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Click here for Final Jeopardy 100 100 100 100 100 100 200 200 200 200 200 200 300 300 300 300 300 300 400 400 400 400 400 400 500 500 500 500 500 500 Name the 4 processes of respiration and describe them… BACK TO GAME Pulmonary ventilation - movement of air into/out of the lungs External respiration - movement of O2 from the lungs to the blood and CO2 from the blood to the lungs Internal respiration - movement of O2 from the blood to the cell interior and CO2 from the cell interior to the blood. Cellular respiration - the breakdown of glucose, fatty acids and amino acids that occurs in mitochondria and results in production of ATP. It requires O2 and produces CO2. BACK TO GAME Describe Boyle's Law… Equation What the variables stand for Definition BACK TO GAME - Describe the relationship between pressure differences and air flow - Gas pressure in closed container is inversely proportional to volume of container - PV = K P denotes the pressure of the system. V is the volume of the gas k is a constant value representative of the pressure and volume of the system. - Definition: Boyle’s law states that at constant temperature, the absolute pressure and the volume of a gas are inversely proportional. The law can also be stated in a slightly different manner, that the product of absolute pressure and volume is always constant. BACK TO GAME How many lobes make up each lung? BACK TO GAME Right lung: Three lobes Left lung: Two lobes BACK TO GAME List the main factors influencing hemoglobin saturation (5)… BACK TO GAME - Temperature - H+ - PCO2 - PO2, - concentration of BPG (an organic chemical) - blood pH BACK TO GAME Describe the factors that lead to COPD, as well as the symptoms. BACK TO GAME - Exemplified by chronic bronchitis and obstructive emphysema - Patients have a history of: - Smoking - Dyspnea, where labored breathing occurs and gets progressively worse - Coughing and frequent pulmonary infections - COPD victims develop respiratory failure accompanied by hypoxemia, carbon dioxide retention, and respiratory acidosis BACK TO GAME In humans, B lymphocytes typically gain immunocompetence in the… BACK TO GAME BONE MARROW BACK TO GAME ______________ is a key component of our physical barrier to invasion because it is highly resistant to bacterial enzymes and toxins BACK TO GAME KERATIN BACK TO GAME Primary cellular component of the nonimmune portion of the lymph nodes and spleen… BACK TO GAME RETICULAR CELLS BACK TO GAME List the cells of the Immune response… BACK TO GAME •T-cells •Cytotoxic T cells •Helper T cells •Suppressor T cells •Memory T cells BACK TO GAME Macrophages 1. __________ - macrophages in the lungs. 2. __________ - macrophages in the skin. 3. __________ - macrophages in the liver. 4. __________ - macrophages in the brain. 5. __________ - macrophages in the bone. BACK TO GAME 1. dust cells 2. langerhans’ cells 3. kupffer cells 4. microglia cells 5. osteoclast BACK TO GAME T lymphocytes gain immunocompetence in the… BACK TO GAME THYMUS BACK TO GAME List the two most important antimicrobial proteins… - Interferon - Complement BACK TO GAME The most abundant immunoglobulin type is… BACK TO GAME IgG BACK TO GAME Cellular immunity is primarily the function of… BACK TO GAME T-LYMPHOCYTES BACK TO GAME Which of the following are not phagocytes? a)Dust cells b)Eosinophils c)Microglia d)Mast cells e)Plasma cells BACK TO GAME a) b) c) d) e) Dust cells Eosinophils Microglia Mast cells Plasma cells BACK TO GAME Name two processes of digestion BACK TO GAME Chemical and mechanical BACK TO GAME What is the chief function of the large intestine? BACK TO GAME To reabsorb water to prevent dehydration BACK TO GAME Name 3 functions of the stomach BACK TO GAME • Temporary food storage • Control the rate at which food enters the duodenum • Acid secretion and antibacterial action • Fluidisation of stomach contents • Preliminary digestion with pepsin, lipases etc BACK TO GAME What is gastric emptying? BACK TO GAME The rate of movement of food from the antrum of the stomach, through the Pyloric Sphincter (a true sphincter), and into the duodenum BACK TO GAME Which hormone stimulates the gall bladder to contract and discharge bile? BACK TO GAME Cholecystokinin (CKK) BACK TO GAME What is the uppermost portion of the stomach called? BACK TO GAME Fundus BACK TO GAME An anatomical abnormality in which part of the stomach protrudes through the diaphragm and up into the chest. BACK TO GAME Hiatal hernia BACK TO GAME Name the 3 main sections of the small intestine BACK TO GAME Duodenum, Jejunum, and Ileum BACK TO GAME What is the function of the epiglottis and where is it located? BACK TO GAME A small flap of skin that closes over the pharynx to prevent food from entering the trachea and causing choking BACK TO GAME Name the 4 layers of the GI tract from innermost to outermost. Which layer is responsible for peristalsis and segmental contractions? BACK TO GAME - mucosa - submucosa - muscularis - serosa. - The muscularis is responsible for peristalsis BACK TO GAME Symptoms: watery nasal discharge Sneezing Stuffiness sore throat Fatigue muscle aches Headache Fever (occasionally) If the doctor suspects this disease, he will look out for inflamed nasal lining, clear mucus or a BACK TO GAME red throat The Common cold BACK TO GAME The abnormal growth of intestinal-type cells above the border of the stomach into the esophagus. The damage is caused by stomach acid that leaks back into the esophagus. BACK TO GAME Barretts Esophagus BACK TO GAME An ongoing disorder that causes inflammation of the GI tract. It most commonly affects the lower part of the small intestine. The swelling can cause pain and diarrhea. BACK TO GAME Crohn’s Disease BACK TO GAME A condition in which the liver slowly deteriorates and malfunctions due to chronic injury. Scar tissue replaces healthy liver tissue, partially blocking the flow of blood through the liver. Scarring also impairs the liver’s ability to regenerate damaged cells. BACK TO GAME cirrhosis of the liver BACK TO GAME What does GERD stand for? What is it? BACK TO GAME - Gastro Esophageal Reflux Disease. - Is a persistent condition that occurs when the lower esophageal sphincter opens spontaneously, for varying periods of time, or does not close properly and stomach contents rise up into the esophagus. BACK TO GAME FINAL JEOPARDY!!! FINAL JEOPARDY Trace a generic path of the GI tract BACK TO GAME 1. 2. 3. 4. mouth esophagus stomach small intestine (duodenum, jejunum, ileum) 5. large intestine (colon) 6. rectum 7. anus. BACK TO GAME