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					LIPIDS: THE CONDENSED ENERGY CHAPTER 6 Copyright © 2015, 2010, 2005, 1998 by Saunders, an imprint of Elsevier Inc. Lipids: The Condensed Energy  In 2006, added fats and oils provided more calories/day for the average American than any other food group  NHANES data find that only 17% to 20% of population meets the guidelines of <30% of calories from fat Copyright © 2015, 2010, 2005, 1998 by Saunders, an imprint of Elsevier Inc. 2 Classification of Fats  Simple lipids can be found in foods and in the body  Triglycerides  Fatty acids  Structural lipids are produced by the body  Lipoproteins  Phospholipids From Patton KT, Thibodeau GA: Anatomy & Physiology, ed 8. St. Louis: Mosby, 2013. Copyright © 2015, 2010, 2005, 1998 by Saunders, an imprint of Elsevier Inc. 3 Classification of Fats: Simple Lipids  Simple lipids  Saturated fatty acids (SFAs)  Primarily in animal products (meat and dairy)  Implicated in causing  in total and LDL cholesterol, causing an  risk for CVD Barbara Cousins. In Thibodeau GA, Patton KT (eds): Anatomy & Physiology, ed 6. St. Louis: Mosby, 2007.  Monounsaturated fatty acids (MUFAs)  Primarily in plant foods (olive oil, canola oil, peanuts, pecans, almonds, avocados)   HDL cholesterol, which has a protective effect for CVD Copyright © 2015, 2010, 2005, 1998 by Saunders, an imprint of Elsevier Inc. 4 Classification of Fats: Simple Lipids  Trans fatty acid  Found in meats, dairy, stick margarine, shortening, salty snacks, high-fat baked goods, commercial frying fats  High intakes result in elevated total and LDL cholesterol  FDA requires food labels to declare the amounts of trans fat on nutrition labels Copyright © 2015, 2010, 2005, 1998 by Saunders, an imprint of Elsevier Inc. 5 Classification of Fats: Simple Lipids  Polyunsaturated fatty acids (PUFAs)  Essential fatty acids (EFAs)  Linoleic acid (omega-6 FA)—coldwater marine fish, soybean and canola oils, leafy vegetables   Involved in development and function of retina and cerebral cortex  HDL is protective for CVD  Linolenic acid (omega-3 FA)—vegetable oils like corn, safflower, soybean, sunflower Barbara Cousins. In Patton KT, Thibodeau GA: Anatomy & Physiology, ed 8. St. Louis: Mosby, 2013.   Functions in growth, reproduction, and maintenance of skin integrity May  risk of CVD Copyright © 2015, 2010, 2005, 1998 by Saunders, an imprint of Elsevier Inc. 6 Classification of Fats: Compound Lipids  Phospholipids make up 40% of cell membrane (e.g., enamel and dentin)  Synthesized in the body or obtained from the diet  Lipoproteins transport insoluble fats in the blood     High-density lipoproteins (HDLs) Low-density lipoproteins (LDLs) Very-low-density lipoproteins (VLDLs) Chylomicrons  Cholesterol  Precursor for hormones and structural component From Patton KT, Thibodeau GA: Anatomy & Physiology, ed 8. St. Louis: Mosby, 2013. Copyright © 2015, 2010, 2005, 1998 by Saunders, an imprint of Elsevier Inc. 7 Physiological Roles  Concentrated source of energy  Spares protein  Satiety value  Palatability  Aids absorption of fat-soluble vitamins  Provides EFAs  Adipose tissue serves as an energy reserve  Cushions vital organs  Provides insulation and maintains body temperature Copyright © 2015, 2010, 2005, 1998 by Saunders, an imprint of Elsevier Inc. 8 Dietary Fats and Dental Health  Decreased incidence of caries through the following:  Inhibits streptococcal growth  May reduce dissolution of hydroxyapatite by acids  Fat may act as a protective layer and prevent adherence of retentive CHOs or enhance clearance  May delay gastric emptying, enhancing fluoride absorption From Darby ML, Walsh MM: Dental Hygiene: Theory and Practice, ed 3. St. Louis: Saunders, 2015. Copyright © 2015, 2010, 2005, 1998 by Saunders, an imprint of Elsevier Inc. 9 Dietary Fats and