people 24-74 y.o. in the industrialized world. • What is diabetic retinopathy? Whatever for 1000 • Cialis may be used to treat this complication of diabetes • What is impotence? Final Jeopardy • Drug originally isolated from the saliva of the Gila monster lizard. • What is Byetta (exenatide)?