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Mean rates of insulin and glucagon delivery from an artificial pancreas at various blood glucose levels. The device was programmed to establish and maintain normal blood glucose in nine patients with type 1 DM. The values for hormone output approximate the output of the normal human pancreas. The shape of the insulin curve also resembles the insulin response of incubated β cells to graded concentrations of glucose. (Copyright © 1977 American Diabetes Association. Marliss EB et al. Normalization of glycemia in diabetics during meals with insulin and glucagon delivery by the artificial pancreas. Diabetes. 1977;26:663–72. Reprinted, with permission, from the American Diabetes Association.) Source: Disorders of the Endocrine Pancreas, Pathophysiology of Disease: An Introduction to Clinical Medicine, 7e Citation: Hammer GD, McPhee SJ. Pathophysiology of Disease: An Introduction to Clinical Medicine, 7e; 2013 Available at: http://mhmedical.com/ Accessed: July 28, 2017 Copyright © 2017 McGraw-Hill Education. All rights reserved
