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Part One: Etiology & Pathophysiology of Chronic Kidney Disease By T. Parent Nurse Educator, PHC Community Hemodialysis Units 2015 • Identifying the cause of kidney disease enables specific therapy directed at preventing further injury. Where can the damage occur? Environment Micro Macro Diabetes Diabetes is a disease that is caused by the lack of insulin in the body or body’s ability to properly use normal amounts of insulin. Type 1: Juvenile Onset Diabetes • Develops mainly in young people • Is caused by an inability of the pancreas to produce enough insulin • Requires regular insulin injections Type 2: Adult Onset Diabetes • Usually develops in people after their teenage years • The pancreas can produce insulin, but the body has difficulty using it properly • Treatments include diet, exercise and medication (pills, insulin injections or both) How diabetes affects the kidneys Hypertension How old are your Kidneys?