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Chapter 16 The Digestive System Functions of the Digestive System 1. take in food 2. break down food 3. absorb digested molecules 4. provide nutrients 5. eliminate wastes Two Divisions of the Digestive System 1. alimentary canal (digestive tract) • digests and absorbs • oral cavity to anus 2. accessory digestive organs Organs of the Digestive System Figure 14.1 Digestive Tract  muscular tube approximately 9 M long  open at both ends  Wall has 4 layers with some variation due to specific function. Layers of Digestive Tract  innermost: mucosa  epithelial cells which line cavity  attached to connective tissue  surrounded by thin muscular layer  protects tissues of canal  carries out secretion and absorption Layers of Digestive Tract  next: submucosa  thick layer of loose connective tissue housing blood vessels, lymph vessels, and nerves  nourishes surrounding layers of tract Layers of Digestive Tract  next: muscular layer  inner: circular smooth muscle  outer: longitudinal smooth muscle  propels food through digestive tract  contains lots of nerves to control movement and secretion Layers of Digestive Tract  outermost: serosa  visceral peritoneum  protects underlying tissue  secretes serous fluid to keep tract from sticking to other tissues of abdominal cavity Layers of Alimentary Canal Organs Figure 14.3 Mouth (Oral Cavity) Anatomy  teeth – 32 total in adults  incisors, premolars, molars, wisdom teeth  tongue – thick, muscular organ  functions in digestion, taste and speech  attaches to posterior part of mouth and by frenulum  covered by mucous membrane  houses taste buds within papillae  salty, sweet, sour, bitter Mouth (Oral Cavity) Anatomy  tonsils  lingual and palatine  palate – roof of oral cavity  hard = bone  soft = muscle and connective tissue  separates oral and nasal cavities  uvula – fleshy projection of the soft palate Salivary Glands  produce saliva – mixture of mucous and serous fluids  keeps mouth moist  contains enzymes that aid in chemical digestion  3 pairs in oral cavity  parotid – located anterior to ears  secrete serous and mucous fluids  submandibular – base of jaw  ducts open below tongue  secrete more serous than mucous fluids  sublingual – smallest, below tongue  duct opens into floor of oral cavity  secretes thick, stringy mucous fluid Saliva  produce 1 liter a day  serous fluid: parotid and submandibular glands  contains amylase, enzyme to break down starches  lysozyme: reduces bacterial growth in mouth  mucous: contains mucin for lubrication  regulated by parasympathetic stimulation (involuntary nervous system)  increase in secretions with sight, smell, thought of food Processes of the Mouth  mechanical digestion  mastication (chewing) of food  mixing of food with saliva by tongue  chemical digestion  salivary amylase breaks down starches  allow for the sense of taste  NO food absorption occurs in mouth. Swallowing tongue, soft palate, pharynx and esophagus  phase 1: voluntary (mouth)  Bolus (food mass) is forced into pharynx by tongue.  phase 2: involuntary (pharynx)  Pharynx connects mouth and esophagus.  Receptors in pharynx sense food which triggers swallowing reflexes.  Epiglottis covers larynx.  phase 3: involuntary (esophagus)  Esophagus connects pharynx to stomach.  Peristalsis moves food from esophagus to stomach.  Lower esophageal sphincter helps prevent regurgitation of food. Stomach Anatomy  located on the left side of the abdominal cavity  Food enters at the cardiac opening. Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Slide Stomach Functions  acts as a storage tank for food  site of food breakdown  start of protein digestion  very little absorption  delivers chyme (processed food) to the small intestine Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Slide Regions of the stomach Cardiac region – near the heart Fundus – most superior part Body Pylorus – funnel-shaped terminal end Food empties into the small intestine at the pyloric sphincter. Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Slide Stomach Anatomy Figure 14.4a Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Slide Muscles of the stomach • different than rest of digestive tract • 3 layers 1. outer longitudinal layer 2. middle circular layer 3. inner oblique layer • produce churning action – mechanical digestion Specialized Mucosa of the Stomach  gastric glands – secrete gastric juice  3 types of cells 1. mucus cells – produce a sticky alkaline mucus which protects stomach lining 2. chief cells – secrete protein-digesting enzymes (pepsinogen which becomes pepsin) 3. parietal cells – secrete hydrochloric acid  rugae – internal folds of the mucosa  allows stomach to stretch when full Other Stomach Secretions • gastrin – hormone that increases stomach secretions • intrinsic factor – aids in absorption of vitamin B12 • cholecystokinin – hormone that stimulates gastric secretions Production of gastric juices is regulated by hormones and the nervous system. Humans produce about 2 L per day. How Stomach Digests Food 1. As food enters digestive tract, gastrin is produced which causes production of gastric juices. 2. Food mixes with gastric juices and forms chyme which passes to pyloric region. 