Dental Health  Periodontal disease  Studies using 3000 mg of n-6 PUFA and n-3 PUFA  n-6 PUFA   gingival inflammation (significant at  p <0.016 level)  in levels of prostaglandins, arachidonic acid, and leukotrienes   in pocket depth with n-3 (fish oil) and n-6 (borage oil) Copyright © 2015, 2010, 2005, 1998 by Saunders, an imprint of Elsevier Inc. 10 Dietary Requirements  AMDR for total fat 20% to 35% of energy intake  Keep intake of saturated fat, trans fat, and dietary cholesterol as low as possible while still consuming a nutritionally adequate diet  AI for alpha-linolenic acid = 1.1 to 1.6 g/day  AI for linoleic acid = 12 to 17 g/day Copyright © 2015, 2010, 2005, 1998 by Saunders, an imprint of Elsevier Inc. 11 Sources  Principal sources of fat in US diet  Fats and oils  Red meats, poultry, and fish  Dairy products  Combined these sources account for about 90% of total fat intake Copyright © 2015, 2010, 2005, 1998 by Saunders, an imprint of Elsevier Inc. 12 Overconsumption and Health-Related Problems  Obesity  Excessive fat stores is a common disorder  Blood lipid levels (hyperlipidemia)  Strongest dietary determinant of the blood cholesterol level is dietary saturated fat  Trans fats increase risk of CVD twofold to 10-fold  Cancer  Possible link to high-fat diet, but research continues Copyright © 2015, 2010, 2005, 1998 by Saunders, an imprint of Elsevier Inc. 13 Underconsumption and Health-Related Problems  EFA deficiency  Symptoms include dry, scaly, skin; hair loss; impaired wound healing; visual impairment; and impaired reproductive ability  People at risk  People w/fatty malabsorption syndromes (e.g., cystic fibrosis)  Premature babies  Very low-fat diets (<10% of calories from fat) Copyright © 2015, 2010, 2005, 1998 by Saunders, an imprint of Elsevier Inc. 14 Fat Replacers  Method to reduce fat intake  National survey found 88% of US population consumes low-fat, reduced-fat, or fat-free foods and beverages  Types of fat replacers  Fat “substitutes” or “analogs”  Contain less energy than fat  “Fat mimetics”  Mimic properties of fat  Fat “barriers”  Reduce absorption of fats during frying Copyright © 2015, 2010, 2005, 1998 by Saunders, an imprint of Elsevier Inc. 15 Fat Replacers: Classifications  Carbohydrated~Plant polysaccharides  Protein-based~Simplesse  Fat-based~Olean Copyright © 2015, 2010, 2005, 1998 by Saunders, an imprint of Elsevier Inc. 16 Nutrition Considerations  Wise choices of dietary fats  When selecting and preparing meat, poultry, dry beans, and milk or milk products, choose lean, low-fat, or fat-free  Limit intake of fats and oils high in saturated and/or trans fatty acids; choose products low in these  If solid fat is added in cooking, this counts as part of discretionary calorie allowance  Select fish rich in omega-3 fatty acids, such as salmon, trout, and herring Copyright © 2015, 2010, 2005, 1998 by Saunders, an imprint of Elsevier Inc. 17 HEALTH APPLICATION Hyperlipidemia  Discuss major health risks associated with hyperlipidemia  Consider optimum levels of LDL/HDL/triglycerides and patient actions for achieving them  What dietary recommendations might a health provider make for patient’s reduction of hyperlidipemia? Copyright © 2015, 2010, 2005, 1998 by Saunders, an imprint of Elsevier Inc. 18
 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
                                             
                                             
                                             
                                             
                                             
                                             
                                             
                                             
                                             
                                             
                                            