3. As food empties, secretions from stomach wall are inhibited by nervous system. Stomach Movement 2 types resulting from stomach wall muscle contractions 1. mixing – from weak contractions mix ingested food with stomach secretions to form chyme 2. peristalsis – from stronger contractions force chyme toward and through pyloric sphincter Structure of the Stomach Mucosa Figure 14.4b, c Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Slide Small Intestine  absorbs products of digestion  receives secretions from pancreas and liver  transports remaining residue to large intestine  6 meters long  ileocecal junction – joins ileum and large intestine  Ileocecal sphincter and ileocecal valve keep materials moving in right direction. Subdivisions of the Small Intestine Duodenum  attached to the stomach  curves around the head of the pancreas  25 cm long  Common bile duct from liver and pancreatic duct join each other and empty into duodenum. Jejunum  2.5 meters; attaches anteriorly to the duodenum Ileum  3.5 meters, extends from jejunum to large intestine Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Slide Subdivisions of the Small Intestine Duodenum, jejunum and ileum have same structure except:  there is a gradual decrease in diameter  decrease in thickness of the walls  decrease in # of circular folds  decrease in # of villi Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Slide Chemical Digestion in the Small Intestine 3 modifications to increase surface area up to 600 times 1. circular folds – run perpendicular to long axis of tract 2. villi – tiny finger-like projections formed by mucosa 3. microvilli – extensions of villi found in absorptive cells Mucous Lining of Small Intestine composed of simple columnar epithelium 1. absorptive cells have microvilli produce digestive enzymes absorb digested food 2. goblet cells produce protective mucus 3. granular cells protect intestinal epithelium from bacteria 4. endocrine cells produce regulatory hormones Secretions of the Small Intestine • lubricate and protect intestinal wall from acidic chyme and digestive enzymes • keep chyme in liquid form • produced by mucosa, pancreas, liver • peptidases – break proteins into amino acids • disaccharidases – break down complex sugars into monosaccharides Absorption in the Small Intestine major function of small intestine most in duodenum and jejunum  monosaccharides – absorbed through active transport or facilitated diffusion by villi  amino acids – absorbed through active transport by villi and carried away in blood  fatty acids – dissolve into cell membranes of villi and carried away by lymphatic vessels  water – absorbed through osmosis into villi  electrolytes – absorbed by active transport by villi Movement in the Small Intestine • mixing and propulsion – mechanical breakdown • peristaltic contraction – causes chyme to move along tract; occur along entire digestive tract • segmental contraction – short movements to mix contents Large Intestine     larger in diameter, but shorter than the small intestine 1.5 meters extends from ileocecal valve to anus major functions:  absorption of water, electrolytes, vitamins K and B  elimination of indigestible food (feces)  production of mucus for lubrication  No digestion of food occurs here.  Bacteria produce vitamin K and B. Divisions of the Large Intestine  cecum – saclike first part of the large intestine  appendix  accumulation of lymphatic tissue  hangs from the cecum  colon  ascending  transverse  descending  S-shaped sigmoid (in pelvis)  rectum  anus  external body opening  contains 2 sphincters Large Intestine Figure 14.8 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Slide Structures of the Large Intestine  3 bands of longitudinal muscle  arranged in teniae coli  create haustra (pocket like sacs in wall)  large numbers of goblet cells Absorption in the Large Intestine  no digestive enzymes  absorption of water and electrolytes and vitamins K and B Propulsion in the Large Intestine  mass movements  slow, powerful contractions  move contents toward anus  occur two to three times per day  cover more distance than peristaltic contractions  Presence of feces in the rectum causes a defecation reflex.  Internal anal sphincter is relaxed.  Defecation occurs with relaxation of the voluntary (external) anal sphincter. Pancreas  located behind the stomach  produces digestive enzymes that break down all categories of food  trypsin – protein digestion  pancreatic amylase – starch digestion  lipidase – fat digestion  secreted into the duodenum  Alkaline fluid introduced with enzymes neutralizes acidic chyme. Liver  located on the right side of the body under the diaphragm  consists of four lobes  capable of regeneration  connected to the gall bladder via the common hepatic duct     metabolizes carbohydrates, lipids, proteins stores glycogen, vitamins A,D and B12, iron and blood filters blood, removes toxins and damaged blood cells secretes bile Bile  yellowish, green liquid  includes water, bile salts, bile pigments, cholesterol and electrolytes  Bile salts  emulsify fats.  aid in absorption of fatty acids, cholesterol and some vitamins Gall Bladder  sac found beneath liver  stores bile from the liver  releases bile into the duodenum in the presence of fatty food  release controlled by sphincter muscles  Crystallized bile causes gallstones. Processes of the Digestive System Figure 14.11